A Novel Approach for Characterization of Cathepsin D Protease and Its Effect on Tau and β-Amyloid Proteins

Mechanisms of tau-induced neurodegeneration

(2009) Khalid Iqbal et al.   ACTA NEUROPATHOLOGICA

Cathepsin D activity protects against development of type AA amyloid fibrils

(2009) J. C. H. van der Hilst et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Synaptic transmission is impaired prior to plaque formation in amyloid precursor protein–overexpressing mice without altering behaviorally-correlated sharp wave–ripple complexes

(2009) D. Hermann et al.   NEUROSCIENCE

Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects

(2009) A.M. Sheikh et al.   NEUROSCIENCE

Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy

(2008) Xin Zheng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

New Insights into the Roles of Endolysosomal Cathepsins in the Pathogenesis of Alzheimers Disease: Cathepsin Inhibitors as Potential Therapeutics

(2008) Azizul Haque et al.   CNS & Neurological Disorders-Drug Targets

Cathepsin D—Many functions of one aspartic protease

(2008) Petr Benes et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease

(2008) Ying Liu et al.   FEBS LETTERS

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

(2008) Sébastien Conus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microtubule-associated protein tau in development, degeneration and protection of neurons

(2008) Jian-Zhi Wang et al.   PROGRESS IN NEUROBIOLOGY

Cathepsin D expression is decreased in Alzheimer's disease fibroblasts

(2006) Lorena Urbanelli et al.   NEUROBIOLOGY OF AGING