Article
Microbiology
Rafael Gariglio Clark Xavier, Clarissa Helena Santana, Paloma Helena Sanches da Silva, Flavia Figueira Aburjaile, Felipe Luiz Pereira, Henrique Cesar Pereira Figueiredo, Patricia Maria Coletto Freitas, Renato Lima Santos, Rodrigo Otavio Silveira Silva
Summary: This study investigated the simultaneous occurrence of pyometra and Escherichia coli in two cohabitant female dogs. It suggested the first transmission of E. coli associated with pyometra between two animals, which could impact the management of sites where several females cohabit.
Review
Immunology
Jonathan Josephs-Spaulding, Thoger Jensen Krogh, Hannah Clara Rettig, Mark Lyng, Mariam Chkonia, Silvio Waschina, Simon Graspeuntner, Jan Rupp, Jakob Moller-Jensen, Christoph Kaleta
Summary: This article discusses the ecological interactions of human urogenital microbial communities, the mechanism of imbalance between microbial ecology and host physiology. A greater understanding of environmental mechanisms and microbial ecology is needed for the treatment and management of UTIs. The use of next generation and systems level methods is recommended to elucidate the systemic consequences of rUTIs.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Microbiology
Jullia A. S. Nascimento, Fernanda F. Santos, Tiago B. Valiatti, Jose F. Santos-Neto, Ana Carolina M. Santos, Rodrigo Cayo, Ana C. Gales, Tania A. T. Gomes
Summary: This study identified 9 out of 452 UPEC strains (2%) as hybrid strains, with 7 classified as UPEC/EAEC and 2 as UPEC/aEPEC. These hybrid strains displayed specific characteristics in terms of cell adhesion ability and virulence potential.
Article
Microbiology
Jullia A. S. Nascimento, Fernanda F. Santos, Jose F. Santos-Neto, Liana O. Trovao, Tiago B. Valiatti, Isabel C. Pinaffi, Monica A. M. Vieira, Rosa M. Silva, Ivan N. Falsetti, Ana C. M. Santos, Tania A. T. Gomes
Summary: This study evaluated E. coli isolates from 172 outpatient with UTI and found that phylogroup B2 strains were predominant, along with the presence of various virulence factors associated with diarrheagenic and extraintestinal pathogenic E. coli. Some strains showed uropathogenic potential, including a few classified as hybrid strains. These hybrid strains interacted with renal and bladder cells, highlighting their uropathogenic capabilities.
Article
Microbiology
Nicolas Vautrin, Kevin Alexandre, Martine Pestel-Caron, Estelle Bernard, Roland Fabre, Marie Leoz, Sandrine Dahyot, Francois Caron
Summary: Recurrent cystitis is a common disease in women, mainly caused by uropathogenic Escherichia coli. Our study demonstrates the importance of personalized treatment and prevention for cystitis.
MICROBIOLOGY SPECTRUM
(2023)
Article
Infectious Diseases
Sophia Hawas, Jilong Qin, Sandra Wiedbrauk, Kathryn Fairfull-Smith, Makrina Totsika
Summary: Urinary tract infections (UTIs) are common bacterial infections with high recurrence rates. In this study, a new therapeutic compound was evaluated in multiple preclinical models and showed promising antibiofilm activity.
Article
Medicine, General & Internal
Katarina Mestrovic Popovic, Petra Povalej Brzan, Tomaz Langerholc, Natasa Marcun Varda
Summary: Probiotics may be helpful in alleviating UTI symptoms and preventing UTI recurrence.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Zhengdong Gao, Yaxiao Liu, Lekai Zhang, Zizhuo Yang, Linchen Lv, Shuai Wang, Lipeng Chen, Nan Zhou, Yaofeng Zhu, Xuewen Jiang, Benkang Shi, Yan Li
Summary: This study explores the interaction between nociceptor neurons and the bladder immune system during urinary tract infections (UTIs). The researchers found that uropathogenic Escherichia coli (UPEC) and its pathogenic factor directly stimulate nociceptor neurons, causing the neurons to release calcitonin gene-related peptide (CGRP) and suppress immune responses. By blocking neuronal inhibition, UTI can be prevented.
JOURNAL OF INFLAMMATION RESEARCH
(2022)
Article
Microbiology
Manuel G. Ballesteros-Monrreal, Margarita M. P. Arenas-Hernandez, Edwin Barrios-Villa, Josue Juarez, Maritza Lizeth alvarez-Ainza, Pablo Taboada, Rafael de la Rosa-lopez, Enrique Bolado-Martinez, Dora Valencia
Summary: Urinary tract infections caused by Uropathogenic Escherichia coli in women in Sonora, Mexico show diverse bacterial morphotypes, virulence genes, and phenotypes, with high resistance to various antibiotics. The presence of morphotypes in urine sediment is crucial in urine analysis, and the clinical isolates of UPEC in this study have the potential to cause different types of UTIs.
Article
Microbiology
Mykhailo Savin, Gabriele Bierbaum, Judith Kreyenschmidt, Ricarda Maria Schmithausen, Esther Sib, Silvia Schmoger, Annemarie Kaesbohrer, Jens Andre Hammerl
Summary: Escherichia coli with high multidrug resistance rates and extraintestinal pathogenic potential were found in poultry and pig slaughterhouses in Germany. The isolates were reservoirs for numerous antimicrobial resistance determinants and contained high-risk clones associated with human infections worldwide. The presence of uropathogenic E. coli in the effluent of a poultry slaughterhouse's wastewater treatment plant suggests potential dissemination into surface waters.
Article
Medicine, General & Internal
Xiao Li, Kaichen Zhou, Jingyu Wang, Jiahe Guo, Yang Cao, Jie Ren, Tao Guan, Wenchao Sheng, Mingyao Zhang, Zhi Yao, Quan Wang
Summary: Urinary tract infections (UTIs) are common infectious diseases caused by uropathogenic Escherichia coli (UPEC). By analyzing the distribution patterns of fimbrial genes in UPEC strains using PCR, it was found that these patterns could predict the localization of upper and lower UTIs. This has significant implications for predicting UTIs based on fimbrial gene distribution.
FRONTIERS IN MEDICINE
(2021)
Article
Materials Science, Biomaterials
Anthony J. Kyser, Mohamed Y. Mahmoud, Nicholas T. Johnson, Bassam Fotouh, Jill M. Steinbach-Rankins, Nicole M. Gilbert, Hermann B. Frieboes
Summary: Catheter-associated urinary tract infections (CAUTI) are a significant healthcare burden. This study demonstrates the potential use of 3D bioprinting to create silicone catheters containing probiotic lactobacilli, which can release active compounds and potentially prevent or treat CAUTI.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Review
Infectious Diseases
Yveline Ansaldi, Begona Martinez de Tejada Weber
Summary: Urinary tract infections (UTIs) during pregnancy can have significant consequences for both the mother and the baby. Treating asymptomatic bacteriuria (ASB) can reduce the risk of low birth weight and preterm birth. Further research is needed to understand the complications of ASB and to explore preventive measures.
CLINICAL MICROBIOLOGY AND INFECTION
(2023)
Article
Urology & Nephrology
Monique H. Vaughan, Jialiang Mao, Lisa A. Karstens, Li Ma, Cindy L. Amundsen, Kenneth E. Schmader, Nazema Y. Siddiqui
Summary: The study found associations between anaerobic bacteria in the urinary microbiome and postmenopausal recurrent UTI, suggesting a need for further investigation.
JOURNAL OF UROLOGY
(2021)
Review
Medicine, General & Internal
Raymond Xu, Nicholas Deebel, Randy Casals, Rahul Dutta, Majid Mirzazadeh
Summary: Urinary tract infections are common in the United States and incur significant healthcare costs. The standard urine culture for diagnosis has limitations, leading to the development of new techniques like PCR and NGS. Further evaluation is needed to determine if these new tests can replace the traditional urine culture method.
Letter
Hematology
Julien Coussement, Julien De Greef, Amelie Dureault, David Lebeaux
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
(2018)
Article
Immunology
Amelie Heinrichs, Maria Angeles Argudin, Ricardo De Mendonca, Ariane Deplano, Sandrine Roisin, Magali Dodemont, Julien Coussement, Lorenzo Filippin, Jill Dombrecht, Katrien De Bruyne, Te-Din Huang, Philip Supply, Baudouin Byl, Youri Glupczynski, Olivier Denis
CLINICAL INFECTIOUS DISEASES
(2019)
Article
Infectious Diseases
F. Lopez-Medrano, M. Fernandez-Ruiz, J. T. Silva, P. L. Carver, C. van Delden, E. Merino, M. J. Perez-Saez, M. Montero, J. Coussement, M. de Abreu Mazzolin, C. Cervera, L. Santos, N. Sabe, A. Scemla, E. Cordero, L. Cruzado-Vega, P. L. Martin-Moreno, O. Len, E. Rudas, A. Ponce de Leon, M. Arriola, R. Lauzurica, M. D. David, C. Gonzalez-Rico, F. Henriquez-Palop, J. Fortun, M. Nucci, O. Manuel, R. Pano-Pardo, M. Montejo, A. Vena, B. Sanchez-Sobrino, A. Mazuecos, J. Pascual, J. P. Horcajada, T. Lecompte, A. Moreno, J. Carratala, M. Blanes, D. Hernandez, E. A. Hernandez-Mendez, M. C. Farinas, M. Perello-Carrascosa, P. Munoz, A. Andres, J. M. Aguado
CLINICAL MICROBIOLOGY AND INFECTION
(2018)
Article
Multidisciplinary Sciences
Julien Coussement, David Lebeaux, Najla El Bizri, Vincent Claes, Michel Kohnen, Deborah Steensels, Isabelle Etienne, Helene Salord, Emmanuelle Bergeron, Veronica Rodriguez-Nava
Letter
Immunology
Julien Coussement, Anne Scemla, Daniel Abramowicz, Evi V. Nagler, Angela C. Webster
CLINICAL INFECTIOUS DISEASES
(2020)
Article
Immunology
Blandine Rammaert, Mathieu Puyade, Oliver A. Cornely, Danila Seidel, Paolo Grossi, Shahid Husain, Clement Picard, Cornelia Lass-Floerl, Oriol Manuel, Jerome Le Pavec, Olivier Lortholary, Claudia Nagel, Glen Westall, Orla Morrissey, Daniel Chambers, Stephan Eschertzhuber, Julien Coussement, ChristianeKnoop, Robin Vos, Lieven Dupont, Michel Dumonceaux, Silvia Vidal Campos, Dima Kabbani, Carlos Cervera, Me-Linh Luong, Elodie Blanchard, Agathe Senechal, Olivier Brugiere, Veronique Boussaud, Romain Guillemain, Jean-Francois Bervar, Johanna Claustre, Alain Haloun, Sandrine Hirschi, Martine Reynaud, Nikolaus Kneidinger, Jens Gottlieb, Emmanuel Roilides, Hossein Zarrinfar, Lorenzo Rosso, Letizia Corinna Morlacchi, Andrea Dell'Amore, Monica Loy, Claudy Oliveira dos Santos, JordiRello, Victor Monforte, Maria Teresa Martin-Gomez, Francisco Lopez Medrano, Mario Fernandez-Ruiz, Amparo Sole, Jose M. Cifrian, Dionysios Neofytos, Nicolas Mueller, Christian Benden, Anne Kathrin Brill, Esen Kiyan, Kate Gould, Effrossyni Gkrania-Klotsas, Miruna David, Sam Weigt, Eun Jeong Kwak, Femanda Silveira, Denis Hadjiliadis, John Baddley, Lara Danziger-Isakov, Sangeeta Bhorade, Michael Ison, Cameron Wolfe, Saima Aslam, Marie Budem, Ana Musetti
TRANSPLANT INFECTIOUS DISEASE
(2019)
Article
Immunology
Daniel Shepshelovich, Noam Tau, Hefziba Green, Benaya Rozen-Zvi, Assaf Issaschar, Marco Falcone, Julien Coussement, Oren Zusman, Oriol Manuel, Eytan Mor, Julian Torre-Cisneros, Dafna Yahav
TRANSPLANT INFECTIOUS DISEASE
(2019)
Article
Multidisciplinary Sciences
Julien Coussement, Anne Scemla, Jean-Michel Hougardy, Rebecca Sberro-Soussan, Lucile Amrouche, Concetta Catalano, James R. Johnson, Daniel Abramowicz
Article
Surgery
Elena Perez-Nadales, Belen Gutierrez-Gutierrez, Alejandra M. Natera, Edson Abdala, Maira Reina Magalhaes, Alessandra Mularoni, Francesco Monaco, Ligia Camera Pierrotti, Maristela Pinheiro Freire, Ranganathan N. Iyer, Seema Mehta Steinke, Elisa Grazia Calvi, Mario Tumbarello, Marco Falcone, Mario Fernandez-Ruiz, Jose Maria Costa-Mateo, Meenakshi M. Rana, Tania Mara Varejao Strabelli, Mical Paul, Maria Carmen Farinas, Wanessa Trindade Clemente, Emmanuel Roilides, Patricia Munoz, Laurent Dewispelaere, Belen Loeches, Warren Lowman, Ban Hock Tan, Rosa Escudero-Sanchez, Marta Bodro, Paolo Antonio Grossi, Fabio Soldani, Filiz Gunseren, Nina Nestorova, Alvaro Pascual, Luis Martinez-Martinez, Jose Maria Aguado, Jesus Rodriguez-Bano, Julian Torre-Cisneros, A. T. Wan Song, W. Andraus, L. A. Carneiro D'Albuquerque, E. David-Neto, F. Jota de Paula, F. Rossi, D. Ostrander, R. Avery, M. Rizzi, A. R. Losito, F. Raffaelli, P. Del Giacomo, G. Tiseo, J. Lora-Tamayo, R. San-Juan, I Gracia-Ahufinger, J. Caston, Y. A. Ruiz, D. R. Altman, S. Campos, N. Bar-Sinai, F. Koppel, F. Arnaiz de las Revillas Almajano, C. Gonzalez Rico, M. Fernandez Martinez, P. H. O. Mourao, F. A. Neves, J. Ferreira, A. Pyrpasopoulou, E. Iosifidis, I Romiopoulos, M. Minero, C. Sanchez-Carrillo, S. Lardo, J. Coussement, M. Dodemont, K. Jiayun, P. Martin-Davila, J. Fortun, M. Almela, A. Moreno, L. Linares, D. D. Gasperina, M. L. Balsamo, C. Rovelli, E. Concia, S. Chiesi, D. N. Salerno, D. Ogunc, B. Pilmis, E. M. Seminari, J. Carratala, A. Dominguez, E. Cordero, J. A. Lepe, M. Montejo, E. Merino de Lucas, B. M. Eriksson, C. van Delden, O. Manuel, H. Arslan, Z. Kocak Tufan, E. Kazak, M. David, E. Lease, G. Cornaglia, M. Akova
AMERICAN JOURNAL OF TRANSPLANTATION
(2020)
Letter
Immunology
Julien Coussement, Oriol Manuel
CLINICAL INFECTIOUS DISEASES
(2021)
Editorial Material
Transplantation
Julien Coussement, Nassim Kamar, Daniel Abramowicz
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Review
Hematology
Joanne S. K. Teh, Julien Coussement, Zoe C. F. Neoh, Tim Spelman, Smaro Lazarakis, Monica A. Slavin, Benjamin W. Teh
Summary: This study assessed the immunogenicity and safety of COVID-19 vaccines in patients with hematologic malignancies. The results showed that the seropositivity rates after 2 doses of COVID-19 vaccine were 62% to 66%, and after 1 dose were 37% to 51%. The neutralizing antibody response rates were 57% to 60%, and cellular response rates were 40% to 75%. Active treatment, ongoing or recent treatment with targeted therapies were associated with poor immune responses to COVID-19 vaccine.
Editorial Material
Immunology
Julien Coussement, Matthieu Lafaurie
TRANSPLANT INFECTIOUS DISEASE
(2023)
Review
Medicine, General & Internal
Julien Coussement, Anne Scemla, Daniel Abramowicz, Evi V. Nagler, Angela C. Webster
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2018)