Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

Human sensory neurons: Membrane properties and sensitization by inflammatory mediators

(2014) Steve Davidson et al.   PAIN

Potentiation of the Transient Receptor Potential Vanilloid 1 Channel Contributes to Pruritogenesis in a Rat Model of Liver Disease

(2013) Majedeline Belghiti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small-Fiber Neuropathy Nav1.8 Mutation Shifts Activation to Hyperpolarized Potentials and Increases Excitability of Dorsal Root Ganglion Neurons

(2013) J. Huang et al.   JOURNAL OF NEUROSCIENCE

Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

(2013) Jackson Sandoe et al.   NATURE NEUROSCIENCE

Remodeling Neurodegeneration: Somatic Cell Reprogramming-Based Models of Adult Neurological Disorders

(2013) Liang Qiang et al.   NEURON

Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons

(2013) L. George et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia

(2012) Paula Dietrich et al.   HUMAN MOLECULAR GENETICS

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

(2012) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

(2012) Robert E Sorge et al.   NATURE MEDICINE

Nav1.7-related small fiber neuropathy: Impaired slow-inactivation and DRG neuron hyperexcitability

(2012) C. Han et al.   NEUROLOGY

BioGPS and MyGene.info: organizing online, gene-centric information

(2012) Chunlei Wu et al.   NUCLEIC ACIDS RESEARCH

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic Neurons

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

Induction of human neuronal cells by defined transcription factors

(2011) Zhiping P. Pang et al.   NATURE

HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain

(2011) E. C. Emery et al.   SCIENCE

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

Sustained blockade of neurotrophin receptors TrkA, TrkB and TrkC reduces non-malignant skeletal pain but not the maintenance of sensory and sympathetic nerve fibers

(2010) Joseph R. Ghilardi et al.   BONE

Sox1 Is Required for the Specification of a Novel p2-Derived Interneuron Subtype in the Mouse Ventral Spinal Cord

(2010) H. Panayi et al.   JOURNAL OF NEUROSCIENCE

Sensitization of Capsaicin and Icilin Responses in Oxaliplatin Treated Adult Rat DRG Neurons

(2010) Uma Anand et al.   Molecular Pain

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Overcoming obstacles to developing new analgesics

(2010) Clifford J Woolf   NATURE MEDICINE

Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation

(2010) Iain M Dykes et al.   Neural Development

Channelopathic Pain: A Growing but Still Small List of Model Disorders

(2010) Stephen G. Waxman   NEURON

Pain perception is altered by a nucleotide polymorphism in SCN9A

(2010) F. Reimann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

(2008) Yunfu Sun et al.   NATURE NEUROSCIENCE

Neuronal intermediate filament expression in rat dorsal root ganglia sensory neurons: An in vivo and in vitro study

(2008) M. Fornaro et al.   NEUROSCIENCE