Site-specific NMR mapping and time-resolved monitoring of serine and threonine phosphorylation in reconstituted kinase reactions and mammalian cell extracts

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA

(2013) Caroline Smet-Nocca et al.   JOURNAL OF BIOMOLECULAR NMR

Rapid Determination of Multiple Linear Kinase Substrate Motifs by Mass Spectrometry

(2012) Arminja N. Kettenbach et al.   CHEMISTRY & BIOLOGY

Surf the Post-translational Modification Network of p53 Regulation

(2012) Bo Gu et al.   International Journal of Biological Sciences

High dimensional and high resolution pulse sequences for backbone resonance assignment of intrinsically disordered proteins

(2012) Anna Zawadzka-Kazimierczuk et al.   JOURNAL OF BIOMOLECULAR NMR

Cell signaling, post-translational protein modifications and NMR spectroscopy

(2012) Francois-Xavier Theillet et al.   JOURNAL OF BIOMOLECULAR NMR

Speeding up sequence specific assignment of IDPs

(2012) Wolfgang Bermel et al.   JOURNAL OF BIOMOLECULAR NMR

Occurrence and Detection of Phosphopeptide Isomers in Large-Scale Phosphoproteomics Experiments

(2012) Mathieu Courcelles et al.   JOURNAL OF PROTEOME RESEARCH

Proteomics in chromatin biology and epigenetics: Elucidation of post-translational modifications of histone proteins by mass spectrometry

(2012) Simone Sidoli et al.   Journal of Proteomics

Site-Specific Mapping and Time-Resolved Monitoring of Lysine Methylation by High-Resolution NMR Spectroscopy

(2012) François-Xavier Theillet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ordered Phosphorylation Events in Two Independent Cascades of the PTEN C-tail Revealed by NMR

(2012) Florence Cordier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FLEXIQinase, a mass spectrometry–based assay, to unveil multikinase mechanisms

(2012) Sasha A Singh et al.   NATURE METHODS

Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events

(2012) Stamatios Liokatis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3′-splice site recognition

(2012) Yun Zhang et al.   NUCLEIC ACIDS RESEARCH

Integrin β3 Crosstalk with VEGFR Accommodating Tyrosine Phosphorylation as a Regulatory Switch

(2012) Xiaoxia Z. West et al.   PLoS One

Site-specific degree of phosphorylation in proteins measured by liquid chromatography-electrospray mass spectrometry

(2012) Martin E. Boehm et al.   PROTEOMICS

Chasing Phosphohistidine, an Elusive Sibling in the Phosphoamino Acid Family

(2011) Jung-Min Kee et al.   ACS Chemical Biology

Advances in Quantitative Phosphoproteomics

(2011) Carol L. Nilsson   ANALYTICAL CHEMISTRY

Facile Identification of Phosphorylation Sites in Peptides by Radical Directed Dissociation

(2011) Jolene K. Diedrich et al.   ANALYTICAL CHEMISTRY

Protein kinase biochemistry and drug discovery

(2011) Phillip A. Schwartz et al.   BIOORGANIC CHEMISTRY

Probing the kinome in real time with fluorescent peptides

(2011) Juan A. González-Vera   CHEMICAL SOCIETY REVIEWS

Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays

(2011) Ina Bock et al.   Epigenetics

Quantitative phosphoproteomics strategies for understanding protein kinase-mediated signal transduction pathways

(2011) Hidetaka Kosako et al.   Expert Review of Proteomics

Breaking the histone code with quantitative mass spectrometry

(2011) Laura-Mae P Britton et al.   Expert Review of Proteomics

Tyrosine Phosphorylation as a Conformational Switch

(2011) Lalit Deshmukh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5D 13C-detected experiments for backbone assignment of unstructured proteins with a very low signal dispersion

(2011) Jiří Nováček et al.   JOURNAL OF BIOMOLECULAR NMR

Paramagnetic relaxation enhancement to improve sensitivity of fast NMR methods: application to intrinsically disordered proteins

(2011) François-Xavier Theillet et al.   JOURNAL OF BIOMOLECULAR NMR

Universal and Confident Phosphorylation Site Localization Using phosphoRS

(2011) Thomas Taus et al.   JOURNAL OF PROTEOME RESEARCH

Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions

(2011) S. Prabakaran et al.   Molecular Systems Biology

Absolute quantification of protein and post-translational modification abundance with stable isotope–labeled synthetic peptides

(2011) Arminja N Kettenbach et al.   Nature Protocols

Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau

(2011) Isabelle Landrieu et al.   PLoS One

Peptide arrays for kinome analysis: New opportunities and remaining challenges

(2011) Ryan Arsenault et al.   PROTEOMICS

Advances in automated NMR protein structure determination

(2011) Paul Guerry et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Mapping in vivo signal transduction defects by phosphoproteomics

(2011) Taras Stasyk et al.   TRENDS IN MOLECULAR MEDICINE

Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database

(2011) George A. Khoury et al.   Scientific Reports

Cooperativity within proximal phosphorylation sites is revealed from large-scale proteomics data

(2010) Regev Schweiger et al.   Biology Direct

Nonessential Sites Improve Phosphorylation Switch

(2010) Liming Wang et al.   BIOPHYSICAL JOURNAL

A Combination of Multisite Phosphorylation and Substrate Sequestration Produces Switchlike Responses

(2010) Xinfeng Liu et al.   BIOPHYSICAL JOURNAL

Influence of Combinatorial Histone Modifications on Antibody and Effector Protein Recognition

(2010) Stephen M. Fuchs et al.   CURRENT BIOLOGY

Systems-wide proteomic characterization of combinatorial post-translational modification patterns

(2010) Nicolas L Young et al.   Expert Review of Proteomics

Pseudo-4D triple resonance experiments to resolve HN overlap in the backbone assignment of unfolded proteins

(2010) Ireena Bagai et al.   JOURNAL OF BIOMOLECULAR NMR

Simultaneous Detection of Protein Phosphorylation and Acetylation by High-Resolution NMR Spectroscopy

(2010) Stamatios Liokatis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Post-translational modifications in signal integration

(2010) Yonathan Lissanu Deribe et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An assessment of histone-modification antibody quality

(2010) Thea A Egelhofer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PHOSIDA 2011: the posttranslational modification database

(2010) F. Gnad et al.   NUCLEIC ACIDS RESEARCH

Are genuine changes in protein expression being overlooked? Reassessing Western blotting

(2009) Janelle P. Mollica et al.   ANALYTICAL BIOCHEMISTRY

The Current Status of Drug Discovery Against the Human Kinome

(2009) Richard M. Eglen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Isoform specific phosphorylation of p53 by protein kinase CK1

(2009) Andrea Venerando et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tyrosine phosphorylation: thirty years and counting

(2009) Tony Hunter   CURRENT OPINION IN CELL BIOLOGY

Multisite protein phosphorylation - from molecular mechanisms to kinetic models

(2009) Carlos Salazar et al.   FEBS Journal

From Promiscuity to Precision: Protein Phosphatases Get a Makeover

(2009) David M. Virshup et al.   MOLECULAR CELL

Targeting Protein Serine/Threonine Phosphatases for Drug Development

(2009) J. L. McConnell et al.   MOLECULAR PHARMACOLOGY

Unlimited multistability in multisite phosphorylation systems

(2009) Matthew Thomson et al.   NATURE

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

(2009) Kazuishi Kubota et al.   NATURE BIOTECHNOLOGY

A complex barcode underlies the heterogeneous response of p53 to stress

(2008) Fiona Murray-Zmijewski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In situ observation of protein phosphorylation by high-resolution NMR spectroscopy

(2008) Philipp Selenko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53

(2008) T. S. Wong et al.   NUCLEIC ACIDS RESEARCH