Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs

Parallel Functional Activity Profiling Reveals Valvulopathogens Are Potent 5-Hydroxytryptamine2B Receptor Agonists: Implications for Drug Safety Assessment

(2009) X.-P. Huang et al.   MOLECULAR PHARMACOLOGY

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

A chemical-genetic approach to study G protein regulation of β cell function in vivo

(2009) Jean-Marc Guettier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In the light of directed evolution: Pathways of adaptive protein evolution

(2009) J. D. Bloom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering GPCR signaling pathways with RASSLs

(2008) Bruce R Conklin et al.   NATURE METHODS

Engineered GPCRs as Tools to Modulate Signal Transduction

(2008) Ying Pei et al.   PHYSIOLOGY