标题
Emerging therapeutic opportunities for skeletal restoration
作者
关键词
-
出版物
NATURE REVIEWS DRUG DISCOVERY
Volume 10, Issue 2, Pages 141-156
出版商
Springer Nature
发表日期
2011-02-01
DOI
10.1038/nrd3299
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Leptin-dependent co-regulation of bone and energy metabolism
- (2016) Vijay K. Yadav et al. Aging-US
- The many facets of PPARγ: novel insights for the skeleton
- (2010) Masanobu Kawai et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Serum Osteocalcin Is Associated With Measures of Insulin Resistance, Adipokine Levels, and the Presence of Metabolic Syndrome
- (2010) Umer Saleem et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition
- (2010) Keertik Fulzele et al. CELL
- Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism
- (2010) Mathieu Ferron et al. CELL
- PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss
- (2010) Wei Wei et al. Cell Metabolism
- Minireview: A Skeleton in Serotonin’s Closet?
- (2010) Masanobu Kawai et al. ENDOCRINOLOGY
- Bisphosphonates and RANK ligand inhibitors for the treatment and prevention of metastatic bone disease
- (2010) H.L. Neville-Webbe et al. EUROPEAN JOURNAL OF CANCER
- Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels
- (2010) Bu B Yeap et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Effects of recombinant insulin-like growth factor-I and growth hormone on bone turnover in elderly women
- (2010) Laura J. Ghiron et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Biochemical markers of bone turnover
- (2010) Pierre D. Delmas JOURNAL OF BONE AND MINERAL RESEARCH
- Microarchitectural deterioration of cortical and trabecular bone: Differing effects of denosumab and alendronate
- (2010) Ego Seeman et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
- (2010) Michael S Ominsky et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin: A gem from the genome leads to bone-building antibodies
- (2010) Chris Paszty et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
- (2010) Desmond Padhi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The IGF-I regulatory system and its impact on skeletal and energy homeostasis
- (2010) Masanobu Kawai et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Parathyroid Hormone-Related Protein for the Treatment of Postmenopausal Osteoporosis: Defining the Maximal Tolerable Dose
- (2010) Mara J. Horwitz et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A Cross-Sectional Evaluation of the Effect of Risperidone and Selective Serotonin Reuptake Inhibitors on Bone Mineral Density in Boys
- (2010) Chadi A. Calarge et al. JOURNAL OF CLINICAL PSYCHIATRY
- Osteonecrosis of the Jaw in a Patient on Denosumab
- (2010) Tara L. Aghaloo et al. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
- Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study
- (2010) David Thomas et al. LANCET ONCOLOGY
- Wnt Inhibitory Factor 1 Decreases Tumorigenesis and Metastasis in Osteosarcoma
- (2010) E. M. Rubin et al. MOLECULAR CANCER THERAPEUTICS
- Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis
- (2010) Vijay K Yadav et al. NATURE MEDICINE
- Placebo-Controlled Trials in Osteoporosis — Proceeding with Caution
- (2010) Clifford J. Rosen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lasofoxifene in Postmenopausal Women with Osteoporosis
- (2010) Steven R. Cummings et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy
- (2010) U. Krause et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR- nuclear translocation
- (2010) M. Kawai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Societal Burden of Osteoporosis
- (2010) David J. Becker et al. Current Rheumatology Reports
- γ-Carboxylation of osteocalcin and insulin resistance in older men and women
- (2009) M Kyla Shea et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- The Expanded Biology of Serotonin
- (2009) Miles Berger et al. Annual Review of Medicine
- Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells
- (2009) Sun Wook Cho et al. BONE
- Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic parameters and overall safety profile
- (2009) Rogerio A. Lobo et al. FERTILITY AND STERILITY
- Efficacy of tissue-selective estrogen complex of bazedoxifene/conjugated estrogens for osteoporosis prevention in at-risk postmenopausal women
- (2009) Robert Lindsay et al. FERTILITY AND STERILITY
- Prevalence, Health Care Expenditures, and Orthopedic Surgery Workforce for Musculoskeletal Conditions
- (2009) Robert H. Haralson JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Effects of denosumab on bone mineral density and bone turnover in postmenopausal women transitioning from alendronate therapy
- (2009) David L Kendler et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice
- (2009) Maya Kansara et al. JOURNAL OF CLINICAL INVESTIGATION
- Selective Serotonin Reuptake Inhibiting Antidepressants Are Associated With an Increased Risk of Nonvertebral Fractures
- (2009) Gijsbertus Ziere et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Fracture Risk From Psychotropic Medications
- (2009) James M. Bolton et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Bisphosphonates: Mechanism of Action and Role in Clinical Practice
- (2009) Matthew T. Drake et al. MAYO CLINIC PROCEEDINGS
- TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
- (2009) Yi Tang et al. NATURE MEDICINE
- Fat targets for skeletal health
- (2009) Masanobu Kawai et al. Nature Reviews Rheumatology
- Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
- (2009) Steven R. Cummings et al. NEW ENGLAND JOURNAL OF MEDICINE
- Preference and satisfaction with a 6-month subcutaneous injection versus a weekly tablet for treatment of low bone mass
- (2009) D. L. Kendler et al. OSTEOPOROSIS INTERNATIONAL
- Of mice and men: divergent risks of teriparatide-induced osteosarcoma
- (2009) V. Subbiah et al. OSTEOPOROSIS INTERNATIONAL
- Fat and Beyond: The Diverse Biology of PPARγ
- (2008) Peter Tontonoz et al. Annual Review of Biochemistry
- Lithium's effect on bone mineral density
- (2008) Ali Zamani et al. BONE
- Selective Serotonin Reuptake Inhibitors and Other Antidepressants and Risk of Fracture
- (2008) Peter Vestergaard et al. CALCIFIED TISSUE INTERNATIONAL
- Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum
- (2008) Vijay K. Yadav et al. CELL
- Bone Remodeling, Energy Metabolism, and the Molecular Clock
- (2008) Clifford J. Rosen Cell Metabolism
- Breast cancer‐derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
- (2008) Guojun Bu et al. INTERNATIONAL JOURNAL OF CANCER
- Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial*
- (2008) Stuart L Silverman et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma
- (2008) Deborah J Heath et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Plasma Osteocalcin Is Inversely Related to Fat Mass and Plasma Glucose in Elderly Swedish Men
- (2008) Jenny M Kindblom et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Comparison of the Effect of Denosumab and Alendronate on BMD and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial*
- (2008) Jacques P Brown et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*
- (2008) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Subtrochanteric and Diaphyseal Femur Fractures in Patients Treated With Alendronate: A Register-Based National Cohort Study
- (2008) Bo Abrahamsen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity
- (2008) Eiichi Hinoi et al. JOURNAL OF CELL BIOLOGY
- What do we know about serotonin?
- (2008) Catherine Jonnakuty et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Association between Serum Osteocalcin and Markers of Metabolic Phenotype
- (2008) Anastassios G. Pittas et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Building bone to reverse osteoporosis and repair fractures
- (2008) Sundeep Khosla et al. JOURNAL OF CLINICAL INVESTIGATION
- Pharmacological targeting of the serotonergic system for the treatment of obesity
- (2008) Alastair S. Garfield et al. JOURNAL OF PHYSIOLOGY-LONDON
- Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study
- (2008) B. A. Lenart et al. OSTEOPOROSIS INTERNATIONAL
- Insulin-like growth factor-I and bone: lessons from mice and men
- (2008) Masanobu Kawai et al. PEDIATRIC NEPHROLOGY
- Antipsychotic-Induced Hyperprolactinemia
- (2008) Jolene R Bostwick et al. PHARMACOTHERAPY
- Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
- (2008) Mathieu Ferron et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate
- (2008) L. Pederson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started