Intracellular Ion Channel CLIC1: Involvement in Microglia-Mediated β-Amyloid Peptide(1-42) Neurotoxicity

Neuroinflammation in ageing and in neurodegenerative disease

(2013) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Regulation of the Membrane Insertion and Conductance Activity of the Metamorphic Chloride Intracellular Channel Protein CLIC1 by Cholesterol

(2013) Stella M. Valenzuela et al.   PLoS One

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

Regulation of oxidative stress in long-lived lipopolysaccharide-activated microglia

(2012) Yoko S Kaneko et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification

(2012) Lele Jiang et al.   JOURNAL OF CELL SCIENCE

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

(2011) M. Hinwood et al.   CEREBRAL CORTEX

Ion Channels on Microglia: Therapeutic Targets for Neuroprotection

(2011) Stephen D. Skaper   CNS & Neurological Disorders-Drug Targets

Possible Role of Glia in Cognitive Impairment in Schizophrenia

(2011) Bernhard J. Mitterauer   CNS Neuroscience & Therapeutics

Amyloid-β-induced reactive oxygen species production and priming are differentially regulated by ion channels in microglia

(2011) Tom Schilling et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inhibition of Amyloid-  (A ) Peptide-Binding Alcohol Dehydrogenase-A  Interaction Reduces A  Accumulation and Improves Mitochondrial Function in a Mouse Model of Alzheimer's Disease

(2011) J. Yao et al.   JOURNAL OF NEUROSCIENCE

IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease

(2011) C Barcia et al.   Cell Death & Disease

Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress

(2010) Stefania Averaimo et al.   FEBS LETTERS

TASTPM Mice Expressing Amyloid Precursor Protein and Presenilin-1 Mutant Transgenes Are Sensitive to γ-Secretase Modulation and Amyloid-β42 Lowering by GSM-10h

(2010) Ishrut Hussain et al.   Neurodegenerative Diseases

Oxidation promotes insertion of the CLIC1 chloride intracellular channel into the membrane

(2009) Sophia C. Goodchild et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ25–35

(2009) Yury G. Kaminsky et al.   EXPERIMENTAL NEUROLOGY

Apoptosis-Associated Tyrosine Kinase and Neuronal Cell Death

(2009) Jane P. Hughes et al.   NEUROCHEMICAL RESEARCH

CLIC1 Function Is Required for  -Amyloid-Induced Generation of Reactive Oxygen Species by Microglia

(2008) R. H. Milton et al.   JOURNAL OF NEUROSCIENCE

Aβ1–42 reduces synapse number and inhibits neurite outgrowth in primary cortical and hippocampal neurons: A quantitative analysis

(2008) Nicholas A. Evans et al.   JOURNAL OF NEUROSCIENCE METHODS

Blockade of chloride intracellular ion channel 1 stimulates Aβ phagocytosis

(2008) Silvia Paradisi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

BIOCHEMISTRY: Metamorphic Proteins

(2008) A. G. Murzin   SCIENCE

Comparison of vertebrate and invertebrate CLIC proteins: The crystal structures ofCaenorhabditis elegans EXC-4 andDrosophila melanogaster DmCLIC

(2007) Dene R. Littler et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS