Article
Engineering, Environmental
Wanlin Guo, Jiayin Zhang, Zhihan Sun, William H. Orem, Calin A. Tatu, Niko S. Radulovic, Dragan Milovanovic, Nikola M. Pavlovic, Wan Chan
Summary: The study found significantly higher concentrations of PAHs and phthalate esters in maize and wheat samples from endemic villages in the Balkans. It warns of the potential risks of prolonged coexposure to these environmental contaminants through dietary intake, which may lead to greater toxicity and accelerated development of Balkan endemic nephropathy (BEN).
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Medicinal
Jiayin Zhang, Chi-Kong Chan, Nikola M. Pavlovic, Wan Chan
Summary: This study investigated the effect of different nutrients, food additives, or health supplements on DNA adduct formation by aristolochic acid I (AA-I). It was found that cells cultured in media enriched with fatty acids, acetic acid, and amino acids produced ALI- dA adducts at significantly higher frequencies. On the other hand, the addition of sodium bicarbonate, GSH, and NAC reduced ALI-dA adduct formation rates. These findings provide insights into the impact of dietary habits on cancer and BEN development.
CHEMICAL RESEARCH IN TOXICOLOGY
(2023)
Article
Chemistry, Medicinal
Jiayin Zhang, Kwan-Kit Jason Chan, Wan Chan
Summary: This study investigates the effects of coexposure to phthalate esters, lignite coal-derived phenol, and polycyclic aromatic hydrocarbons (PAHs) on the metabolism and DNA adduct formation of aristolochic acid I (AAI), aiming to understand the etiological mechanism of Balkan endemic nephropathy (BEN). The results show that the presence of environmental pollutants affects the activation and DNA adduct formation of AAI. Thus, this study contributes to a better understanding of the etiology of BEN and provides insights for risk reduction strategies.
CHEMICAL RESEARCH IN TOXICOLOGY
(2022)
Article
Multidisciplinary Sciences
Yusuke Nakakuki, Takashi Hirose, Hikaru Sotome, Min Gao, Daiki Shimizu, Ruiji Li, Jun-Ya Hasegawa, Hiroshi Miyasaka, Kenji Matsuda
Summary: Helically twisted conductive nanocarbon materials are suitable for optoelectronic and electromagnetic molecular devices on the nanometer scale, showing a large effective conjugation length and ultrafast decay dynamics. The extended π-helicenes achieved a large effective conjugation length through helical fusion, leading to an absorption edge in the near-infrared region.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Xiushang Xu, Amy L. Vonder Haar, Rengo Yoshioka, Qizheng Zhang, Serhii Vasylevskyi, Andrew J. Musser, Akimitsu Narita
Summary: A benzo[rst]pentaphene derivative, BPP-MeOPA, was synthesized and characterized by NMR and single-crystal X-ray analysis. Investigation of its photophysical properties, including transient absorption spectroscopy, revealed improved absorption and emission features from an S-1 state with excitonic and charge-transfer character by introducing MeOPA groups.
CHEMICAL COMMUNICATIONS
(2023)
Review
Environmental Sciences
Meng Qiao, Weixiao Qi, Huijuan Liu, Jiuhui Qu
Summary: Oxygenated polycyclic aromatic hydrocarbons (OPAHs) have higher concentrations and toxicity in water environments, posing significant ecological risks to surface water ecosystems.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Chemistry, Organic
Yushi Ohno, Shogo Ando, Daisuke Furusho, Ryoyu Hifumi, Yuuya Nagata, Ikuyoshi Tomita, Shinsuke Inagi
Summary: Here, a facile and selective synthesis of cationic azatriphenylene derivatives was achieved through electrochemical intramolecular cyclization, where the key step involves atom-economical C-H pyridination without a transition-metal catalyst or an oxidant. This proposed strategy provides a practical approach for introducing cationic nitrogen (N (+)) into pi-electron systems, thus expanding the molecular design of N (+)-doped polycyclic aromatic hydrocarbons.
Article
Chemistry, Inorganic & Nuclear
Huimin Zhong, Cong Jiang, Jiahui Zou, Guancheng Zhu, Yanyan Huang
Summary: In this study, CeO2-based porous carbonaceous frameworks (CeO2 PCFs) were used as antioxidant nanozymes to scavenge reactive oxygen species and absorb benzo[a]pyrene. CeO2 PCFs exhibited excellent superoxide dismutase-like and catalase-like activity, effectively eliminating superoxide radical, hydroxyl radical, and hydrogen peroxide. The 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) free radical scavenging assay confirmed the free radical scavenging ability of CeO2 PCFs. Furthermore, CeO2 PCFs with large surface area and porous structure efficiently adsorbed benzo[a]pyrene. The designed CeO2 PCFs can serve as new antioxidant nanozymes for scavenging reactive oxygen species and adsorbing polycyclic aromatic hydrocarbons (PAHs).
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Thomas Liu, Baptiste Carles, Christine Elias, Claire Tonnele, Daniel Medina-Lopez, Akimitsu Narita, Yannick Chassagneux, Christophe Voisin, David Beljonne, Stephane Campidelli, Loic Rondin, Jean-Sebastien Lauret
Summary: In this study, we conducted single-molecule spectroscopy at cryogenic temperatures to investigate the optical properties of graphene quantum dots (GQDs). We found that temperature has an effect on the spectral characteristics of GQDs, and we used density functional theory calculations to explain these observations. Additionally, we discovered that the vibrational features can serve as a unique fingerprint for identifying GQDs.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Review
Environmental Sciences
Jamie M. Dearnley, Charles Killeen, Rebecca L. Davis, Vince P. Palace, Gregg T. Tomy
Summary: This article reviews the metabolism and toxicity of polycyclic aromatic compounds (PACs) in fish and presents various methods for analyzing metabolite-containing bile. Recent environmental monitoring studies demonstrate the utility of this technique in assessing oil spill pollution, establishing baseline exposure, and evaluating pollution in urban waterways.
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Environmental
Jiaxing Lu, Jian Zhang, Huijun Xie, Yuming Jing, Mingde Ji, Zhen Hu
Summary: In this study, a novel wastewater treatment process combining sequencing batch reactor, constructed wetland and microalgal membrane photobioreactor (BCM process) was proposed. The process achieved satisfactory removal of polycyclic aromatic hydrocarbons (PAHs) and their substituted derivatives (SPAHs), and significantly reduced bacterial toxicity and genotoxicity. Microalgae played an important role in ensuring water security.
Article
Engineering, Environmental
Zhiyang Lu, Weijun Tian, Surong Zhang, Meile Chu, Jing Zhao, Bingkun Liu, Kun Yang, Huimin Cao, Zhuo Chen
Summary: This study investigated the spatiotemporal distribution, source, and ecological risk of PAHs and SPAHs in surface sediments in Laizhou Bay. The results showed seasonal differences in concentrations of PAHs and SPAHs and a spatial distribution trend of estuary > coast > offshore. Combustion sources, including petroleum, coal, and biomass, were identified as the main contributors to PAHs and SPAHs. The risk level of PAHs was low-to-moderate, while SPAHs posed a moderate-to-high ecological risk.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Organic
Yan-Ying Wu, Yi-Lin Wu, Cheng-Lan Lin, Hung-Cheng Chen, Yao-Yuan Chuang, Chih-Hsien Chen, Chih-Ming Chou
Summary: A strategy for the synthesis of dibenz-[a,j]-anthracenes (DBAs) from cyclohexa-2,5-diene-1-carboxylic acids is presented. The method involves sequential C-H olefination, cycloaddition, and decarboxylative aromatization, leading to regioselective ring formation and functional group introduction.
Article
Chemistry, Organic
Tomer Weiss, Alexandra Wahab, Alex M. Bronstein, Renana Gershoni-Poranne
Summary: In this study, interpretable deep learning was used to identify the structure-property relationships of polybenzenoid hydrocarbons (PBHs) using a ring-based graph representation. The results showed agreement with conventional organic chemistry knowledge and electronic structure-based analyses, while also revealing new behaviors and influential structural motifs. The effects of linear, angular, and branching motifs on molecular properties were evaluated and compared, and the role of dispersion in mitigating torsional strain in nonplanar PBHs was explored. These findings contribute to a deeper understanding of PBH behavior and provide a foundation for designing new functional PBHs.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Komal Mittal, Ashley V. Pham, Amanda G. Davis, Abigail D. Richardson, Clement De Hoe, Ryan T. Dean, Vi Baird, Ashley Ringer McDonald, Derik K. Frantz
Summary: At elevated temperatures, a strained, cyclic meta-quaterphenylene acetylene undergoes an intramolecular cyclization reaction to form benz[e]indeno[1,2,3-hi]acephenanthrylene. This reaction represents a Diels-Alder reaction at the 2-, 1-, 1 '-, and 2 '-positions of a biphenyl derivative, similar to the bay regions of perylene and other periacenes. Kinetics studies reveal that the reaction has a similar energy barrier to a concerted [4 + 2]-cycloaddition.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
