☆ 4.6 Editorial Material

ALZHEIMER DISEASE New light on an old CLU

NATURE REVIEWS NEUROLOGY (2010)

期刊

NATURE REVIEWS NEUROLOGY

卷 6, 期 1, 页码 11-13

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NATURE PUBLISHING GROUP

DOI: 10.1038/nrneurol.2009.213

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Clinical Neurology

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NIMH NIH HHS [R37 MH060009, R37 MH060009-10] Funding Source: Medline
NATIONAL INSTITUTE OF MENTAL HEALTH [R37MH060009] Funding Source: NIH RePORTER

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摘要

Genome-wide association studies (gwas) have uncovered over two dozen candidate Alzheimer disease susceptibility genes; however, the results of these studies showed limited overlap. Two independently performed gwas involving cohorts from Europe and the us have now identified three additional putative Alzheimer disease genes that show modest but remarkably consistent effects across data sets.

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