Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized 13C magnetic resonance spectroscopic imaging

A Comparison between Radiolabeled Fluorodeoxyglucose Uptake and Hyperpolarized 13C-Labeled Pyruvate Utilization as Methods for Detecting Tumor Response to Treatment

(2015) Timothy H. Witney et al.   NEOPLASIA

On-target Inhibition of Tumor Fermentative Glycolysis as Visualized by Hyperpolarized Pyruvate

(2015) Pankaj Seth et al.   NEOPLASIA

Imaging Cerebral 2-Ketoisocaproate Metabolism with Hyperpolarized 13C Magnetic Resonance Spectroscopic Imaging

(2012) Sadia A Butt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Metabolite kinetics in C6 rat glioma model using magnetic resonance spectroscopic imaging of hyperpolarized [1-13C]pyruvate

(2012) Jae Mo Park et al.   MAGNETIC RESONANCE IN MEDICINE

Bicarbonate and dichloroacetate: Evaluating pH altering therapies in a mouse model for metastatic breast cancer

(2011) Ian F Robey et al.   BMC CANCER

Real-time detection of central carbon metabolism in livingEscherichia coliand its response to perturbations

(2011) Sebastian Meier et al.   FEBS LETTERS

Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging

(2011) Ilwoo Park et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Metabolic pathway visualization in living yeast by DNP-NMR

(2011) Sebastian Meier et al.   Molecular BioSystems

Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors

(2011) I. Park et al.   NEURO-ONCOLOGY

Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma

(2011) H. S. Venkatesh et al.   NEURO-ONCOLOGY

Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma

(2011) Myriam M. Chaumeil et al.   NEUROIMAGE

In vivo characterization of several rodent glioma models by 1H MRS

(2011) Sabrina Doblas et al.   NMR IN BIOMEDICINE

Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance

(2011) M. E. Merritt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate

(2010) Karlos X. Moreno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative phosphorylation in cancer cells

(2010) Giancarlo Solaini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited

(2010) Alexei Vazquez et al.   BMC Systems Biology

p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism

(2010) Prashanth Ak et al.   FASEB JOURNAL

Anticancer drugs that target metabolism: Is dichloroacetate the new paradigm?

(2010) Ioanna Papandreou et al.   INTERNATIONAL JOURNAL OF CANCER

Cerebral Dynamics and Metabolism of Hyperpolarized [1-13C]pyruvate Using Time-Resolved MR Spectroscopic Imaging

(2010) Ralph E Hurd et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In vivo 13C spectroscopy in the rat brain using hyperpolarized [1-13C]pyruvate and [2-13C]pyruvate

(2010) Małgorzata Marjańska et al.   JOURNAL OF MAGNETIC RESONANCE

In vivo 13C magnetic resonance spectroscopy of a human brain tumor after application of 13C-1-enriched glucose

(2010) Jannie P. Wijnen et al.   MAGNETIC RESONANCE IMAGING

Dynamic and high-resolution metabolic imaging of hyperpolarized [1-13C]-pyruvate in the rat brain using a high-performance gradient insert

(2010) Dirk Mayer et al.   MAGNETIC RESONANCE IN MEDICINE

Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1-13C]pyruvate and 13C magnetic resonance spectroscopic imaging

(2010) Sam E. Day et al.   MAGNETIC RESONANCE IN MEDICINE

In vivo MRSI of hyperpolarized [1-13C]pyruvate metabolism in rat hepatocellular carcinoma

(2010) Moses M. Darpolor et al.   NMR IN BIOMEDICINE

Metabolic Modulation of Glioblastoma with Dichloroacetate

(2010) E. D. Michelakis et al.   Science Translational Medicine

Application of subsecond spiral chemical shift imaging to real-time multislice metabolic imaging of the rat in vivo after injection of hyperpolarized13C1-pyruvate

(2009) Dirk Mayer et al.   MAGNETIC RESONANCE IN MEDICINE

Comparison of 18F-FET and 18F-FDG PET in brain tumors

(2009) Dirk Pauleit et al.   NUCLEAR MEDICINE AND BIOLOGY

Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells

(2009) T. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Warburg Effect: Why and How Do Cancer Cells Activate Glycolysis in the Presence of Oxygen?

(2008) Miguel Lopez-Lazaro   Anti-Cancer Agents in Medicinal Chemistry

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

(2008) E D Michelakis et al.   BRITISH JOURNAL OF CANCER

Hyperpolarized 13C Lactate, Pyruvate, and Alanine: Noninvasive Biomarkers for Prostate Cancer Detection and Grading

(2008) M. J. Albers et al.   CANCER RESEARCH

A 140GHz prepolarizer for dissolution dynamic nuclear polarization

(2008) S. Jannin et al.   JOURNAL OF CHEMICAL PHYSICS

Dynamic Nuclear Polarization of [1-13C]pyruvic acid at 4.6 tesla

(2008) Haukur Jóhannesson et al.   JOURNAL OF MAGNETIC RESONANCE

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

(2008) Ferdia A. Gallagher et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dichloroacetate (DCA) sensitizes both wild‐type and over expressingBcl‐2prostate cancer cells in vitro to radiation

(2008) Wengang Cao et al.   PROSTATE