Review
Immunology
Thomas Samuel Ram, Vinotha Thomas, Arvind Sathyamurthy, Jeba Karunya Ramireddy, Neenu Oliver John, Anitha Thomas, Abraham Peedicayil
Summary: The global increase in cancer burden poses a challenge for countries with scarce resources, with gynecological cancer remaining prevalent. Training gynecologic oncologists is crucial in decreasing morbidity and mortality rates, with challenges and opportunities existing in the development of training programs, particularly in developing countries like India.
INDIAN JOURNAL OF MEDICAL RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Adam M. Boyce, Denis J. Cumming, Chun Huang, Stanislaw P. Zankowski, Patrick S. Grant, Dan J. L. Brett, Paul R. Shearing
Summary: Current research is allowing for thicker lithium-ion battery electrodes, which can improve energy density and reduce costs, but challenges such as performance issues, manufacturing challenges, and scalability remain. Pore engineering may provide opportunities to design thicker and better electrodes while ensuring long-term performance and scalability.
Article
Biochemical Research Methods
Sangkyun Cho, Dennis E. Discher, Kam W. Leong, Gordana Vunjak-Novakovic, Joseph C. Wu
Summary: This Perspective discusses the technologies and challenges in cardiac tissue engineering, and proposes strategies to overcome these challenges. Engineered cardiac tissues derived from human induced pluripotent stem cells offer unique opportunities for personalized disease modeling, drug discovery, and cardiac repair. However, there are still major obstacles to be addressed before the field can move towards commercial and clinical translation.
Article
Computer Science, Hardware & Architecture
Xu Li, Paul Russell, Catalina Mladin, Chonggang Wang
Summary: This article discusses the applications of blockchain technology in wireless applications, reviewing blockchain technology and 5G system architecture, presenting the benefits of blockchain technology and proposing a wireless blockchain middleware architecture as a potential solution to address challenges. Future research directions such as inter-blockchain interactions, efficient blockchain transaction management, and blockchain-based messaging in future wireless systems like 5G, beyond 5G, and 6G are also highlighted.
IEEE WIRELESS COMMUNICATIONS
(2021)
Review
Biochemical Research Methods
Matteo Chiara, Anna Maria D'Erchia, Carmela Gissi, Caterina Manzari, Antonio Parisi, Nicoletta Resta, Federico Zambelli, Ernesto Picardi, Giulio Pavesi, David S. Horner, Graziano Pesole
Summary: Various NGS-based strategies have been used to trace infectious agent origins and develop molecular diagnostic tests. The ongoing COVID-19 pandemic has caused severe societal and economic costs, emphasizing the importance of efficient sequencing methods. However, different technologies and approaches have their own advantages and limitations, highlighting the need for better integration and sharing of data.
BRIEFINGS IN BIOINFORMATICS
(2021)
Review
Biochemical Research Methods
Shu Zhu, Yaohui Fang, Kefan Guo, Zhonghua Ni, Nan Xiang
Summary: Conventional cancer diagnosis requires invasive tissue biopsy, causing severe harm to patients. Liquid biopsy, with its minimal invasiveness, has shown potential for real-time cancer diagnosis but still cannot replace tissue biopsy in most settings. This paper discusses the challenges and limitations of existing liquid biopsy instruments, as well as the opportunities and future progression of next-generation tools. Ultimately, the goal is to integrate liquid biopsy into clinical workflows and establish it as a validated and reliable tool for cancer diagnosis.
Review
Food Science & Technology
Priyanka Suthar, Satish Kumar, Vikas Kumar, Vishal Sharma, Atul Dhiman
Summary: Consumers' interest in health promoting foods has led to the development of novel biological compounds with diverse health benefits in the food industry. Postbiotics, as potential functional food compounds, have been well-studied in terms of their interaction, production, processing, and safety. The review explores the challenges and opportunities in improving growth mediums, cell lysis, extraction, characterization, stability, and applications of postbiotics in both the food and pharma industry, along with market trends, success stories, and safety concerns. Extensive investigations and clinical documentation have validated the physiological benefits and additional bioactivity of postbiotics, emphasizing the importance of documenting their bioactivity and safety.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Necla Birgul Iyison, Aida Shahraki, Kubra Kahveci, Mustafa Barbaros Duzgun, Gokhan Gun
Summary: The urgent need for developing next-generation pesticides due to increasing human population and inefficiency of available pesticides is highlighted. Targeting invertebrate GPCRs has great potential in pesticide development, but further genomic and transcriptomic data are necessary for a full utilization of this strategy.
Review
Oncology
Anna Maria Frustaci, Marina Deodato, Giulia Zamprogna, Roberto Cairoli, Marco Montillo, Alessandra Tedeschi
Summary: The treatment scenario for chronic lymphocytic leukemia (CLL) is rapidly evolving. Ibrutinib has revolutionized CLL treatment, but long-term toxicities and resistance are concerns. Next-generation BTK inhibitors, such as acalabrutinib and zanubrutinib, have demonstrated a lower incidence of adverse events compared to ibrutinib. Reversible inhibitors have shown efficacy regardless of previous treatment and the presence of BTK mutations.
Review
Chemistry, Analytical
Erin K. Purcell, Michael F. Becker, Yue Guo, Seth A. Hara, Kip A. Ludwig, Collin J. McKinney, Elizabeth M. Monroe, Robert Rechenberg, Cory A. Rusinek, Akash Saxena, James R. Siegenthaler, Caryl E. Sortwell, Cort H. Thompson, James K. Trevathan, Suzanne Witt, Wen Li
Summary: Carbon-based electrodes, like carbon fiber microelectrodes, have a long history of use in neurochemical sensing, but are limited in fabrication, flexibility, and stability. Boron-doped diamond electrodes offer improved electrochemical properties and biocompatibility, allowing for high-throughput batch fabrication and customization of electrode arrays for neurochemical sensing applications. Opportunities exist to further enhance the performance of diamond electrodes through various methods such as anodic pretreatment and waveform optimization.
Article
Engineering, Electrical & Electronic
Bassel Al Homssi, Akram Al-Hourani, Ke Wang, Phillip Conder, Sithamparanathan Kandeepan, Jinho Choi, Ben Allen, Ben Moores
Summary: This article systematically analyzes the opportunities and challenges of next-generation LEO mega satellite constellations, providing insights for network designers while introducing a global access solution based on integrated terrestrial-satellite networks.
IEEE COMMUNICATIONS MAGAZINE
(2022)
Article
Oncology
Wencke Walter, Nicole Pfarr, Manja Meggendorfer, Philipp Jost, Torsten Haferlach, Wilko Weichert
Summary: Molecular diagnostics has played a crucial role in precision oncology and has undergone revolutionary developments in recent years. In most cases, it is no longer possible to select treatments for cancer patients without molecular characterization. However, there has been limited scientific research on preanalytical and analytical requirements, and standardization and quality assessment have played a marginal role in the field.
SEMINARS IN CANCER BIOLOGY
(2022)
Review
Pharmacology & Pharmacy
Xiaojuan Wang, Shuzhang Du, Rui Zhang, Xuedong Jia, Ting Yang, Xiaojian Zhang
Summary: Drug-drug cocrystals have advantages of low risk, low cost, and high reward, improving the properties of medicines without chemical modifications. However, reported cases are rare, highlighting opportunities and challenges for their development.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Review
Computer Science, Information Systems
Usman Anwar, Tughrul Arslan, Amir Hussain, Peter Lomax
Summary: This study discusses the association between hearing loss and cognitive decline, as well as the potential future use of microwave technology in care home settings. The efficacy of hearing aids in reversing cognitive decline and dementia is also investigated, along with the interconnection between hearing loss, cognitive load, and neurodegeneration.
Review
Computer Science, Information Systems
Haiwei Dong, Ali Munir, Hanine Tout, Yashar Ganjali
Summary: Data center network (DCN) serves as the backbone for many emerging applications, with the complex management requiring automation and intelligent control. Both industry and academia are focusing on bringing intelligence to DCN to address various challenges.
Article
Oncology
Arjan Gower, Wei-Hsun Hsu, Shuo-Tse Hsu, Yisong Wang, Giuseppe Giaccone
MOLECULAR ONCOLOGY
(2016)
Article
Oncology
C. A. Carter, A. Rajan, C. Keen, E. Szabo, S. Khozin, A. Thomas, C. Brzezniak, U. Guha, L. A. Doyle, S. M. Steinberg, L. Xi, M. Raffeld, Y. Tomita, M. J. Lee, S. Lee, J. B. Trepel, K. L. Reckamp, S. Koehler, B. Gitlitz, R. Salgia, D. Gandara, E. Vokes, G. Giaccone
ANNALS OF ONCOLOGY
(2016)
Article
Pharmacology & Pharmacy
Deepa S. Subramaniam, Eiran A. Warner, Giuseppe Giaccone
EXPERT OPINION ON INVESTIGATIONAL DRUGS
(2017)
Article
Oncology
Pasi A. Janne, Alice T. Shaw, D. Ross Camidge, Giuseppe Giaccone, S. Martin Shreeve, Yiyun Tang, Zelanna Goldberg, Jean-Francois Martini, Huiping Xu, Leonard R. James, Benjamin J. Solomon
JOURNAL OF THORACIC ONCOLOGY
(2016)
Article
Oncology
Anna Teresa Alberobello, Yisong Wang, Frans Joseph Beerkens, Fabio Conforti, Justine N. McCutcheon, Guanhua Rao, Mark Raffeld, Jing Liu, Raneen Rahhal, Yu-Wen Zhang, Giuseppe Giaccone
JOURNAL OF THORACIC ONCOLOGY
(2016)
Review
Oncology
William D. Travis, Hisao Asamura, Alexander A. Bankier, Mary Beth Beasley, Frank Detterbeck, Douglas B. Flieder, Jin Mo Goo, Heber MacMahon, David Naidich, Andrew G. Nicholson, Charles A. Powell, Mathias Prokop, Ramon Rami-Porta, Valerie Rusch, Paul van Schil, Yasushi Yatabe
JOURNAL OF THORACIC ONCOLOGY
(2016)
Review
Oncology
Paul A. Bunn, John D. Minna, Alexander Augustyn, Adi F. Gazdar, Youcef Ouadah, Mark A. Krasnow, Anton Berns, Elisabeth Brambilla, Natasha Rekhtman, Pierre P. Massion, Matthew Niederst, Martin Peifer, Jun Yokota, Ramaswamy Govindan, John T. Poirier, Lauren A. Byers, Murry W. Wynes, David G. McFadden, David MacPherson, Christine L. Hann, Anna F. Farago, Caroline Dive, Beverly A. Teicher, Craig D. Peacock, Jane E. Johnson, Melanie H. Cobb, Hans -Guido Wendel, David Spigel, Julien Sage, Ping Yang, M. Catherine Pietanza, Lee M. Krug, John Heymach, Peter Ujhazy, Caicun Zhou, Koichi Goto, Afshin Dowlati, Camilla Laulund Christensen, Keunchil Park, Lawrence H. Einhorn, Martin J. Edelman, Giuseppe Giaccone, David E. Gerber, Ravi Salgia, Taofeek Owonikoko, Shakun Malik, Niki Karachaliou, David R. Gandara, Ben J. Slotman, Fiona Blackhall, Glenwood Goss, Roman Thomas, Charles M. Rudin, Fred R. Hirsch
JOURNAL OF THORACIC ONCOLOGY
(2016)
Article
Oncology
Peter Goldstraw, Kari Chansky, John Crowley, Ramon Rami-Porta, Hisao Asamura, Wilfried E. E. Eberhardt, Andrew G. Nicholson, Patti Groome, Alan Mitchell, Vanessa Bolejack
JOURNAL OF THORACIC ONCOLOGY
(2016)
Article
Oncology
Anish Thomas, Yuanbin Chen, Arlene Berman, David S. Schrump, Giuseppe Giaccone, Ira Pastan, David J. Venzon, David J. Liewehr, Seth M. Steinberg, Markku Miettinen, Raffit Hassan, Arun Rajan
Editorial Material
Oncology
Stephen V. Liu, Giuseppe Giaccone
NATURE REVIEWS CLINICAL ONCOLOGY
(2016)
Article
Oncology
Rong An, Yisong Wang, Donna Voeller, Arjan Gower, In-Kyu Kim, Yu-Wen Zhang, Giuseppe Giaccone
Editorial Material
Oncology
Stephen V. Liu, Giuseppe Giaccone
TRANSLATIONAL CANCER RESEARCH
(2016)
Editorial Material
Oncology
Justine N. McCutcheon, Xiaoliang Zhao, Giuseppe Giaccone
TRANSLATIONAL CANCER RESEARCH
(2016)
Editorial Material
Oncology
Charles M. Rudin, Giuseppe Giaccone, Nofisat Ismalla
JOURNAL OF ONCOLOGY PRACTICE
(2016)
Review
Oncology
Chul Kim, Arun Rajan, Pedro A. DeBrito, Giuseppe Giaccone
TRANSLATIONAL LUNG CANCER RESEARCH
(2016)
