Programmed necrosis in acute kidney injury

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

(2012) Zhigao Wang et al.   CELL

Inhibition of glycogen synthase kinase-3β prevents NSAID-induced acute kidney injury

(2012) Hao Bao et al.   KIDNEY INTERNATIONAL

A possible mechanism of renal cell death after ischemia/reperfusion

(2012) Peter M. Price et al.   KIDNEY INTERNATIONAL

Poly(ADP-ribose) polymerase 1 activation is required for cisplatin nephrotoxicity

(2012) Jinu Kim et al.   KIDNEY INTERNATIONAL

Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

(2012) Andreas Linkermann et al.   KIDNEY INTERNATIONAL

Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

(2012) Vincenzo Cantaluppi et al.   KIDNEY INTERNATIONAL

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nec-1 Protects against Nonapoptotic Cell Death in Cisplatin-Induced Kidney Injury

(2012) Vivian Regina Tristão et al.   RENAL FAILURE

Proliferative versus apoptotic functions of caspase-8

(2011) Bram J. van Raam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation

(2011) L Cabon et al.   CELL DEATH AND DIFFERENTIATION

Many stimuli pull the necrotic trigger, an overview

(2011) N Vanlangenakker et al.   CELL DEATH AND DIFFERENTIATION

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

(2011) Navjotsingh Pabla et al.   JOURNAL OF CLINICAL INVESTIGATION

TWEAK, a multifunctional cytokine in kidney injury

(2011) Ana Belen Sanz et al.   KIDNEY INTERNATIONAL

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

(2011) Maria Feoktistova et al.   MOLECULAR CELL

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

(2011) Tencho Tenev et al.   MOLECULAR CELL

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

(2011) William J. Kaiser et al.   NATURE

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

(2011) Andrew Oberst et al.   NATURE

Linear ubiquitination prevents inflammation and regulates immune signalling

(2011) Björn Gerlach et al.   NATURE

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival

(2011) Andrew Oberst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Emerging Role of Linear Ubiquitination in Cell Signaling

(2011) C. H. Emmerich et al.   Science Signaling

Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis

(2010) Craig Brooks et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Going up in flames: necrotic cell injury and inflammatory diseases

(2010) Sreerupa Challa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Necroptosis as an alternative form of programmed cell death

(2010) Dana E Christofferson et al.   CURRENT OPINION IN CELL BIOLOGY

Effective Blockage of Both the Extrinsic and Intrinsic Pathways of Apoptosis in Mice by TAT-crmA

(2010) Stefan Krautwald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKC-  Promotes Renal Tubular Cell Apoptosis Associated with Proteinuria

(2010) X. Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TWEAK–Fn14 as a mediator of acute kidney injury

(2010) Joel M. Weinberg   KIDNEY INTERNATIONAL

Am I my brother's keeper?: fratricide in the kidney

(2010) Robert L. Safirstein   KIDNEY INTERNATIONAL

Direct targeting of fibroblast growth factor-inducible 14 protein protects against renal ischemia reperfusion injury

(2010) Kiyohiko Hotta et al.   KIDNEY INTERNATIONAL

Renal tubular Fas ligand mediates fratricide in cisplatin-induced acute kidney failure

(2010) Andreas Linkermann et al.   KIDNEY INTERNATIONAL

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

(2010) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

(2010) G. Trichonas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

(2009) Craig Brooks et al.   JOURNAL OF CLINICAL INVESTIGATION

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Inhibition of JAK2 protects renal endothelial and epithelial cells from oxidative stress and cyclosporin A toxicity

(2008) Fernando Neria et al.   KIDNEY INTERNATIONAL

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE