Blockade of testicular and adrenal androgens in prostate cancer treatment

Androgen-Deprivation Therapy in Prostate Cancer and Cardiovascular Risk

(2010) Glenn N. Levine et al.   CIRCULATION

3β-Hydroxysteroid Dehydrogenase Is a Possible Pharmacological Target in the Treatment of Castration-Resistant Prostate Cancer

(2010) Kristen Evaul et al.   ENDOCRINOLOGY

Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate

(2010) Alison H.M. Reid et al.   JOURNAL OF CLINICAL ONCOLOGY

Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study

(2010) Howard I Scher et al.   LANCET

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of testosterone and dihydrotestosterone from dehydroepiandrosterone

(2009) Atsushi Mizokami et al.   ENDOCRINE-RELATED CANCER

Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer

(2009) Gerhardt Attard et al.   JOURNAL OF CLINICAL ONCOLOGY

Measuring therapeutic efficacy in the changing paradigm of castrate-resistant prostate cancer

(2009) P F Mulders et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

(2009) C. Tran et al.   SCIENCE

Castration-resistant prostate cancer: Targeting androgen metabolic pathways in recurrent disease

(2009) Elahe A. Mostaghel et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion

(2009) William P Harris et al.   Nature clinical practice. Urology

Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate

(2008) Olivier Barbier et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Preface

(2008) Fernand Labrie   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Mechanisms of prostate cancer progression to androgen independence

(2008) Michael J. McPhaul   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Current status and prospects of androgen depletion therapy for prostate cancer

(2008) Hideyuki Akaza   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Primary combined androgen blockade in localized disease and its mechanism

(2008) Mikio Namiki et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Expression of steroidogenic enzymes and sex-steroid receptors in human prostate

(2008) Georges Pelletier   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Androgen biosynthetic pathways in the human prostate

(2008) Van Luu-The et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

(2008) Gerhardt Attard et al.   JOURNAL OF CLINICAL ONCOLOGY

Comparable amounts of sex steroids are made outside the gonads in men and women: Strong lesson for hormone therapy of prostate and breast cancer

(2008) Fernand Labrie et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Testosterone Recovery After Prolonged Androgen Suppression in Patients With Prostate Cancer

(2008) Frederick H. Yoon et al.   JOURNAL OF UROLOGY