Article
Psychology, Multidisciplinary
Dennis Tay
Summary: This article introduces a target-to-source transformation approach that allows learners to creatively transform unfamiliar concepts into new target domains. The pilot implementation in a statistics course demonstrates that this approach promotes pedagogical consistency, fosters creativity, and provides teachers with new insights into students' understanding.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
History
Mahesh Gavaskar
Summary: Jotirao Phule aimed to connect the marginalized sudradi-atisudras of his time with a distant past, using concrete evidence from peasant oral traditions. His intention was to reshape the perception of the past and forge a new future, influenced by his experience of print literacy. Phule's relationship with the past was complex, involving both a rejection of the brahmanical past and a reclamation of the forgotten past of Bali. This article discusses the restoration of the unacknowledged past in Phule's attempt to improve the lives of sudradi-atisudras in the present.
INDIAN ECONOMIC AND SOCIAL HISTORY REVIEW
(2023)
Article
Biochemistry & Molecular Biology
Natalia Koralewska, Agnieszka Szczepanska, Kinga Ciechanowska, Marta Wojnicka, Maria Pokornowska, Marek C. Milewski, Dorota Gudanis, Daniel Baranowski, Chandran Nithin, Janusz M. Bujnicki, Zofia Gdaniec, Marek Figlerowicz, Anna Kurzynska-Kokorniak
Summary: G-quadruplexes play important roles in genome stability and cancer, and research shows that human Dicer can bind both RNA and DNA G-quadruplexes, leading to inhibition of pre-miRNA cleavage.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Physiology
Rikke Mulvad Sandvik, Anders Lindblad, Paul D. Robinson, Kim G. Nielsen, Per Gustafsson
Summary: Cystic fibrosis lung disease is characterized by increased ventilation inhomogeneity. This study evaluated previously published reference equations for SF6 multiple-breath washout (MBW) outcomes and produced device-specific equations if necessary. The study found that the historical reference equations were unsuitable for the EXHALYZER D data, and ventilation distribution efficiency (VDE) was a better index of ventilation inhomogeneity than LCI.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Neurosciences
Yasmin Allen-Davidian, Manuela Russo, Naohide Yamamoto, Jordy Kaufman, Alan J. Pegna, Patrick Johnston
Summary: The inversion of faces can lead to enhanced N170 amplitudes, not solely due to structural inversion but mainly because of violations of viewers' expectations across multiple parameters characterizing faces.
JOURNAL OF COGNITIVE NEUROSCIENCE
(2021)
Article
Computer Science, Software Engineering
Yan Zhang, Xiaodan Hu, Kiyoshi Kiyokawa, Xubo Yang
Summary: The occlusion-capable optical see-through head-mounted display (OC-OSTHMD) has been actively developed in recent years to accurately present mutual occlusion between virtual objects and the physical world in augmented reality (AR). In this paper, a novel approach for achieving mutual occlusion for common OSTHMDs is proposed by designing a wearable device with per-pixel occlusion capability. Upgraded OSTHMD devices are demonstrated with a prototype using HoloLens 1, showcasing real-time virtual displays with mutual occlusion. A color correction algorithm is also introduced to mitigate color aberration caused by the occlusion device. Potential applications, such as texture replacement of real objects and realistic semi-transparent object display, are demonstrated, aiming to achieve universal implementation of mutual occlusion in AR.
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2023)
Article
Computer Science, Software Engineering
Yan Zhang, Xiaodan Hu, Kiyoshi Kiyokawa, Xubo Yang
Summary: In this paper, a novel approach for realizing mutual occlusion for common OSTHMDs is proposed. The OSTHMD devices are upgraded to be occlusion-capable by attaching the device before optical combiners. A wearable device with per-pixel occlusion capability is designed, and a color correction algorithm is proposed to mitigate the color aberration caused by the occlusion device. The proposed system demonstrates the potential applications of texture replacement and realistic semi-transparent object display.
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2023)
Article
Humanities, Multidisciplinary
Petar Marceta, Wike Been, Maarten Keune
Summary: This article investigates the values of work in the creative industries in the Netherlands, exploring whether non-material values are more important than material values and how this is influenced by precarity. Two approaches, post-materialist theory and critical research on the creative industries, are evaluated. The results of the vignette survey show that the relationship between precarity and non-material work values is not straightforward. Creative workers have a clear preference for non-material values such as autonomy and self-expression, even when considering their level of precarity. These findings suggest that post-materialist theories fail to explain the values of work in the vanguard sector of post-fordist economies, highlighting the need for further research on the relationship between non-material values and precarity.
Article
Genetics & Heredity
Min-Sun Song, Jessica Alluin, John J. Rossi
Summary: Dicer-substrate small interfering RNAs (DsiRNAs) are artificial molecules with increased effectiveness compared to traditional 21-mer siRNAs, due to their novel asymmetric design. Four-looped DsiRNAs demonstrated higher gene silencing efficacy in cell experiments, highlighting the importance of Dicer in RNA interference pathways.
Editorial Material
Multidisciplinary Sciences
Istvan Taisz, Gregory S. X. E. Jefferis
Summary: The neurotransmitter dopamine has been found to play a role as a learning signal in the fly's navigation center. The fly's learning rate is influenced by its turning behavior, and only useful visual information is utilized to update its mental map.
Article
Area Studies
Kevin Gray
Summary: This paper discusses the nature of North Korea's state ideology, whether it is a variant of Soviet Marxism-Leninism or a unique indigenous ideology. The paper argues that North Korea's geopolitical insecurity and its forced march from backwardness to modernization have had a decisive impact on its state ideology. The ideology, known as Juche, is a form of developmental nationalism that draws on Marxist-Leninist origins while incorporating existing common sense forms to mobilize society. The paper critically engages with the argument that Juche represents a break from the supposedly objective laws of Marxism.
CRITICAL ASIAN STUDIES
(2023)
Editorial Material
Microbiology
Rodolphe Barrangou, Luciano A. Marraffini
Summary: This article discusses the ability of CRISPR-Cas systems to integrate invasive DNA sequences and establish adaptive immunity in bacteria. The study by Dimitriu et al. demonstrates that bacteriostatic antibiotics can induce CRISPR acquisition events, highlighting the impact of environmental conditions on the complex dynamics between host and virus, as well as the corresponding biological and genetic arms race.
CELL HOST & MICROBE
(2022)
Review
Biochemistry & Molecular Biology
Serena Silvestro, Andrea Valeri, Emanuela Mazzon
Summary: Alzheimer's disease is a neurodegenerative disorder with beta-amyloid plaques and neurofibrillary tangles of Tau proteins as its main pathological mechanisms. Aducanumab, a monoclonal antibody targeting A beta, has shown promising results in reducing Aβ accumulation and slowing cognitive impairment progression, potentially marking a milestone in the development of efficient drugs for AD.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Takao Koiso, Masayuki Goto, Toshitsugu Terakado, Yoji Komatsu, Yuji Matsumaru, Eichi Ishikawa
Summary: This study found that patients with tICH who were receiving antithrombotic treatment had lower mRS scores at discharge compared to those who were not, but had higher mortality rates within 30 days. Higher age, female gender, pre-injury VKA use, and hematoma enlargement were associated with unfavorable outcomes.
SCIENTIFIC REPORTS
(2021)
Review
Psychology, Multidisciplinary
Nathan C. Higgins, Daniel A. Pupo, Erol J. Ozmeral, David A. Eddins
Summary: The position of the head plays a crucial role in shaping the auditory information received by a listener. Technological advances have allowed for the development of assistive listening devices that can interpret movement patterns to aid in communication. Prosthetic hearing devices may also improve mobility and balance for individuals with hearing deficits. Understanding the relationship between head movement and hearing health can lead to improved signal processing strategies for assistive and augmented hearing devices.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Caroline Thivierge, Hsin-Wei Tseng, Vinay K. Mayya, Carine Lussier, Simon-Pierre Gravel, Thomas F. Duchaine
NUCLEIC ACIDS RESEARCH
(2018)
Article
Cell Biology
Thomas F. Duchaine, Marc R. Fabian
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
(2019)
Article
Biology
Seyed Mehdi Jafarnejad, Clement Chapat, Edna Matta-Camacho, Idit Anna Gelbart, Geoffrey G. Hesketh, Meztli Arguello, Aitor Garzia, Sung-Hoon Kim, Jan Attig, Maayan Shapiro, Masahiro Morita, Arkady Khoutorsky, Tommy Alain, G. Gkogkas Christos, Noam Stern-Ginossar, Thomas Tuschl, Anne-Claude Gingras, Thomas F. Duchaine, Nahum Sonenberg
Review
Genetics & Heredity
Vinay K. Mayya, Thomas F. Duchaine
FRONTIERS IN GENETICS
(2019)
Article
Biochemistry & Molecular Biology
Anh T. Tran, Eric M. Chapman, Mathieu N. Flamand, Bin Yu, Samuel J. Krempel, Thomas F. Duchaine, Matthew Eroglu, W. Brent Derry
CELL DEATH AND DIFFERENTIATION
(2019)
Article
Biochemistry & Molecular Biology
Ariel O. Donayo, Radia M. Johnson, Hsin-Wei Tseng, Said Izreig, Alexandra Gariepy, Vinay K. Mayya, Edlyn Wu, Roshni Alam, Carine Lussier, Russell G. Jones, Thomas F. Duchaine
Article
Biochemistry & Molecular Biology
Ahilya N. Sawh, Maxwell E. R. Shafer, Jun-Han Su, Xiaowei Zhuang, Siyuan Wang, Susan E. Mango
Article
Biochemistry & Molecular Biology
Alexandra Lewis, Ahmet C. Berkyurek, Andre Greiner, Ahilya N. Sawh, Ajay Vashisht, Stephanie Merrett, Mathieu N. Flamand, James Wohlschlegel, Mihail Sarov, Eric A. Miska, Thomas F. Duchaine
Article
Cell & Tissue Engineering
Jessica K. Cinkornpumin, Sin Young Kwon, Yixin Guo, Ishtiaque Hossain, Jacinthe Sirois, Colleen S. Russett, Hsin-Wei Tseng, Hiroaki Okae, Takahiro Arima, Thomas F. Duchaine, Wanlu Liu, William A. Pastor
Article
Biochemistry & Molecular Biology
Vinay K. Mayya, Mathieu N. Flamand, Alice M. Lambert, Seyed Mehdi Jafarnejad, James A. Wohlschlegel, Nahum Sonenberg, Thomas F. Duchaine
Summary: The study reveals GYF-1 and its direct interaction with IFE-4 as key miRNA effector proteins in C. elegans, leading to translation repression. Additionally, loss of gyf-1 was found to be synthetic lethal with hypomorphic alleles of certain miRNAs.
NUCLEIC ACIDS RESEARCH
(2021)
Article
Cell Biology
Ahilya N. Sawh, Susan E. Mango
Summary: Eukaryotic genome organization is ordered and can be remodeled during development. Animal model studies with high spatiotemporal resolution are necessary to understand the various forms and functions of genome organization in vivo. Recent findings in C. elegans include unexpected physiological roles for topologically associating domains, different roles for the nuclear lamina at different chromatin scales, cell-type-specific enhancer and promoter regulatory patterns, and prevalent compartment variability in early development.
CURRENT OPINION IN GENETICS & DEVELOPMENT
(2022)
Article
Biochemistry & Molecular Biology
Hsin-Wei Tseng, Anthony Mota-Sydor, Rania Leventis, Predrag Jovanovic, Ivan Topisirovic, Thomas F. Duchaine
Summary: This study reveals the direct regulation of Pten alternative polyadenylation (APA) by the mammalian cleavage factor I (CFIm) complex, impacting PTEN protein dosage and having widespread effects on APA in transcriptomes. Differential regulation of Pten APA by CFIm59 and CFIm68 is uncovered, with their divergent functions having broad impact on APA in transcriptomes.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Biochemical Research Methods
Ahilya N. Sawh, Susan E. Mango
Article
Cell Biology
Said Izreig, Alexandra Gariepy, Irem Kaymak, Hannah R. Bridges, Ariel O. Donayo, Gaelle Bridon, Lisa M. DeCamp, Susan M. Kitchen-Goosen, Daina Avizonis, Ryan D. Sheldon, Rob C. Laister, Mark D. Minden, Nathalie A. Johnson, Thomas F. Duchaine, Marc S. Rudoltz, Sanghee Yoo, Michael N. Pollak, Kelsey S. Williams, Russell G. Jones
CELL REPORTS MEDICINE
(2020)