期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 18, 期 8, 页码 861-863出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.2118
关键词
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Mechanistic details about complexin's contradictory double life as both a facilitator and an inhibitor of SNARE-mediated synaptic vesicle fusion have been challenging to uncover. A series of studies in this issue addresses the problem by revealing a switchable complexin conformation in which fusion arrest occurs when complexin clamps neighboring SNAREs.
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