Epistasis and quantitative traits: using model organisms to study gene–gene interactions

Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice

(2012) Sabrina H Spiezio et al.   BMC GENETICS

More Than the Sum of Its Parts: A Complex Epistatic Network Underlies Natural Variation in Thermal Preference Behavior in Caenorhabditis elegans

(2012) Bryn E. Gaertner et al.   GENETICS

Extensive epistasis for olfactory behaviour, sleep and waking activity in Drosophila melanogaster

(2012) SHILPA SWARUP et al.   Genetics Research

New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis

(2012) Sibylle Sabrautzki et al.   MAMMALIAN GENOME

The Drosophila melanogaster Genetic Reference Panel

(2012) Trudy F. C. Mackay et al.   NATURE

Epistasis dominates the genetic architecture of Drosophila quantitative traits

(2012) W. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The future of livestock breeding: genomic selection for efficiency, reduced emissions intensity, and adaptation

(2012) Ben J. Hayes et al.   TRENDS IN GENETICS

Genomic value prediction for quantitative traits under the epistatic model

(2011) Zhiqiu Hu et al.   BMC GENETICS

Marker-assisted prediction of non-additive genetic values

(2011) Nanye Long et al.   GENETICA

TheDrosophilaGene Disruption Project: Progress Using Transposons With Distinctive Site Specificities

(2011) Hugo J. Bellen et al.   GENETICS

Mapping genetic loci that interact with myostatin to affect growth traits

(2011) Y Cheng et al.   HEREDITY

An integrated approach to characterize genetic interaction networks in yeast metabolism

(2011) Balázs Szappanos et al.   NATURE GENETICS

Mapping of signaling networks through synthetic genetic interaction analysis by RNAi

(2011) Thomas Horn et al.   NATURE METHODS

Complex genetic architecture of Drosophila aggressive behavior

(2011) L. Zwarts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of mutant-assisted gene identification and characterization (MAGIC) to identify novel genetic loci that modify the maize hypersensitive response

(2011) Vijay Chaikam et al.   THEORETICAL AND APPLIED GENETICS

Beyond Missing Heritability: Prediction of Complex Traits

(2011) Robert Makowsky et al.   PLoS Genetics

Replication and Explorations of High-Order Epistasis Using a Large Advanced Intercross Line Pedigree

(2011) Mats Pettersson et al.   PLoS Genetics

Sex-, Diet-, and Cancer-Dependent Epistatic Effects on Complex Traits in Mice

(2011) Larry J. Leamy et al.   Frontiers in Genetics

Mapping the Epistatic Network Underlying Murine Reproductive Fatpad Variation

(2010) J. P. Jarvis et al.   GENETICS

Dissection of genetically complex traits with extremely large pools of yeast segregants

(2010) Ian M. Ehrenreich et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Quantitative and Molecular Genetic Analyses of Mutations Increasing Drosophila Life Span

(2010) Michael M. Magwire et al.   PLoS Genetics

Quantitative Trait Loci for Aggressive Behavior in Drosophila melanogaster

(2009) A. C. Edwards et al.   GENETICS

Epistatic interactions attenuate mutations affecting startle behaviour in Drosophila melanogaster

(2009) AKIHIKO YAMAMOTO et al.   Genetics Research

Genetic architecture of quantitative traits in mice, flies, and humans

(2009) J. Flint et al.   GENOME RESEARCH

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Systems genetics of complex traits in Drosophila melanogaster

(2009) Julien F Ayroles et al.   NATURE GENETICS

Detecting gene–gene interactions that underlie human diseases

(2009) Heather J Cordell   NATURE REVIEWS GENETICS

The genetics of quantitative traits: challenges and prospects

(2009) Trudy F. C. Mackay et al.   NATURE REVIEWS GENETICS

Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture

(2009) Casey S. Greene et al.   PLoS One

Genetic Interactions Between Transcription Factors Cause Natural Variation in Yeast

(2009) J. Gerke et al.   SCIENCE

The Genetic Architecture of Maize Flowering Time

(2009) E. S. Buckler et al.   SCIENCE

Genomic Consequences of Background Effects on scalloped Mutant Expressivity in the Wing of Drosophila melanogaster

(2008) I. Dworkin et al.   GENETICS

A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci

(2008) G D Gale et al.   MOLECULAR PSYCHIATRY

Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems

(2008) Patrick C. Phillips   NATURE REVIEWS GENETICS

Biochemical Networks and Epistasis Shape the Arabidopsis thaliana Metabolome

(2008) H. C. Rowe et al.   PLANT CELL

HSP90-buffered genetic variation is common in Arabidopsis thaliana

(2008) T. A. Sangster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis

(2008) H. Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

(2008) David L. Aylor et al.   PLoS Genetics

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics