Integrating the active process of hair cells with cochlear function

Transduction without Tip Links in Cochlear Hair Cells Is Mediated by Ion Channels with Permeation Properties Distinct from Those of the Mechano-Electrical Transducer Channel

(2014) W. Marcotti et al.   JOURNAL OF NEUROSCIENCE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

MscS-like Mechanosensitive Channels in Plants and Microbes

(2013) Margaret E. Wilson et al.   BIOCHEMISTRY

Mechano-Gated Ion Channels in Sensory Systems

(2013) Patrick Delmas et al.   CELL

The role of transmembrane channel–like proteins in the operation of hair cell mechanotransducer channels

(2013) Kyunghee X. Kim et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular architecture of the chick vestibular hair bundle

(2013) Jung-Bum Shin et al.   NATURE NEUROSCIENCE

A Prestin Motor in Chicken Auditory Hair Cells: Active Force Generation in a Nonmammalian Species

(2013) Maryline Beurg et al.   NEURON

Adaptation of Mammalian Auditory Hair Cell Mechanotransduction Is Independent of Calcium Entry

(2013) Anthony W. Peng et al.   NEURON

TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear

(2013) Bifeng Pan et al.   NEURON

Effects of cochlear loading on the motility of active outer hair cells

(2013) D. O Maoileidigh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Remodeling of Tip Links Underlies Mechanosensory Regeneration in Auditory Hair Cells

(2013) Artur A. Indzhykulian et al.   PLOS BIOLOGY

Dynamics of Freely Oscillating and Coupled Hair Cell Bundles under Mechanical Deflection

(2012) Lea Fredrickson-Hemsing et al.   BIOPHYSICAL JOURNAL

Stereocilia Membrane Deformation: Implications for the Gating Spring and Mechanotransduction Channel

(2012) Richard J. Powers et al.   BIOPHYSICAL JOURNAL

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Kinocilia Mediate Mechanosensitivity in Developing Zebrafish Hair Cells

(2012) Katie S. Kindt et al.   DEVELOPMENTAL CELL

Molecular force transduction by ion channels – diversity and unifying principles

(2012) Sergei Sukharev et al.   JOURNAL OF CELL SCIENCE

Developmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel–like proteins

(2012) Kyunghee X. Kim et al.   JOURNAL OF GENERAL PHYSIOLOGY

Faster than the Speed of Hearing: Nanomechanical Force Probes Enable the Electromechanical Observation of Cochlear Hair Cells

(2012) Joseph C. Doll et al.   NANO LETTERS

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction

(2012) Marcos Sotomayor et al.   NATURE

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

The Spatial Pattern of Cochlear Amplification

(2012) Jonathan A.N. Fisher et al.   NEURON

Mode-locking dynamics of hair cells of the inner ear

(2012) Lea Fredrickson-Hemsing et al.   PHYSICAL REVIEW E

Coupling and Elastic Loading Affect the Active Response by the Inner Ear Hair Cell Bundles

(2012) Clark Elliott Strimbu et al.   PLoS One

Discrimination of Low-Frequency Tones Employs Temporal Fine Structure

(2012) Tobias Reichenbach et al.   PLoS One

Contribution of active hair-bundle motility to nonlinear amplification in the mammalian cochlea

(2012) F. Nin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anomalous Brownian motion discloses viscoelasticity in the ear's mechanoelectrical-transduction apparatus

(2012) A. S. Kozlov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The diverse effects of mechanical loading on active hair bundles

(2012) D. O Maoileidigh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phantom tones and suppressive masking by active nonlinear oscillation of the hair-cell bundle

(2012) J. Barral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How the Genetics of Deafness Illuminates Auditory Physiology

(2011) Guy P. Richardson et al.   Annual Review of Physiology

Coupling Active Hair Bundle Mechanics, Fast Adaptation, and Somatic Motility in a Cochlear Model

(2011) Julien Meaud et al.   BIOPHYSICAL JOURNAL

Multiple-Timescale Dynamics Underlying Spontaneous Oscillations of Saccular Hair Bundles

(2011) Yuttana Roongthumskul et al.   BIOPHYSICAL JOURNAL

Bacterial Mechanosensitive Channels as a Paradigm for Mechanosensory Transduction

(2011) Boris Martinac   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

Prestin in HEK cells is an obligate tetramer

(2011) Richard Hallworth et al.   JOURNAL OF NEUROPHYSIOLOGY

Relative stereociliary motion in a hair bundle opposes amplification at distortion frequencies

(2011) Andrei S. Kozlov et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prestin-Driven Cochlear Amplification Is Not Limited by the Outer Hair Cell Membrane Time Constant

(2011) Stuart L. Johnson et al.   NEURON

Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

(2011) Kumar N. Alagramam et al.   PLoS One

Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction

(2011) M. Grati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eukaryotic Mechanosensitive Channels

(2010) Jóhanna Árnadóttir et al.   Annual Review of Biophysics

Topology of Transmembrane Channel-like Gene 1 Protein

(2010) Valentina Labay et al.   BIOCHEMISTRY

Prestin forms oligomer with four mechanically independent subunits

(2010) Xiang Wang et al.   BRAIN RESEARCH

Somatic motility and hair bundle mechanics, are both necessary for cochlear amplification?

(2010) Anthony W. Peng et al.   HEARING RESEARCH

A Critique of the Critical Cochlea: Hopf—a Bifurcation—Is Better Than None

(2010) A. J. Hudspeth et al.   JOURNAL OF NEUROPHYSIOLOGY

The interplay between active hair bundle motility and electromotility in the cochlea

(2010) Dáibhid Ó Maoiléidigh et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset

(2010) Nicolas X Tritsch et al.   NATURE NEUROSCIENCE

Structural Determinants of Cadherin-23 Function in Hearing and Deafness

(2010) Marcos Sotomayor et al.   NEURON

Dual Contribution to Amplification in the Mammalian Inner Ear

(2010) Tobias Reichenbach et al.   PHYSICAL REVIEW LETTERS

Interactions between Hair Cells Shape Spontaneous Otoacoustic Emissions in a Model of the Tokay Gecko's Cochlea

(2010) Michael Gelfand et al.   PLoS One

Coupling a sensory hair-cell bundle to cyber clones enhances nonlinear amplification

(2010) J. Barral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Mechanotransduction by Hair Cells: Models, Molecules, and Mechanisms

(2009) Peter G. Gillespie et al.   CELL

Spikes and Membrane Potential Oscillations in Hair Cells Generate Periodic Afferent Activity in the Frog Sacculus

(2009) M. A. Rutherford et al.   JOURNAL OF NEUROSCIENCE

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging

(2009) Maryline Beurg et al.   NATURE NEUROSCIENCE

The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafish

(2009) Michelle R. Gleason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency Clustering in Spontaneous Otoacoustic Emissions from a Lizard's Ear

(2008) Andrej Vilfan et al.   BIOPHYSICAL JOURNAL

Cochlear amplification, outer hair cells and prestin

(2008) Peter Dallos   CURRENT OPINION IN NEUROBIOLOGY

Three-dimensional Architecture of Hair-bundle Linkages Revealed by Electron-microscopic Tomography

(2008) Manfred Auer et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Neurosensory mechanotransduction

(2008) Martin Chalfie   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Making an Effort to Listen: Mechanical Amplification in the Ear

(2008) A.J. Hudspeth   NEURON

Prestin-Based Outer Hair Cell Motility Is Necessary for Mammalian Cochlear Amplification

(2008) Peter Dallos et al.   NEURON

Cochlear Outer Hair Cell Motility

(2008) Jonathan Ashmore   PHYSIOLOGICAL REVIEWS

Enhancement of sensitivity gain and frequency tuning by coupling of active hair bundles

(2008) K. Dierkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA