Article
Medicine, General & Internal
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Kook-Hwan Oh, Joongyub Lee, Yun Kyu Oh, Ji Yong Jung, Kyu Hun Choi, Seong Kwon Ma, Eun Hui Bae, Soo Wan Kim
Summary: This study found an association between circulating OPG levels and long-term visit-to-visit blood pressure variability in patients with pre-dialysis CKD.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Elaine Ku, Charles E. E. McCulloch, Lesley A. A. Inker, Hocine Tighiouart, Franz Schaefer, Elke Wuehl, Piero Ruggenenti, Giuseppe Remuzzi, Barbara A. A. Grimes, Mark J. J. Sarnak
Summary: This pooled analysis of seven trials shows that intensive blood pressure control can delay the onset of kidney replacement therapy in patients with CKD stages 4-5, but does not necessarily have an effect in CKD stage 3 patients. Therefore, future trials focusing on blood pressure targets in populations with advanced kidney disease are needed.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Biochemistry & Molecular Biology
Fengyao Yan, Dan-Qian Chen, Jijun Tang, Ying-Yong Zhao, Yan Guo
Summary: Controlling blood pressure is crucial for curbing kidney function decline and reducing the risk of cardiovascular disease in chronic kidney disease (CKD) patients. Ten metabolites that have significant associations with blood pressure were identified, and their quantitative importance was verified.
Review
Medicine, General & Internal
Sidar Copur, Metehan Berkkan, Pantelis Sarafidis, Mehmet Kanbay
Summary: Chronic kidney disease (CKD) and dementia are common comorbidities, especially in the elderly population, but there is no consensus on the increased risk of dementia in CKD patients. Recent studies have investigated the potential therapeutic role of intensive blood pressure control, but there are limitations and a lack of specific management guidelines. This review examines the impact of blood pressure and other factors on dementia risk in CKD patients, along with potential pathophysiological mechanisms and future guidance.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Review
Urology & Nephrology
Carmine Zoccali, Francesca Mallamaci, Eugenio Picano
Summary: Fluid overload is common in patients with chronic kidney disease, especially those with kidney failure. Lung ultrasound can accurately estimate lung water in these patients. Studies have shown a high prevalence of asymptomatic lung congestion in patients with kidney failure, which is only weakly associated with fluid excess. Lung congestion is dose-dependently correlated with death risk. Treatment guided by lung ultrasound can relieve lung congestion, but may not significantly reduce the risk of combined endpoints. However, post hoc analysis has shown that lung ultrasound can reduce the risk of recurrent acute heart failure and cardiovascular events. Therefore, lung ultrasound has important clinical implications for patients with chronic kidney disease.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Peripheral Vascular Disease
Anika T. Singh, Sushrut S. Waikar, Finnian R. Mc Causland
Summary: Intradialytic hypertension in hemodialysis patients is associated with increased mortality risk, but there is no consensus on its definition. This study found that any increase in systolic blood pressure from prehemodialysis to posthemodialysis was associated with the highest adjusted risk of mortality, compared to other threshold-based definitions.
Article
Nutrition & Dietetics
Sharon Turban, Stephen P. Juraschek, Edgar R. Miller, Cheryl A. M. Anderson, Karen White, Jeanne Charleston, Lawrence J. Appel
Summary: In individuals with chronic kidney disease, increasing dietary potassium intake did not significantly lower blood pressure. However, there was a potential risk of hyperkalemia associated with a higher potassium diet, indicating the need for caution when adjusting dietary potassium intake in this population.
Article
Transplantation
Roberto Minutolo, Francis B. Gabbai, Rajiv Agarwal, Carlo Garofalo, Silvio Borrelli, Paolo Chiodini, Simona Signoriello, Ernesto Paoletti, Maura Ravera, Vincenzo Bellizzi, Giuseppe Conte, Luca De Nicola
Summary: The study revealed that higher ambulatory blood pressure (ABP) levels significantly increase the risks of end-stage kidney disease (ESKD) and mortality in men with chronic kidney disease (CKD). However, maintaining blood pressure at target levels can reduce the risks of ESKD and death in male patients.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Medicine, General & Internal
Chun Yin See, Chien-Tzu Tseng, Wei-Ren Lin, Jo-Yen Chao, Te-Hui Kuo, Ming-Cheng Wang
Summary: This study found that seasonal blood pressure changes were associated with outcomes in patients with chronic kidney disease in southern Taiwan. Patients with elevated blood pressure in wintertime were older and had a higher prevalence of diabetic nephropathy, leading to worse outcomes. Home blood pressure monitoring was shown to be crucial for better outcomes in these patients.
FRONTIERS IN MEDICINE
(2021)
Letter
Peripheral Vascular Disease
Rafael Lopez, Timothy Copeland, Charles McCulloch, Elaine Ku
Summary: This study analyzes data from the AASK Trial and finds that there is an additive and synergistic effect between RAAS inhibition and intensive blood pressure lowering in reducing proteinuria.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Peripheral Vascular Disease
Avishai M. Tsur, Inbal Akavian, Estela Derazne, Dorit Tzur, Asaf Vivante, Ehud Grossman, Ran S. Rotem, Boris Fishman, Arnon Afek, Josef Coresh, Gabriel Chodick, Gilad Twig
Summary: The study found an association between blood pressure above 130/80 mm Hg in adolescence and the risk of early kidney damage in young adulthood, especially for overweight and obese adolescents.
Article
Peripheral Vascular Disease
Masako Kochi, Kentaro Kohagura, Nanako Oshiro, Ryo Zamami, Kazufumi Nagahama, Koshi Nakamura, Yusuke Ohya
Summary: This study investigates the impact of hyperuricemia (HU) on the association between systolic blood pressure (SBP) and the prevalence of proteinuria and low estimated glomerular filtration rate (eGFR) in the general population. The findings show that HU increases the risk of proteinuria. This trend is more pronounced in participants with HU, and there is an interactive effect of SBP and HU on the prevalence of proteinuria. Additionally, the risk of low eGFR increases with elevated SBP in individuals with proteinuria, but decreases in those without proteinuria. These trends are more prevalent in participants with HU.
HYPERTENSION RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Hyeok-Hee Lee, Hokyou Lee, Raymond R. Townsend, Dong-Wook Kim, Sungha Park, Hyeon Chang Kim
Summary: The study found that adhering to the blood pressure target adjusted by the 2021 KDIGO guideline significantly reduces cardiovascular disease risk among non-dialysis CKD patients; for individual patients, there is a higher risk for those who only adhere to the 2012 KDIGO or 2017 ACC/AHA guidelines.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Peripheral Vascular Disease
Jun Zhang, Jun Song, Liping Zhou, Wenying Zhou, Jialing Rao, Yuanqing Li, Jianhao Wu, Hui Peng, Tanqi Lou
Summary: Nocturnal systolic blood pressure (SBP) is independently associated with target organ damage (TOD) in chronic kidney disease (CKD) patients with normotension, while nocturnal diastolic blood pressure (DBP) is not correlated with proteinuria. Targeting a nocturnal SBP to less than 114 mmHg or even less than 104 mmHg may help prevent TOD in patients with CKD.
JOURNAL OF HYPERTENSION
(2021)
Article
Peripheral Vascular Disease
Maria Korogiannou, Pantelis Sarafidis, Marieta P. Theodorakopoulou, Maria Eleni Alexandrou, Efstathios Xagas, Antonis Argyris, Athanase Protogerou, Charles J. Ferro, Ioannis N. Boletis, Smaragdi Marinaki
Summary: Blood pressure control in male and female kidney transplant recipients is similar according to office criteria, but significantly different according to ambulatory blood pressure monitoring criteria. Worse ambulatory blood pressure control in males may interfere with renal and cardiovascular outcomes.
JOURNAL OF HYPERTENSION
(2022)
