Obesity and the brain: how convincing is the addiction model?

An fMRI study of obesity, food reward, and perceived caloric density. Does a low-fat label make food less appealing?

(2011) Janet Ng et al.   APPETITE

Evidence that ‘food addiction’ is a valid phenotype of obesity

(2011) Caroline Davis et al.   APPETITE

Can food be addictive? Public health and policy implications

(2011) Ashley N. Gearhardt et al.   ADDICTION

Addiction Circuitry in the Human Brain

(2011) Nora D. Volkow et al.   Annual Review of Pharmacology and Toxicology

Neural Correlates of Food Addiction

(2011) Ashley N. Gearhardt   ARCHIVES OF GENERAL PSYCHIATRY

Altered Temporal Difference Learning in Bulimia Nervosa

(2011) Guido K.W. Frank et al.   BIOLOGICAL PSYCHIATRY

Opiates, overeating and obesity: a psychogenetic analysis

(2011) C Davis et al.   INTERNATIONAL JOURNAL OF OBESITY

The global obesity pandemic: shaped by global drivers and local environments

(2011) Boyd A Swinburn et al.   LANCET

Quantification of the effect of energy imbalance on bodyweight

(2011) Kevin D Hall et al.   LANCET

Common cellular and molecular mechanisms in obesity and drug addiction

(2011) Paul J. Kenny   NATURE REVIEWS NEUROSCIENCE

Enhanced Striatal Dopamine Release During Food Stimulation in Binge Eating Disorder

(2011) Gene-Jack Wang et al.   Obesity

Attentional Bias to Food Images Associated With Elevated Weight and Future Weight Gain: An fMRI Study

(2011) Sonja Yokum et al.   Obesity

Rats that binge eat fat-rich food do not show somatic signs or anxiety associated with opiate-like withdrawal: Implications for nutrient-specific food addiction behaviors

(2011) Miriam E. Bocarsly et al.   PHYSIOLOGY & BEHAVIOR

Differential Neural Responses to Food Images in Women with Bulimia versus Anorexia Nervosa

(2011) Samantha J. Brooks et al.   PLoS One

Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

(2011) Trevor W. Robbins et al.   TRENDS IN COGNITIVE SCIENCES

The Emerging Link Between Alcoholism Risk and Obesity in the United States

(2010) Richard A. Grucza et al.   ARCHIVES OF GENERAL PSYCHIATRY

Decreased dopamine type 2 receptor availability after bariatric surgery: Preliminary findings

(2010) Julia P. Dunn et al.   BRAIN RESEARCH

Reward abnormalities among women with full and subthreshold bulimia nervosa: A functional magnetic resonance imaging study

(2010) Cara Bohon et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Obese children show hyperactivation to food pictures in brain networks linked to motivation, reward and cognitive control

(2010) A S Bruce et al.   INTERNATIONAL JOURNAL OF OBESITY

Genetically Determined Differences in Brain Response to a Primary Food Reward

(2010) J. A. Felsted et al.   JOURNAL OF NEUROSCIENCE

Weight Gain Is Associated with Reduced Striatal Response to Palatable Food

(2010) E. Stice et al.   JOURNAL OF NEUROSCIENCE

A genetic determinant of the striatal dopamine response to alcohol in men

(2010) V A Ramchandani et al.   MOLECULAR PSYCHIATRY

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

(2010) Paul M Johnson et al.   NATURE NEUROSCIENCE

Reward circuitry responsivity to food predicts future increases in body mass: Moderating effects of DRD2 and DRD4

(2010) Eric Stice et al.   NEUROIMAGE

Body mass correlates inversely with inhibitory control in response to food among adolescent girls: An fMRI study

(2010) Laura Batterink et al.   NEUROIMAGE

Reduced accumbens dopamine in Sprague–Dawley rats prone to overeating a fat-rich diet

(2010) Pedro Rada et al.   PHYSIOLOGY & BEHAVIOR

Association study between the DAT1, DBH and DRD2 genes and cocaine dependence in a Spanish sample

(2010) Noèlia Fernàndez-Castillo et al.   PSYCHIATRIC GENETICS

Reward, dopamine and the control of food intake: implications for obesity

(2010) Nora D. Volkow et al.   TRENDS IN COGNITIVE SCIENCES

Compulsive overeating as an addiction disorder. A review of theory and evidence

(2009) Caroline Davis et al.   APPETITE

Initial Evidence of an Association Between OPRM1 and Adolescent Alcohol Misuse

(2009) Robert Miranda et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The plausibility of sugar addiction and its role in obesity and eating disorders

(2009) David Benton   CLINICAL NUTRITION

Increased dorsolateral prefrontal cortex activation in obese children during observation of food stimuli

(2009) S Davids et al.   INTERNATIONAL JOURNAL OF OBESITY

Food Addiction

(2009) Ashley N. Gearhardt et al.   Journal of Addiction Medicine

Personality Predicts the Brain's Response to Viewing Appetizing Foods: The Neural Basis of a Risk Factor for Overeating

(2009) L. Passamonti et al.   JOURNAL OF NEUROSCIENCE

Sugar and Fat Bingeing Have Notable Differences in Addictive-like Behavior

(2009) Nicole M. Avena et al.   JOURNAL OF NUTRITION

Symposium Overview—Food Addiction: Fact or Fiction?

(2009) Rebecca L. Corwin et al.   JOURNAL OF NUTRITION

Refined food addiction: A classic substance use disorder

(2009) J.R. Ifland et al.   MEDICAL HYPOTHESES

The Salted Food Addiction Hypothesis may explain overeating and the obesity epidemic

(2009) James A. Cocores et al.   MEDICAL HYPOTHESES

Human genetics illuminates the paths to metabolic disease

(2009) Stephen O’Rahilly   NATURE

Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity

(2009) B.M. Geiger et al.   NEUROSCIENCE

DRD2 -related TaqIA polymorphism modulates motivation to smoke

(2009) Yantao Zuo et al.   NICOTINE & TOBACCO RESEARCH

Association of the DRD2 gene Taq1A polymorphism and smoking behavior: A meta-analysis and new data

(2009) Marcus R. Munafò et al.   NICOTINE & TOBACCO RESEARCH

Obesity, diets, and social inequalities

(2009) Adam Drewnowski   NUTRITION REVIEWS

Neural Mechanisms Associated With Food Motivation in Obese and Healthy Weight Adults

(2009) Laura E. Martin et al.   Obesity

Alterations of Central Dopamine Receptors Before and After Gastric Bypass Surgery

(2009) Kimberley E. Steele et al.   OBESITY SURGERY

Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution

(2009) Alexandra Doehring et al.   Pharmacogenetics and Genomics

Preliminary validation of the Yale Food Addiction Scale

(2008) Ashley N. Gearhardt et al.   APPETITE

Binge-Eating Disorder: Reward Sensitivity and Brain Activation to Images of Food

(2008) Anne Schienle et al.   BIOLOGICAL PSYCHIATRY

Evidence for defective mesolimbic dopamine exocytosis in obesity-prone rats

(2008) Brenda M. Geiger et al.   FASEB JOURNAL

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors

(2008) Nora D. Volkow et al.   NEUROIMAGE

Impulsivity as a vulnerability marker for substance-use disorders: Review of findings from high-risk research, problem gamblers and genetic association studies

(2008) Antonio Verdejo-García et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction

(2008) B. J Everitt et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Neurobiological mechanisms for opponent motivational processes in addiction

(2008) G. F Koob et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Relation Between Obesity and Blunted Striatal Response to Food Is Moderated by TaqIA A1 Allele

(2008) E. Stice et al.   SCIENCE

Sensitivity to reward and body mass index (BMI): Evidence for a non-linear relationship

(2007) Caroline Davis et al.   APPETITE

A family history study of binge-eating disorder

(2007) Lisa R.R. Lilenfeld et al.   COMPREHENSIVE PSYCHIATRY

Personality and eating behaviors: A case–control study of binge eating disorder

(2007) Caroline Davis et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake

(2007) Nicole M. Avena et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS