Article
Neurosciences
Ren Calabro, Yizhou Lyu, Yuan Chang Leong
Summary: People are biased towards perceiving outcomes that align with their motivations. This study found that such motivational biases in perceptual decision-making are associated with amygdala activity, rather than frontoparietal regions commonly associated with biases in perceptual decision-making.
Article
Neurosciences
Julia L. Napoli, Corrie R. Camalier, Anna-Leigh Brown, Jessica Jacobs, Mortimer M. Mishkin, Bruno B. Averbeck
Summary: The study found that in a spatial selective listening task, primary auditory cortex (AC) encoded the cue and target characteristics before the dorsolateral prefrontal cortex (dlPFC) and the basolateral amygdala (BLA), and also encoded the monkey's choice at an earlier stage. The similarity between AC and dlPFC responses was eliminated during passive sensory stimulation, suggesting that the strong sensory encoding in dlPFC is contextually gated. The study suggests that unlike in the visual domain, the BLA does not appear to be robustly involved in selective spatial processing in this auditory task.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Psychology, Clinical
Alicja Timm, Tobias Schmidt-Wilcke, Sandra Blenk, Bettina Studer
Summary: This study found that chronic pain patients had stronger reactions to social inequity compared to healthy individuals, leading to anomalies in social decision making and potentially negative impacts on quality of life.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Neurosciences
Lennart Luettgau, Emanuele Porcu, Claus Tempelmann, Gerhard Jocham
Summary: This study used functional magnetic resonance imaging data to show that during SOC, visual stimuli can reinstate cortical patterns representing previously paired gustatory outcomes, and there is increased functional covariation between the OFC region and the amygdala in terms of neural pattern similarity. The data suggest a mechanism through which motivational value is conferred to stimuli that were never paired with reinforcement.
Article
Neurosciences
Norman H. Lam, Thiago Borduqui, Jaime Hallak, Antonio Roque, Alan Anticevic, John H. Krystal, Xiao-Jing Wang, John D. Murray
Summary: The balance between excitation and inhibition in the brain is crucial for cognitive function. In this study, using a cortical circuit model, the researchers found that both increasing and decreasing the excitation/inhibition ratio can impair perceptual decision-making. These impairments manifest in different ways, but overall lead to decreased psychometric performance.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Kenneth I. Vaden, Susan Teubner-Rhodes, Jayne B. Ahlstrom, Judy R. Dubno, Mark A. Eckert
Summary: Extensive increases in cingulo-opercular frontal activity during speech recognition in noise tasks have been linked to a word recognition benefit on the next trial, but the mechanisms behind this effect have been unclear. This study suggests that pre-stimulus cingulo-opercular activity reflects criterion adjustments that determine how much information to collect for word recognition in subsequent trials. These findings provide insight into the role of cingulo-opercular cortex in optimizing speech recognition performance.
Review
Biology
Kate M. Wassum
Summary: Adaptive reward-related decision making requires accurate consideration of the specific outcome and current desirability of each option. The basolateral amygdala (BLA) and orbitofrontal cortex (OFC) collaborate to encode and use detailed reward memories, supporting prediction and inference in decision making. BLA projections to lateral OFC encode outcome-specific reward memories, while projections to medial OFC regulate the use of these memories for reward pursuit decisions.
Article
Biochemistry & Molecular Biology
Eli J. Cornblath, Arun Mahadevan, Xiaosong He, Kosha Ruparel, David M. Lydon-Staley, Tyler M. Moore, Ruben C. Gur, Elaine H. Zackai, Beverly Emanuel, Donna M. McDonald-McGinn, Daniel H. Wolf, Theodore D. Satterthwaite, David R. Roalf, Raquel E. Gur, Dani S. Bassett
Summary: Individuals with 22q11.2DS show diminished delayed frontal-motor feedback signals and emotional memory signals, while early engagement of motor and visual cortices and insular activation are relatively preserved. Differences in cortical surface area, but not cortical thickness, align with an activation pattern associated with face processing in individuals with 22q11.2DS, indicating intact primary visual processing and insular function, but more affected motor feedback, face processing, and emotional memory processes.
MOLECULAR PSYCHIATRY
(2022)
Article
Neurosciences
Jaime J. Castrellon, Shabnam Hakimi, Jacob M. Parelman, Lun Yin, Jonathan R. Law, Jesse A. G. Skene, David A. Ball, Artemis Malekpour, Donald H. Beskind, Neil Vidmar, John M. Pearson, R. McKell Carter, J. H. Pate Skene
Summary: Efforts to explain complex human decisions have focused on competing theories emphasizing utility and narrative mechanisms. This study recorded brain activation patterns during juror decision-making and found that evidence accumulation correlated with both narrative and utility processes, supporting the integration of these two theories in complex decisions.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Psychology, Multidisciplinary
Daniel Pettersson, Magnus Bergquist, Angelica V. Hagsand
Summary: This study aimed to investigate the inconsistent decision-making of police officers when interviewing alcohol-intoxicated witnesses and the potential influence of scientific research as well as pre-existing social norms. The results showed that the level of witness intoxication affected the probability of interview and perceived witness credibility. The study also indicated that police officers lacked research-based knowledge and their decision-making was influenced by research-based information.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Neurosciences
Nicole C. Ferrara, Sydney Trask, Mallika Padival, Jeremy Amiel Rosenkranz
Summary: Prefrontal cortical maturation and adolescent transitions in social engagement coincide, suggesting its influence on social development. The anterior cingulate cortex (ACC) plays a role in social interaction, including its outputs to the basolateral amygdala (BLA). However, there is limited knowledge about ACC-BLA sensitivity to the social environment and its changes during maturation. This study demonstrates that brief isolation affects the ACC-BLA circuit and subsequent social behavior shifts in both adolescent and adult rats, with optogenetic inhibition of the ACC reducing isolation-driven facilitation of social interaction across ages.
Article
Neurosciences
Debra A. Bercovici, Oren Princz-Lebel, Jackson D. Schumacher, Valerie M. Lo, Stan B. Floresco
Summary: The present study investigates the role of the prelimbic (PL) cortex in decision-making processes by manipulating its activity in different phases of the decision process. The results demonstrate that inhibiting PL activity before choice or after outcome significantly affects decision bias and the influence of recent outcomes on subsequent choices. These findings highlight the multifaceted contributions of the PL cortex in decision implementation and contextual integration of action-outcome feedback.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Nicole C. Ferrara, Sydney Trask, Brittany Avonts, Maxine K. Loh, Mallika Padival, J. Amiel Rosenkranz
Summary: The study demonstrates the crucial role of the basolateral amygdala (BLA) in regulating socially-driven behavior, with age and social drive state affecting its activity differently. High social drive state increases BLA neuronal activity, and young rats exhibit higher sensitivity to social opportunities.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Xinmu Hu, Xiaoqin Mai
Summary: Prosocial individuals are more likely to reject unfair offers with stronger emotional reactions compared to proself individuals. Prosocials show greater neural sensitivity to fairness in early processing stages and exhibit stronger fairness effects on ERP components relative to proselfs. Neural responses to unfair vs fair offers, particularly the MFN, play important roles in behavioral responses to unfairness as modulated by SVO.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2021)
Article
Neurosciences
Ivana Orsolic, Maxime Rio, Thomas D. Mrsic-Flogel, Petr Znamenskiy
Summary: The study found that during the decision-making process, sensory evidence activates specific cortical areas, and recruitment of the motor cortex depends on the interaction of sensory evidence and temporal expectation.
Article
Computer Science, Interdisciplinary Applications
Mark L. C. M. Bruurmijn, Wouter Schellekens, Mathijs A. H. Raemaekers, Nick F. Ramsey
Article
Engineering, Biomedical
Max A. van den Boom, Kai J. Miller, Nick F. Ramsey, Dora Hermes
Summary: The study investigated how the design and surgical placement of electrode grids impact the usability of ECoG measurements, finding that grid configurations with a higher number of densely-packed, large-size electrodes are optimal for capturing the dynamics of hand gesture information. In informative regions of the primary sensorimotor cortex, a grid configuration with 3x3 electrodes, 8 mm inter-electrode distance, and 3 mm electrode size achieved the highest decoding accuracy at around 70% three-class classification accuracy.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Multidisciplinary Sciences
Yair Pinto, Edward H. F. de Haan, Maria-Chiara Villa, Sabrina Siliquini, Gabriele Polonara, Claudia Passamonti, Simona Lattanzi, Nicoletta Foschi, Mara Fabri
Article
Anatomy & Morphology
Alessio Fracasso, Anna Gaglianese, Mariska J. Vansteensel, Erik J. Aarnoutse, Nick F. Ramsey, Serge O. Dumoulin, Natalia Petridou
Summary: This study found that positive blood oxygenation level-dependent (BOLD) responses are correlated with high-frequency band (HFB) responses in electrodes responding to visual stimulation, while negative BOLD responses are associated with an absence of HFB power responses and an unexpected decrease in alpha power responses.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Engineering, Biomedical
L. C. M. Bruurmijn, M. Raemaekers, M. P. Branco, M. J. Vansteensel, N. F. Ramsey
Summary: This study investigates the effects of denervation on the movement representation on the ipsilateral sensorimotor cortex, and the results show that decoding both hands from the same hemisphere is possible even years after denervation. This suggests that implantation of motor-electrodes for BCI control may only need to cover a single hemisphere, making surgery less invasive and providing more options for individuals with lateralized damage to the motor cortex.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Rehabilitation
Mariana P. Branco, Elmar G. M. Pels, Femke Nijboer, Nick F. Ramsey, Mariska J. Vansteensel
Summary: The development of effective Brain-Computer Interfaces (BCIs) relies on collaboration between end-users, caregivers, and researchers. This study compared the opinions of prospective BCI users, caregivers, and BCI researchers regarding BCI applications, mental strategies, and timing of information. The results highlighted the need to align research agendas with the needs of end-users and caregivers to advance the development and implementation of BCIs.
DISABILITY AND REHABILITATION-ASSISTIVE TECHNOLOGY
(2023)
Article
Neurosciences
Mark L. C. M. Bruurmijn, Mathijs Raemaekers, Mariana P. Branco, Nick F. Ramsey, Mariska J. Vansteensel
Summary: There is evidence suggesting the importance of the contralateral sensorimotor areas in movement generation, but the exact role of the ipsilateral sensorimotor cortex in unilateral movement control remains unclear. High-field fMRI data showed hand movement representation in the ipsilateral sensorimotor hand area, supporting the notion of transcallosal integrative processes for optimal coordination of hand movements.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Engineering, Biomedical
Maxime Verwoert, Mariska J. Vansteensel, Zachary Freudenburg, Erik J. Aarnoutse, Frans S. S. Leijten, Nick F. Ramsey, Mariana P. Branco
Summary: The study demonstrates that four hand gestures can be effectively decoded using a single bipolar pair, showing the potential for further development of motor-based BCIs.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Engineering, Biomedical
Mansoureh Fahimi Hnazaee, Maxime Verwoert, Zachary Freudenburg, Sandra M. A. van der Salm, Erik J. Aarnoutse, Sacha Leinders, Marc M. Van Hulle, Nick F. Ramsey, Mariska J. Vansteensel
Summary: This study investigates whether non-invasive scalp electroencephalography (EEG) can predict the performance of brain-computer interfaces (BCIs) based on electrocorticography (ECoG). By analyzing the experimental results of participants with locked-in syndrome (LIS) and healthy participants, it was found that EEG can detect the characteristics observed in ECoG signals. These findings provide new insights for predicting the performance of ECoG-BCIs.
JOURNAL OF NEURAL ENGINEERING
(2022)
Article
Neurosciences
Iris I. A. Groen, Giovanni Piantoni, Stephanie Montenegro, Adeen Flinker, Sasha Devore, Orrin Devinsky, Werner Doyle, Patricia Dugan, Daniel Friedman, Nick F. Ramsey, Natalia Petridou, Jonathan Winawer
Summary: Neural responses to visual stimuli exhibit complex temporal dynamics, which can be captured by a computational model. This study demonstrates the integration of various temporal features, such as subadditive temporal summation, adaptation, and slower dynamics at low contrast, within the same experiment. The model accurately captures the temporal dynamics in different regions of the visual cortex.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Engineering, Biomedical
Julia Berezutskaya, Zachary Freudenburg, Mariska J. Vansteensel, Erik J. Aarnoutse, Nick F. Ramsey, Marcel A. J. van Gerven
Summary: This study optimized and validated a decoding approach for speech reconstruction from sensorimotor cortex recordings, demonstrating the importance of machine learning model optimization for achieving high accuracy reconstruction and the potential of sensorimotor cortex reconstruction for intelligible speech. This has significant implications for the development of next-generation BCI technology.
JOURNAL OF NEURAL ENGINEERING
(2023)
Article
Clinical Neurology
Mariska J. Vansteensel, Mariana P. Branco, Sacha Leinders, Zac F. Freudenburg, Anouck Schippers, Simon H. Geukes, Michael A. Gaytant, Peter H. Gosselaar, Erik J. Aarnoutse, Nick F. Ramsey
Summary: Implantable brain-computer interfaces (BCIs) can be used to restore communication with individuals with locked-in syndrome (LIS). However, further validation and speed improvement are needed for future clinical implementation. This article provides procedures and recommendations for recruitment, inclusion, implantation, and training of participants with LIS, aiming to contribute to the methodological standardization of implantable BCI research.
NEUROREHABILITATION AND NEURAL REPAIR
(2022)
Article
Clinical Neurology
Mariana P. Branco, Elmar G. M. Pels, Ruben H. Sars, Erik J. Aarnoutse, Nick F. Ramsey, Mariska J. Vansteensel, Femke Nijboer
Summary: The research assessed the preferences of potential cBCI users regarding applications, control strategies, and timing of information, finding that there was not much difference in opinions between individuals diagnosed with progressive and sudden onset disorders.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Engineering, Biomedical
M. Vermaas, M. C. Piastra, T. F. Oostendorp, N. F. Ramsey, P. H. E. Tiesinga
JOURNAL OF NEURAL ENGINEERING
(2020)
Article
Engineering, Biomedical
Mariana P. Branco, Simon H. Geukes, Erik J. Aarnoutse, Mariska J. Vansteensel, Zachary Freudenburg, Nick F. Ramsey
JOURNAL OF NEURAL ENGINEERING
(2019)
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.
