Review
Psychiatry
Alma Delia Genis-Mendoza, Yazmin Hernandez-Diaz, Thelma Beatriz Gonzalez-Castro, Carlos Alfonso Tovilla-Zarate, Rosa Giannina Castillo-Avila, Maria Lilia Lopez-Narvaez, Miguel angel Ramos-Mendez, Humberto Nicolini
Summary: This study conducted a systematic review and meta-analysis to explore the association between TPH1 gene polymorphisms and the risk of suicide behavior. The results revealed a potential link between the A218C polymorphism of TPH1 gene and increased risk of suicide behavior, particularly in the European population. However, no evidence of an association with suicide behavior was found for the A779C and A6526G polymorphisms.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Immunology
Minghang Pei, Xinshu Liu, Peizeng Yang, Chan Zhao, Fei Gao, Yi Qu, Anyi Liang, Junyan Xiao, Meifen Zhang
Summary: IL33/ST2 gene polymorphisms are associated with the development of BDU, with specific alleles showing significant differences in BD patients with different clinical features, indicating the important role of IL33/ST2 in the pathogenesis of BDU.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Behavioral Sciences
Zhang-Lin Liu, Xin-Qiang Wang, Ming-fan Liu, Bao-juan Ye
Summary: The TPH2 gene polymorphisms are associated with depression, with significant results in Chinese subjects. Further biological experiments are needed to understand the effects of different SNPs on depression.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Multidisciplinary Sciences
Mohammad Al-Forkan, Fahmida Binta Wali, Laila Khaleda, Md Jibran Alam, Rahee Hasan Chowdhury, Amit Datta, Md Zillur Rahman, Nazmul Hosain, Mohammad Fazle Maruf, Muhammad Abdul Quaium Chowdhury, N. K. M. Mirazul Hasan, Injamamul Ismail Shawon, Rubhana Raqib
Summary: The study found that CVD patients from arsenic-affected areas had significantly higher concentrations of iAs in their urine, nail, and cardiac tissue samples, and these were associated with specific genotypes. Adjusted analyses also showed associations between iAs concentrations and certain gene polymorphisms, indicating a potential susceptibility role of these SNPs in cardiac tissue injury among CVD patients exposed to iAs.
SCIENTIFIC REPORTS
(2021)
Article
Public, Environmental & Occupational Health
Katharina Wichert, Reiner Hoppe, Katja Ickstadt, Thomas Behrens, Stefan Winter, Robert Herold, Claudia Terschueren, Wing-Yee Lo, Pascal Guenel, Therese Truong, Manjeet K. Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Michael Lush, Irene L. Andrulis, Hermann Brenner, Jenny Chang-Claude, Angela Cox, Simon S. Cross, Kamila Czene, Mikael Eriksson, Jonine D. Figueroa, Montserrat Garcia-Closas, Mark S. Goldberg, Ute Hamann, Wei He, Bernd Holleczek, John L. Hopper, Anna Jakubowska, Yon-Dschun Ko, Jan Lubinski, Anna Marie Mulligan, Nadia Obi, Valerie Rhenius, Mitul Shah, Xiao-Ou Shu, Jacques Simard, Melissa C. Southey, Wei Zheng, Alison M. Dunning, Paul D. P. Pharoah, Per Hall, Douglas F. Easton, Thomas Bruening, Hiltrud Brauch, Volker Harth, Sylvia Rabstein
Summary: Light-at-night affects the biosynthesis and secretion of melatonin, which may increase the risk of breast cancer. This study used a large-scale molecular epidemiology approach to investigate the associations between polymorphisms in melatonin biosynthesis/signaling genes and breast cancer risk. The results suggest that SNPs in TPH2 and MAPK genes may impact the circadian regulation network and contribute to elevated breast cancer risks.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Multidisciplinary Sciences
Rebecca A. Harrison, Vikram Rao, Shelli R. Kesler
Summary: Genetic polymorphisms in select genes have been associated with vulnerability to cognitive impairment, particularly in patients with breast cancer. Chemotherapy-treated breast cancer patients, especially those who are APOE e4 carriers, may experience slower processing speed. Risk-related alleles may influence functional connectivity in specific brain regions, but their impact on cognitive test performance varies.
SCIENTIFIC REPORTS
(2021)
Article
Pharmacology & Pharmacy
Ha-Young Yoon, Tae-Jin Song, Jeong Yee, Junbeom Park, Hye-Sun Gwak
Summary: The study investigated the effects of APOB and APOE gene polymorphisms on bleeding complications in patients receiving DOACs and established a risk scoring system, which can help clinicians predict bleeding risk.
Article
Multidisciplinary Sciences
Aleksandra Grozic, Keaton Coker, Christopher M. Dussik, Marya S. Sabir, Zhela Sabir, Arianna Bradley, Lin Zhang, Jin Park, Steven Yale, Ichiro Kaneko, Maryam Hockley, Lucinda A. Harris, Tisha N. Lunsford, Todd R. Sandrin, Peter W. Jurutka
Summary: This study aimed to identify potential biomarkers and unique gene expression patterns that define the pathological state of irritable bowel syndrome (IBS). Gene expression profiling of colonic tissue samples from 29 participants, including IBS patients and healthy controls, revealed 858 differentially expressed genes potentially characteristic of IBS. After screening and analysis, seven putative IBS biomarkers, including genes involved in serotonin metabolism, were identified.
Article
Health Care Sciences & Services
Malek Zihlif, Amer Imraish, Baeth Al-Rawashdeh, Aya Qteish, Raihan Husami, Rawand Husami, Farah Tahboub, Yazun Jarrar, Su-Jun Lee
Summary: This study found a statistically significant association between multiple ADAM33 genetic polymorphisms and IgE levels, particularly showing a significant relationship between V4 polymorphism and IgE levels in both adults and children. Such findings add to the growing evidence that the ADAM33 gene has a major impact on IgE levels among asthmatic patients of Jordanian origin.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Genetics & Heredity
Shuyong Yu, Ruisha Tu, Zhaowei Chen, Jian Song, Ping Li, Feixiang Hu, Guihong Yuan, Ronglin Zhang, Yini Li
Summary: The study found an association between PTGER4 and PRKAA1 gene polymorphisms and the susceptibility of gastric cancer, particularly in smokers and patients with adenocarcinoma. This provides a new biological perspective for risk assessment and personalized treatment of gastric cancer.
BMC MEDICAL GENOMICS
(2023)
Article
Clinical Neurology
Weam Fageera, Sarojini M. Sengupta, Marie-Eve Fortier, Natalie Grizenko, Svetlana Babienco, Aurelie Labbe, Ridha Joober
Summary: The study found a significant association of the TPH2 rs17110747 variant in female ADHD probands, with potential involvement in behavioral and cognitive dimensions of ADHD. Furthermore, female probands with the G/G genotype showed greater response to placebo.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Funda Cagirir Dindaroglu, Nesrin Eronat, Asude Durmaz, Dilsah Cogulu, Burak Durmaz, Ozgur Cogulu
Summary: The genetic variation in MMP13 was found to be associated with caries experience, while the polymorphism in MMP20 was not.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Medicine, General & Internal
Shuai Zhao, Linlin Han, Ruihui Zhou, Shiqian Huang, Yafeng Wang, Feng Xu, Shaofang Shu, Leiming Xia, Xiangdong Chen
Summary: Sevoflurane-induced agitation is characterized by increases in the depth of anesthesia index, electromyography, heart rate, and mean arterial pressure, as well as a shift towards high frequencies with spikes in EEG. Genetic polymorphisms in the MTRR gene may be associated with susceptibility to agitation.
FRONTIERS IN MEDICINE
(2021)
Article
Endocrinology & Metabolism
Zaihan Zhu, Yanfen Zhang, Ruocen Bai, Ru Yang, Zhongyan Shan, Chunyan Ma, Jun Yang, Dandan Sun
Summary: This study found that miRNA polymorphisms involved in the insulin signaling pathways and the interaction effects of SNP-SNP, SNP-environmental factors were related to T2DM susceptibility in a Chinese population.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Sana Rafaqat, Jaida Manzoor, Rimsha Akhter, Zain Ishaque, Asifa Kamal, Faiza Saleem, Rasheeda Bashir
Summary: This study found a strong genetic association between PTPN22 gene polymorphisms rs2476601 and rs1310182 and type 1 diabetes in Pakistani children.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Microbiology
Sangeun Jun, Jaewoo Yoon
ARCHIVES OF MICROBIOLOGY
(2017)
Article
Clinical Neurology
Smi Choi-Kwon, Mihye Ko, Sang-Eun Jun, Juhan Kim, Kyung-Hee Cho, Hyun-Wook Nah, Hasup Song, Jong S. Kim
CEREBROVASCULAR DISEASES
(2017)
Article
Cell Biology
Gyeong Im Yu, Sang Eun Jun, Dong Hoon Shin
INFLAMMATION RESEARCH
(2017)
Article
Nursing
Claire J. Han, Ruth Kohen, Sangeun Jun, Monica E. Jarrett, Kevin C. Cain, Robert Burr, Margaret M. Heitkemper
Article
Nursing
Mi-Sun Lee, Chang G. Park, Tonda L. Hughes, Sang-Eun Jun, Kum Whang, Nahyun Kim
JOURNAL OF CLINICAL NURSING
(2018)
Article
Behavioral Sciences
Mihye Ko, Smi Choi-Kwon, Sang-Eun Jun, Ju Han Kim, Kyung-Hee Cho, Hyun-Wook Nah, Hasup Song, Jong S. Kim
BRAIN AND BEHAVIOR
(2018)
Article
Nursing
Sang-Eun Jun, Ruth Kohen, Kevin C. Cain, Monica E. Jarrett, Margaret M. Heitkemper
BIOLOGICAL RESEARCH FOR NURSING
(2014)
Article
Gastroenterology & Hepatology
Margaret D. Eugenio, Sang-Eun Jun, Kevin C. Cain, Monica E. Jarrett, Margaret M. Heitkemper
DIGESTIVE DISEASES AND SCIENCES
(2012)
Article
Dermatology
Mi Hye Lee, Sanguk Im, Seung Hyun Shin, Mi Hee Kwack, Sang-Eun Jun, Moon Kyu Kim, Jung Chul Kim, Young Kwan Sung
EXPERIMENTAL DERMATOLOGY
(2012)
Article
Genetics & Heredity
G. I. Yu, S. -E. Jun, H. -C. Cho, K. O. Park, J. -H. Chung, D. H. Shin, I. S. Chung
INTERNATIONAL JOURNAL OF IMMUNOGENETICS
(2015)
Article
Nursing
Margaret Heitkemper, Monica Jarrett, Jun Sang-Eun
JOURNAL OF KOREAN ACADEMY OF NURSING
(2013)
Article
Gastroenterology & Hepatology
M. M. Heitkemper, K. C. Cain, W. Deechakawan, A. Poppe, S-E. Jun, R. L. Burr, M. E. Jarrett
NEUROGASTROENTEROLOGY AND MOTILITY
(2012)
Article
Nursing
Claire J. Han, Monica E. Jarrett, Kevin C. Cain, Sangeun Jun, Margaret M. Heitkemper
BIOLOGICAL RESEARCH FOR NURSING
(2019)
Article
Nursing
Sung-Hee Seok, Sang-Eun Jun
ASIAN ONCOLOGY NURSING
(2016)