Article
Polymer Science
Paul J. Besseling, Tristan Mes, Anton W. Bosman, Joris W. Peeters, Henk M. Janssen, Maarten H. Bakker, Joost O. Fledderus, Martin Teraa, Marianne C. Verhaar, Hendrik Gremmels, Patricia Y. W. Dankers
Summary: Supramolecular biomaterials based on ureido-pyrimidinone (UPy) moieties are versatile polymer materials that can be tailored to various applications with good biocompatibility and solubility, showing potential for use in regenerative medicine and biomedical fields.
JOURNAL OF POLYMER SCIENCE
(2021)
Article
Chemistry, Applied
Hui Shi, Liu Hong, Kai Pan, Wei Wei, Xiaoya Liu, Xiaojie Li
Summary: The study introduces a biodegradable polyacrylate copolymer coating to enhance the corrosion resistance and biocompatibility of magnesium alloys. The coating significantly reduces the corrosion rate and improves the cytocompatibility of the alloy.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Chemistry, Analytical
Aiganym Yermembetova, Muhammed Ramazan Oduncu, Alexander Wei
Summary: Thin-film pH electrodes on thermoplastic substrates can withstand high doses of gamma radiation while maintaining stability and sensing performance, which is important for monitoring analytes in sterile environments.
ANALYTICAL CHEMISTRY
(2022)
Article
Cell & Tissue Engineering
Henry Chen, Devendra K. Agrawal, Finosh G. Thankam
Summary: Understanding the novel concept of biomaterials-driven sterile inflammation and associated damage-associated molecular patterns in long-term biodegradable implants would determine their success and improve the tissue engineering and regenerative strategies.
TISSUE ENGINEERING PART B-REVIEWS
(2022)
Article
Polymer Science
Greta Biale, Jacopo La Nasa, Marco Mattonai, Andrea Corti, Virginia Vinciguerra, Valter Castelvetro, Francesca Modugno
Summary: The study analyzed the degradation processes of naturally photo-aged microplastic particles in the environment, revealing the generation of extractable low molecular weight products during photo-degradation. Different types of polymers produced different types of degradation products during the degradation process.
Article
Nutrition & Dietetics
Jose Maria Moreno-Navarrete, Jessica Latorre, Aina Lluch, Francisco J. Ortega, Ferran Comas, Maria Arnoriaga-Rodriguez, Wifredo Ricart, Jose Manuel Fernandez-Real
Summary: Plasma lysozyme levels and activity are significantly increased in obese subjects, directly associated with obesity-related metabolic disturbances and inflammatory parameters. The longitudinal findings suggest that plasma lysozyme may have a protective role in the development of obesity-associated metabolic disturbances.
CLINICAL NUTRITION
(2021)
Article
Engineering, Biomedical
Yingchao Su, Jiayin Fu, Wonsae Lee, Shaokang Du, Yi-Xian Qin, Yufeng Zheng, Yadong Wang, Donghui Zhu
Summary: The study found that alloying zinc with iron significantly improves its mechanical property and facilitates uniform degradation, enhancing its biocompatibility, especially the Zn-0.4Fe alloy. Moreover, these Zn-Fe alloys exhibit outstanding antibacterial property, making them promising candidates for bioresorbable medical implants in various applications such as cardiovascular, wound closure, and orthopedics.
BIOACTIVE MATERIALS
(2022)
Article
Engineering, Biomedical
Malgorzata Sikora-Jasinska, Lea M. Morath, Maria P. Kwesiga, Margaret E. Plank, Alexia L. Nelson, Alexander A. Oliver, Martin L. Bocks, Roger J. Guillory, Jeremy Goldman
Summary: The study evaluated the mechanical performance and biodegradation properties of metallic molybdenum (Mo) as a potential material for biodegradable stents. The results showed favorable mechanical behavior and uniform degradation profile, suggesting Mo as an ideal source material for clinical applications. Mo implants in mouse arteries avoided cellular response and showed minimal neointimal hyperplasia, indicating good biocompatibility. However, potential pathological remodeling and impaired kidney function were observed, suggesting further investigation is needed.
BIOACTIVE MATERIALS
(2022)
Article
Biology
Anna Isabell Weaver, Laura Alvarez, Kelly M. Rosch, Asraa Ahmed, Garrett Sean Wang, Michael S. van Nieuwenhze, Felipe Cava, Tobias Dorr
Summary: The peptidoglycan cell wall is a crucial structure for bacteria, with the ability to determine cell shape and support survival. Peptidoglycan is a dynamic process that requires regulated synthesis and turnover. This study uncovers the physiological role of lytic transglycosylases (LTGs), a class of autolytic enzymes, and demonstrates their essentiality for bacterial survival. The study also suggests that LTGs prevent toxic accumulation of peptidoglycan polymers and their function is independent of peptidoglycan synthesis.
Article
Materials Science, Biomaterials
Lukas Benecke, Zhaoyu Chen, Ines Zeidler-Rentzsch, Max von Witzleben, Matthias Bornitz, Thomas Zahnert, Marcus Neudert, Chokri Cherif, Dilbar Aibibu
Summary: In this study, biomimetic synthetic TM implants were developed using electrospinning technology, overcoming the limitations of autologous grafts and exhibiting comparable acousto-mechanical properties to human TMs.
BIOMATERIALS SCIENCE
(2022)
Article
Chemistry, Physical
Mariel G. Tecson, Drexel H. Camacho, Virgilio D. Ebajo, Lucille Abad
Summary: The production of low-molecular-weight x-carrageenan by irradiation has been shown to enhance plant growth and stimulate defense action in various crops. This study investigated the structural changes in irradiated x-carrageenan, providing insights into the structure-activity relationship. Spectroscopic techniques revealed that irradiation led to degradation of x-carrageenan and formation of new chemical structures.
RADIATION PHYSICS AND CHEMISTRY
(2022)
Article
Polymer Science
Xiaoxia Fan, Sudi Zhu, Lin Yan, Hui Zhu
Summary: Reactive oxygen species-responsive degradable poly(amino acid)s were synthesized via in situ melting polycondensation and characterized. The incorporation of methionine was found to affect the thermal stability, degradation behavior, and mechanical properties of the PAAs. These PAAs showed promising biocompatibility and degradation properties, making them potential candidates for high-performance biomedical applications.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Nga T. N. Vo, Lei Huang, Henrique Lemos, Andrew L. Mellor, Katarina Novakovic
Summary: Genipin-crosslinked chitosan hydrogels show promising biocompatibility and potential as vaccine carriers. Addition of poly (ethylene glycol) enhances cytocompatibility and delays degradation of the hydrogels.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Chemistry, Analytical
Noah M. Froelich, Rachel E. Showerman, Andres D. Campiglia
Summary: The increasing accessibility of 3D printers increases the likelihood of their use for criminal activity. Current forensic analysis focuses on identifying the general type of plastic used in 3D printing, but this study presents a nondestructive approach that can differentiate between different types of nylons.
ANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Composites
Sivagnanamani Gnanamani Sankaravel, Rashia Begum Syed, Vasumathi Manivachakan
Summary: This research focused on the utilization of natural biomaterial egg shell particles (ESP) as a filler material in PLA composite scaffolds. The study found that an increase in filler particles led to a significant reduction in water contact angle, and the performance varied at different filling percentages and porosities.
POLYMER COMPOSITES
(2022)
Article
Endocrinology & Metabolism
Axel Guilbaud, Michael Howsam, Celine Niquet-Leridon, Florian Delguste, Eric Boulanger, Frederic J. Tessier
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2019)
Review
Geriatrics & Gerontology
Thibault Teissier, Eric Boulanger
Article
Food Science & Technology
Axel Guilbaud, Michael Howsam, Celine Niquet-Leridon, Florian Delguste, Marc Fremont, Sophie Lestavel, Patrice Maboudou, Anne Garat, Susanna Schraen, Brigitte Onraed, Benoit Foligne, Eric Boulanger, Frederic J. Tessier
MOLECULAR NUTRITION & FOOD RESEARCH
(2020)
Article
Nutrition & Dietetics
Fritz Line Velayoudom-Cephise, Mariola Cano-Sanchez, Sylvie Bercion, Frederic Tessier, Yichi Yu, Eric Boulanger, Remi Neviere
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2020)
Review
Clinical Neurology
T. Teissier, E. Boulanger, V Deramecourt
REVUE NEUROLOGIQUE
(2020)
Review
Geriatrics & Gerontology
Aurelie Mailliez, Axel Guilbaud, Francois Puisieux, Luc Dauchet, Eric Boulanger
EXPERIMENTAL GERONTOLOGY
(2020)
Review
Biochemistry & Molecular Biology
Frederic J. Tessier, Eric Boulanger, Michael Howsam
Summary: The Maillard reaction is a major chemical reaction responsible for most yellow-to-brown colors and aromas in cooked foods, leading to the formation of structurally-modified amino acids. High or chronic exposure to dietary AGEs may be potentially detrimental to human health, prompting research in food safety to focus on the metabolic transit of AGEs.
GLYCOCONJUGATE JOURNAL
(2021)
Article
Medicine, General & Internal
Gregory Mansella, Marco Rueegg, Andreas F. Widmer, Sarah Tschudin-Sutter, Manuel Battegay, Julia Hoff, Kirstine K. Sogaard, Adrian Egli, Bram Stieltjes, Karoline Leuzinger, Hans H. Hirsch, Andrea Meienberg, Thilo Burkard, Michael Mayr, Roland Bingisser, Christian H. Nickel
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Endocrinology & Metabolism
Elodie Lespagnol, Semah Tagougui, Bernadette O. Fernandez, Farid Zerimech, Regis Matran, Patrice Maboudou, Serge Berthoin, Amandine Descat, Isabelle Kim, Mehdi Pawlak-Chaouch, Julien Boissiere, Eric Boulanger, Martin Feelisch, Pierre Fontaine, Elsa Heyman
Summary: This study found that individuals with type 1 diabetes exhibit compromised endothelial function during physical exercise, possibly due to alterations in nitric oxide formation or metabolism. Despite lower availability of NO-related substrates, oxidative stress did not worsen, and differences in habitual physical activity levels between participants did not impact the results.
Article
Biochemistry & Molecular Biology
Olivia May, Laure Yatime, Nicolas S. Merle, Florian Delguste, Mike Howsam, Marie Daugan, Charles Paul-Constant, Muriel Billamboz, Alina Ghinet, Steve Lancel, Jordan D. Dimitrov, Eric Boulanger, Lubka T. Roumenina, Marie Frimat
Summary: The interaction between RAGE and heme with micromolar affinity could potentially promote proinflammatory and prothrombotic signaling in vivo. This suggests that this interaction may play a role in heme-overload conditions.
Article
Urology & Nephrology
Julien Prouvot, Emilie Pambrun, Cecile Couchoud, Cecile Vigneau, Sophie Roche, Vincent Allot, Jerome Potier, Maud Francois, Daniela Babici, Camelia Prelipcean, Olivier Moranne
Summary: Evaluating existing risk model scores predicting end stage renal disease (ESRD) in a cohort of octogenarian patients with advanced chronic kidney disease (CKD) showed poor performance, highlighting the necessity for developing new tools for this population.
JOURNAL OF NEPHROLOGY
(2021)
Review
Medicine, Research & Experimental
Axel Guilbaud, Aurelie Mailliez, Eric Boulanger
M S-MEDECINE SCIENCES
(2020)
Article
Geriatrics & Gerontology
Frederic N. Daussin, Eric Boulanger, Steve Lancel
Summary: Sarcopenia is characterized by muscle mass and function loss, with mitochondrial alterations considered a key contributor. The pro-inflammatory receptor RAGE is involved in inflammaging and may have a connection with mitochondria in controlling sarcopenia.
EXPERIMENTAL GERONTOLOGY
(2021)
Article
Geriatrics & Gerontology
Dominique Huvent-Grelle, Gregoire Ficheur, Jean Baptiste Beuscart, Michael Genin, Claire Vaudreuil, Eric Boulanger, Francois Puisieux
Summary: This study showed that older patients with ADOD were more likely to be institutionalized when the caregiver was not a direct descendant, such as a grandchild, sibling, or niece/nephew, compared to when the caregiver was the spouse.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Review
Medical Laboratory Technology
Sarahi Jaramillo Ortiz, Michael Howsam, Elisabeth H. van Aken, Joris R. Delanghe, Eric Boulanger, Frederic J. Tessier
Summary: Nails have been widely studied as a source of biomarkers for diseases, offering the potential to study biological processes over a longer time scale. They are easy to collect and store, containing information on circulating molecules and elements that reflect the subject's metabolic history.
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
(2022)