Article
Gastroenterology & Hepatology
David O. Prichard, Jeffrey Fetzer
Summary: This study suggests that constipated men and women exhibit different recto-anal pressure patterns, with women being more prone to defecatory disorders and men being more likely to have abnormal balloon expulsion tests. These findings are independent of sex-specific physiological differences.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Medicine, General & Internal
Justin Y. van Oostendorp, Pieter van Hagen, Grietje J. H. van der Mijnsbrugge, Ingrid J. M. Han-Geurts
Summary: Anorectal manometry measurements show significant interrater variability. New techniques like 3D high-resolution anorectal manometry (3D-HRAM) have the potential to improve diagnostic accuracy and understanding of defecation disorders. However, the extent of interrater variability in 3D-HRAM is still unknown.
Article
Pediatrics
Anna Maria Caruso, Denisia Bommarito, Vincenza Girgenti, Glenda Amato, Ugo Calabrese, Adele Figuccia, Fabio Baldanza, Francesco Grasso, Emanuela Giglione, Alessandra Casuccio, Mario Pietro Marcello Milazzo, Maria Rita Di Pace
Summary: This study analyzed anal sphincter activity in patients with anorectal malformation (ARM) using Three-Dimensional High Resolution Anorectal Manometry (3D-HRAM). The results revealed a correlation between manometric parameters and clinical outcomes, highlighting spinal malformations and ARM type as important prognostic risk factors for a bad outcome. Specific sphincteric defects can be explored with manometry, enabling tailored bowel management strategies.
Article
Pediatrics
Jiawei Zhao, Yanan Zhang, Yu Xiong, Jingbin Du, Yongwei Chen, Weihong Guo, Jinshi Huang
Summary: This study evaluated the function of the reconstructed anal canal in postoperative anorectal malformations (ARMs) patients using three dimension (3D) high-definition anorectal manometry. The majority of ARMs patients had acceptable functional outcomes, and 3D manometry can objectively assess the reconstructed anal canal function, helping clinicians explore causes of defecation complications and guide further management.
FRONTIERS IN PEDIATRICS
(2023)
Review
Gastroenterology & Hepatology
Desiree F. Baaleman, Monica Malamisura, Marc A. Benninga, Neetu Bali, Karla H. Vaz, Desale Yacob, Carlo Di Lorenzo, Peter L. Lu
Summary: The study aimed to describe the prevalence and clinical characteristics of patients with internal anal sphincter achalasia without Hirschsprung disease among children undergoing anorectal manometry. Patients with IASA had an earlier onset of symptoms and were more likely to have abnormal contrast enema studies compared to those with functional constipation. Patients with IASA had later onset of symptoms and were diagnosed at an older age compared to patients with Hirschsprung disease.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Matthieu Grasland, Nicolas Turmel, Camille Pouyau, Camille Leroux, Audrey Charlanes, Camille Chesnel, Frederique Le Breton, Samer Sheikh-Ismael, Gerard Amarenco, Claire Hentzen
Summary: The study aimed to test a simple, standardized protocol for measuring external anal sphincter (EAS) fatigue and fatigability to better understand its role in the pathophysiology of fecal incontinence. Results indicated that many patients with anorectal disorders experienced EAS fatigue. The protocol was found to be simple and minimally invasive for assessing EAS fatigue and fatigability.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Pediatrics
Alireza S. Keshtgar, Iman M. Selim
Summary: This study compared the use of water-perfused three dimensional high-resolution anorectal manometry (3D-HRARM) and conventional manometry (CM) in the management of chronic idiopathic constipation (CIC) and faecal incontinence (FI) in children. The results showed no significant differences in resting pressure or rectoanal inhibitory reflex (RAIR) threshold between CM and 3D-HRARM. 3D-HRARM provided a more detailed depiction of anorectal pressure profile and its use is valuable in understanding the underlying pathophysiology and planning further treatment.
JOURNAL OF PEDIATRIC SURGERY
(2023)
Article
Gastroenterology & Hepatology
Marcin Banasiuk, Magdalena Elzbieta Dobrowolska, Barbara Skowronska, Justyna Konys, Aleksandra Banaszkiewicz
Summary: This study demonstrated significantly different pressure values obtained with different types of catheters. Normal ranges for conventional manometry cannot be applied to high-resolution systems, and results obtained by different types of manometry cannot be compared without adjustments.
DIGESTIVE DISEASES
(2022)
Article
Gastroenterology & Hepatology
Charlotte Desprez, Guillaume Gourcerol, Celine Savoye-Collet, Valerie Bridoux, Thomas Duflot, Anne-Marie Leroi
Summary: This study investigated the relationship between anal sphincter function and faecal incontinence (FI) subtypes, finding that the anal sphincter distensibility index (DI) using the EndoFLIP(R) system displayed poor predictive performance in distinguishing among FI subtypes.
COLORECTAL DISEASE
(2022)
Article
Acoustics
Stig Norderval, Torunn K. Pedersen, Rowan J. Collinson
Summary: This study assessed the normal female external anal sphincter (EAS) length using 3D endoanal ultrasound, finding that in the normal anterior female anal canal, the EAS is either absent or appears with less than 50% of the thickness of the lateral and posterior EAS within the first 7.2 mm below the distal border of the puborectal muscle.
JOURNAL OF ULTRASOUND IN MEDICINE
(2021)
Article
Gastroenterology & Hepatology
David O. Prichard, Jeffrey R. Fetzer
Summary: This study found that there are significant differences in results obtained by different operators during high-resolution anorectal manometry (HRM), despite using similar instructions. These differences may have a significant impact on the diagnoses and therapies offered to constipated patients.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Article
Pharmacology & Pharmacy
M. Banasiuk, M. Dziekiewicz, L. Dembinski, D. Piotrowski, A. Kaminski, A. Banaszkiewicz
Summary: 3DHRAM is a useful tool for assessing the function of the anorectum in children after surgery for anorectal disorders. The study found that patients with anal atresia had the lowest pressure values, while those with non-retentive fecal incontinence had significantly lower resting pressures compared to asymptomatic children. Additionally, constipated patients had significantly higher urge thresholds compared to asymptomatic patients.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Jean C. Fox, Aoife M. Feighery, Jeffrey R. Fetzer, David O. Prichard
Summary: Patients with limited English proficiency (LEP) may have different results in anorectal testing compared to English proficiency (EP) patients, likely due to differences in disease prevalence caused by referral bias rather than physiological differences or language barriers.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Pharmacology & Pharmacy
M. Banasiuk, M. Dobrowolska, B. Skowronska, J. Konys, A. Chorazyk, E. Szudejko, A. Banaszkiewicz
Summary: This study evaluated constipated children with 3DHRAM and determined a new pediatric cut-off for DD variables. The analysis showed that the percent anal relaxation during straining significantly differed between patients and controls, leading to a new cut-off value of 31% for this variable.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2021)
Article
Gastroenterology & Hepatology
L. Dekker, D. A. van Reijn-Baggen, I. J. M. Han-Geurts, R. J. F. Felt-Bersma
Summary: This study examined the correlation of anal pressures and the possibility to diagnose pelvic floor dyssynergia between digital rectal examination (DRE) and several anorectal function tests. The results showed a good correlation between DRE and sphincter tone measurement, but poor correlation with other anorectal function tests.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2023)