Article
Transplantation
Aarti Mathur, JiYoon B. Ahn, Whitney Sutton, Nadia M. Chu, Alden L. Gross, Dorry L. Segev, Mara McAdams-DeMarco
Summary: Receiving treatment for secondary hyperparathyroidism (SHPT) was associated with a lower risk of incident dementia among older patients with end-stage renal disease (ESRD). The beneficial effect of SHPT treatment differed by sex and race, with females and those of Asian or Black race experiencing the greatest reduction in dementia risk.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Endocrinology & Metabolism
Chieh-Li Yen, Pei-Chun Fan, Ming-Shyan Lin, Cheng-Chia Lee, Kun-Hua Tu, Chao-Yu Chen, Ching-Chung Hsiao, Hsiang-Hao Hsu, Ya-Chung Tian, Chih-Hsiang Chang
Summary: This study found that among advanced CKD patients, the use of fenofibrate and statins can reduce the risk of cardiovascular death, while fenofibrate can also reduce the incidence of permanent dialysis.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Urology & Nephrology
Julien Prouvot, Emilie Pambrun, Valery Antoine, Cecile Couchoud, Cecile Vigneau, Sophie Roche, Maud Francois, Christophe Mariat, Daniela Babici, Camelia Prelipcean, Olivier Moranne, Pspa Investigators
Summary: The study evaluated existing prognostic scores for predicting death in elderly CKD patients before initiating dialysis, and found that the available scores showed low performance in a French multicentre cohort, indicating the need to upgrade or develop new scores for this population.
JOURNAL OF NEPHROLOGY
(2022)
Article
Urology & Nephrology
Julien Prouvot, Emilie Pambrun, Cecile Couchoud, Cecile Vigneau, Sophie Roche, Vincent Allot, Jerome Potier, Maud Francois, Daniela Babici, Camelia Prelipcean, Olivier Moranne
Summary: Evaluating existing risk model scores predicting end stage renal disease (ESRD) in a cohort of octogenarian patients with advanced chronic kidney disease (CKD) showed poor performance, highlighting the necessity for developing new tools for this population.
JOURNAL OF NEPHROLOGY
(2021)
Article
Transplantation
Victor Fages, Natalia Alencar de Pinho, Aghiles Hamroun, Celine Lange, Christian Combe, Denis Fouque, Luc Frimat, Christian Jacquelinet, Maurice Laville, Carole Ayav, Sophie Liabeuf, Roberto Pecoits-Filho, Ziad A. Massy, Julie Boucquemont, Benedicte Stengel
Summary: This study identifies important patient- and provider-level factors that are associated with urgent-start dialysis, highlighting the need to address these factors to reduce the burden of urgent dialysis initiation.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Urology & Nephrology
Chi D. Chu, Charles E. Mcculloch, Raymond K. Hsu, Neil R. Powe, Brian Bieber, Bruce M. Robinson, Rupesh Raina, Roberto Pecoits-Filho, Delphine S. Tuot
Summary: The Kidney Failure Risk Equation (KFRE) can predict the risk of kidney failure for patients with chronic kidney disease (CKD), and translating this prediction into time can help inform decision making for patients approaching kidney failure.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2023)
Review
Urology & Nephrology
David E. St-Jules, Mary R. Rozga, Deepa Handu, Juan Jesus Carrero
Summary: The study evaluated the effect of phosphate-specific diet therapy provided by a dietitian on serum phosphate in patients on HD. The results showed that diet therapy effectively reduced serum phosphate levels, but the overall certainty of evidence was low.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Nutrition & Dietetics
Keizo Nishime, Noriko Sugiyama, Koichi Okada
Summary: Analysis of test values of 48 patients in 2019 showed that the adequate range rates were 70.8% for P, 100% for cCa, and 89.6% for w-PTH, which were better than the JSDT standard. The discrepancy between processed foods with P additives and treatment methods may lead to challenges in reaching adequate levels for CKD-MBD treatment.
Article
Urology & Nephrology
Chi D. Chu, Neil R. Powe, Deidra C. Crews, Delphine S. Tuot
Summary: This study compares the time to kidney failure with replacement therapy among Black, Hispanic, and White patients, and assesses the impact of incorporating race into the estimation of glomerular filtration rate on waitlist eligibility and time to kidney failure. The results show that Black and Hispanic patients have less opportunity to be placed on the transplant waitlist compared to White patients. For many Black patients, estimating the filtration rate as if their race were non-Black could allow for earlier waitlisting.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Urology & Nephrology
Elizabeth R. Stremke, Gretchen N. Wiese, Sharon M. Moe, Meryl E. Wastney, Ranjani N. Moorthi, Kathleen M. Hill Gallant
Summary: This study showed that there was no significant difference in fractional intestinal phosphorus absorption between patients with moderate CKD and healthy adults, despite lower levels of serum 1,25D. Additionally, the relationship between fractional intestinal phosphorus absorption and 24-hour urine phosphorus was not evident.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Urology & Nephrology
James B. Wetmore, Yuanyuan Ji, Akhtar Ashfaq, David T. Gilbertson, Nicholas S. Roetker
Summary: Analysis of electronic health records of over 50 million patients revealed suboptimal frequency of post-treatment retesting for CKD-MBD patients. Some patients did not undergo necessary testing after treatment, and pretreatment levels of PTH and 25D were not directly associated with likelihood of retesting.
KIDNEY INTERNATIONAL REPORTS
(2021)
Article
Urology & Nephrology
Jia Zhang, Chris H. L. Thio, Ron T. Gansevoort, Harold Snieder
Summary: This study showed that a positive family history was strongly associated with increased risk of CKD. Genetic factors play an important role in the risk of kidney disease. There is moderate to high heritability of kidney traits and related biomarkers.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)
Article
Nutrition & Dietetics
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Kook-Hwan Oh, Young Youl Hyun, Suah Sung, Soo Wan Kim
Summary: The relationship between 24-h urinary phosphorus excretion (24 h UPE) and cardiovascular disease in pre-dialysis CKD patients is not well-studied. This study found that low 24 h UPE is associated with adverse cardiovascular outcomes in CKD patients, indicating that it should not be relied upon as a marker for dietary phosphorus restriction.
Article
Urology & Nephrology
Guoxin Ye, Wei Yang, Zhaori Bi, Liya Huang, Fang Liu
Summary: High-phosphorus diets were found to alter gut microbiota and elevate systolic blood pressure in healthy rats and chronic kidney disease rats, potentially leading to adverse long-term health outcomes.
Article
Medicine, General & Internal
Shina Lee, Seung-Jung Kim
Summary: Serum levels of phosphorus and intact parathyroid hormone (iPTH) are associated with endothelial dysfunction, even in CKD patients with normal phosphorus levels.
FRONTIERS IN MEDICINE
(2022)