Article
Multidisciplinary Sciences
Muwei Li, Yurui Gao, Zhaohua Ding, John C. Gore
Summary: Heterogeneity of white matter signals was revealed through power spectral analysis, showing differences in local structural-vascular-functional associations.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Aras Kayvanrad, Stephen R. Arnott, Nathan Churchill, Stefanie Hassel, Aditi Chemparathy, Fan Dong, Mojdeh Zamyadi, Tom Gee, Robert Bartha, Sandra E. Black, Jane M. Lawrence-Dewar, Christopher J. M. Scott, Sean Symons, Andrew D. Davis, Geoffrey B. Hall, Jacqueline Harris, Nancy J. Lobaugh, Glenda MacQueen, Cindy Woo, Stephen Strother
Summary: Quality assurance (QA) is crucial in longitudinal and/or multi-site studies to monitor scanner performance over time and location, detecting and controlling for intrinsic differences and changes in scanner performance. Using phantom scans and QA parameters, variations in image resolution measured by the FWHM were identified as a primary source of variance over time for many sites, as well as between sites and between manufacturers. An unexpected range of instabilities affecting individual slices in a number of scanners were also found, with a preprocessing approach to reduce variance and alleviate anomalies identified.
Article
Multidisciplinary Sciences
Ryan Raut, Abraham Z. Snyder, Anish Mitra, Dov Yellin, Naotaka Fujii, Rafael Malach, Marcus E. Raichle
Summary: The study proposes a parsimonious account of the brain-wide spatiotemporal organization influenced by arousal-related traveling waves, which are reflected in spontaneous fMRI signal fluctuations. These waves can explain many features of spontaneous fMRI signal fluctuations, including topographically organized functional connectivity, and have similar propagation patterns in macaque and human brains.
Article
Neurosciences
Muwei Li, Yurui Gao, Adam W. Anderson, Zhaohua Ding, John C. Gore
Summary: Recent studies have shown that the mathematical model used for analyzing fMRI data in gray matter is not suitable for detecting BOLD signals in white matter. Our findings reveal the non-stationary nature of BOLD signals in white matter, with distinct spectral patterns that can be categorized into five recurring modes.
Article
Neurosciences
Quimby N. Lee, Jingyuan E. Chen, Gregory J. Wheeler, Audrey P. Fan
Summary: This study investigates the dynamic relationship between cardiorespiratory activity and the BOLD signal using wavelet analysis. Differences in coherence between the BOLD signal and physiological dynamics are observed across frequencies and brain networks. The phase analysis reveals unique frequency profiles of coherence between the signals. This research provides insights into autonomic states and improves the interpretation of the BOLD signal.
HUMAN BRAIN MAPPING
(2023)
Article
Clinical Neurology
Tine B. Gehrt, Julian Macoveanu, Christopher J. Bailey, Patrick M. Fisher, Karen Johanne Pallesen, Lisbeth Frostholm
Summary: Severe health anxiety is characterized by persistent preoccupation with one's health, and biases in processing health-related stimuli are consistently associated with symptoms. However, the neural correlates of these behavioral abnormalities are poorly understood.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Tong Yue, Jia Zhao, Anguo Fu
Summary: Positive empathy is associated with specific brain regions' activity and functional connectivity, including the right insula, right subgenual cingulate, and right dorsomedial prefrontal cortex. The activity and connections in these regions are related to positive empathy, emotional experience, and self-referential processing.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Neurosciences
Serafeim Loukas, Lara Lordier, Djalel-Eddine Meskaldji, Manuela Filippa, Joana Sa de Almeida, Dimitri Van de Ville, Petra S. Hueppi
Summary: Research indicates that even during the newborn period, familiar music and unfamiliar music are processed differently by the brain. After music listening, functional connectivity between brain regions in all newborns is modulated. Premature infants exposed to music experience enhanced functional connectivity between brain regions after listening to music.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Nicholas A. Hubbard, Monroe P. Turner, Kevin R. Sitek, Kathryn L. West, Jakub R. Kaczmarzyk, Lyndahl Himes, Binu P. Thomas, Hanzhang Lu, Bart Rypma
Summary: By using calibrated functional magnetic resonance imaging, this study found that low-frequency fluctuations of cerebral metabolic rate of oxygen (CMRO2) during resting state exhibited organizational properties similar to previous functional and anatomical connectivity studies. Furthermore, voxel-wise CMRO2 connectivity showed spatial patterns consistent with four specific resting-state subnetworks.
HUMAN BRAIN MAPPING
(2021)
Article
Neurosciences
Yu Mei Xiao, Fan Gan, Hui Liu, Yu Lin Zhong
Summary: The study found that patients with RVO exhibited abnormal synchronous neural activities in the cerebellum, middle occipital gyrus, and inferior temporal gyrus. These findings offer new insight into the neural mechanisms of vision loss in patients with RVO.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Neurosciences
Zachery D. Morrissey, Liang Zhan, Olusola Ajilore, Alex D. Leow
Summary: Resting-state functional magnetic resonance imaging (rs-fMRI) is widely used in connectomics to study the functional relationships between brain regions, facing challenges in modeling negative correlations. The new method rest2vec uses embedding techniques to transform connectomes into low-dimensional vector spaces, aiding in understanding the functional organization of the brain.
Article
Neurosciences
Liandong Lin, Da Chang, Donghui Song, Yiran Li, Ze Wang
Summary: This study investigates the relationship between brain entropy during resting state and brain activations and deactivations during task performance. The results show that lower brain entropy at rest is associated with stronger activations and deactivations in brain regions engaged by the tasks. Higher workload leads to more extensive negative correlations between resting brain entropy and task activations. These findings suggest that resting brain activity can predict task-related brain activity and may facilitate both task activations and deactivations.
Article
Anatomy & Morphology
Claire Deshayes, Veronique Paban, Marie-Helene Ferrer, Beatrice Alescio-Lautier, Caroline Chambon
Summary: Through studying cognitive function and brain resting functional connectivity, this research explored the definition of creative potential. The analysis showed distinct differences in cognitive function and brain connectivity between groups with high and low creative potential.
BRAIN STRUCTURE & FUNCTION
(2021)
Article
Clinical Neurology
Tingting Ji, Xiaodan Li, Jun Chen, Xuemin Ren, Lin Mei, Yue Qiu, Jie Zhang, Shengcai Wang, Zhifei Xu, Hongbin Li, Zheng Li, Yun Peng, Yue Liu, Xin Ni, Jun Tai, Jiangang Liu
Summary: Children with obstructive sleep apnea (OSA) exhibit abnormal neural activities in specific brain regions and impaired cognitive functions, with the former possibly being the neural mechanism of the latter.
Article
Neurosciences
Fengmei Fan, Xuhong Liao, Tianyuan Lei, Tengda Zhao, Mingrui Xia, Weiwei Men, Yanpei Wang, Mingming Hu, Jie Liu, Shaozheng Qin, Shuping Tan, Jia-Hong Gao, Qi Dong, Sha Tao, Yong He
Summary: A study on the developmental trajectories of the default-mode network (DMN) using longitudinal resting-state fMRI data revealed that connectivity strength and network efficiency increased from childhood to adolescence, particularly in midline structures. The identification of three subclusters within the DMN based on divergent developmental rates of nodal centrality highlights the complex developmental patterns of this network system. These findings have implications for understanding the network mechanisms underlying cognitive development in individuals.
Article
Oncology
F. Bartel, M. van Herk, H. Vrenken, F. Vandaele, S. Sunaert, K. de Jaeger, N. J. Dollekamp, C. Carbaat, E. Lamers, E. M. T. Dieleman, Y. Lievens, D. de Ruysscher, S. B. Schagen, M. B. de Ruiter, J. C. de Munck, J. Belderbos
CLINICAL & TRANSLATIONAL ONCOLOGY
(2019)
Article
Biochemical Research Methods
Zhiqing Zhang, Marie L. Groot, Jan C. de Munck
JOURNAL OF BIOPHOTONICS
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Keith S. Cover, Katya M. Duvivier, Pim de Graaf, Rianne Wittenberg, Ruth Smit, Joost P. A. Kuijer, Mark B. M. Hofman, Ben J. Slotman, Ruud M. Verdaasdonk
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2019)
Article
Multidisciplinary Sciences
Fabian Bartel, Hugo Vrenken, Marcel van Herk, Michiel de Ruiter, Jose Belderbos, Joost Hulshof, Jan C. de Munck
Article
Radiology, Nuclear Medicine & Medical Imaging
Sonia I. Goncalves, Clemence Ligneul, Noam Shemesh
MAGNETIC RESONANCE IN MEDICINE
(2019)
Article
Cell Biology
C. Neves, T. Rodrigues, J. Sereno, C. Simoes, J. Castelhano, J. Goncalves, G. Bento, S. Goncalves, R. Seica, M. R. Domingues, M. Castelo-Branco, P. Matafome
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2019)
Article
Endocrinology & Metabolism
Joao Castelhano, Bruno Ribeiro, Mafalda Sanches, Bruno Graca, Joana Saraiva, Barbara Oliveiros, Christian Neves, Tiago Rodrigues, Jose Sereno, Sonia Goncalves, Maria Joao Ferreira, Raquel Seica, Paulo Matafome, Miguel Castelo-Branco
JOURNAL OF DIABETES AND ITS COMPLICATIONS
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sonia Goncalves, Rui Simoes, Noam Shemesh
Summary: The study utilized iRE-MRS to investigate in-vivo downfield spectra in glioma-bearing mice. Results showed significant qualitative differences in tumor spectra compared to control spectra, with modulation of most peaks and changes in relative peak areas between 6.75 and 8.49 ppm, including attenuation of NAA peaks and differences in peak areas for specific resonances.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Clinical Neurology
K. P. A. Baas, J. Petr, J. P. A. Kuijer, A. J. Nederveen, H. J. M. M. Mutsaerts, K. C. C. van de Ven
Summary: This study found that arterial spin-labeling imaging is reproducible at both field strengths and the reproducibility is not significantly correlated with age. At 3T, higher spatial resolution in 3D acquisitions reduced mixing of GM and WM signal, decreasing bias in CBF measurements. Variations in postlabeling delay caused modest effects on CBF measurements.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2021)
Article
Neuroimaging
M. Visser, D. M. J. Mueller, J. M. van Duijn, M. Smits, N. Verburg, E. J. Hendriks, R. J. A. Nabuurs, J. C. J. Bot, R. S. Eijgelaar, M. Witte, M. B. van Herk, F. Barkhof, P. C. de Witt Hamer, J. C. de Munck
NEUROIMAGE-CLINICAL
(2019)
Article
Neuroimaging
Houshang Amiri, Iman Brouwer, Joost P. A. Kuijer, Jan C. de Munck, Frederik Barkhof, Hugo Vrenken
NEUROIMAGE-CLINICAL
(2019)
Proceedings Paper
Engineering, Biomedical
F. Bartel, H. Vrenken, M. van Herk, M. B. de Ruiter, J. Belderbos, J. Hulshof, J. C. de Munck
Proceedings Paper
Engineering, Biomedical
M. Visser, D. Mueller, N. Verburg, R. Eijgelaar, M. Witte, F. Barkhof, P. de Witt Hamer, J. de Munck
Proceedings Paper
Engineering, Biomedical
Zhiqing Zhang, Marie Louise Groot, Jan C. de Munck
Proceedings Paper
Engineering, Biomedical
J. C. de Munck, J. Hulshof
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.