Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance
出版年份 2013 全文链接
标题
Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance
作者
关键词
-
出版物
NATURE NEUROSCIENCE
Volume 16, Issue 5, Pages 562-570
出版商
Springer Nature
发表日期
2013-03-23
DOI
10.1038/nn.3367
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum
- (2012) Richard Grondin et al. BRAIN
- Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes
- (2012) The HD iPSC Consortium Cell Stem Cell
- TR-FRET-Based Duplex Immunoassay Reveals an Inverse Correlation of Soluble and Aggregated Mutant huntingtin in Huntington's Disease
- (2012) Barbara Baldo et al. CHEMISTRY & BIOLOGY
- Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression
- (2012) Andreas Weiss et al. JOURNAL OF CLINICAL INVESTIGATION
- Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
- (2012) Dyna I. Shirasaki et al. NEURON
- FAT10 Protein Binds to Polyglutamine Proteins and Modulates Their Solubility
- (2011) Yu Nagashima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila
- (2010) S. Zhang et al. GENETICS
- Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease
- (2010) Christian Landles et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse β cells
- (2010) Chong Wee Liew et al. JOURNAL OF CLINICAL INVESTIGATION
- The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
- (2010) Maria Filimonenko et al. MOLECULAR CELL
- Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein
- (2010) Peter O Bauer et al. NATURE BIOTECHNOLOGY
- Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease
- (2010) John P. Miller et al. NEURON
- Single-step detection of mutant huntingtin in animal and human tissues: A bioassay for Huntington’s disease
- (2009) Andreas Weiss et al. ANALYTICAL BIOCHEMISTRY
- Sustained effects of nonallele-specificHuntingtinsilencing
- (2009) Valérie Drouet et al. ANNALS OF NEUROLOGY
- Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy
- (2009) Peter O. Bauer et al. Autophagy
- An Efficient and Reversible Transposable System for Gene Delivery and Lineage-Specific Differentiation in Human Embryonic Stem Cells
- (2009) Arnaud Lacoste et al. Cell Stem Cell
- IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
- (2009) Leslie Michels Thompson et al. JOURNAL OF CELL BIOLOGY
- Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease
- (2009) Antonio Valencia et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction
- (2009) Andreas Weiss et al. Molecular Neurodegeneration
- Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice
- (2009) Ryan L Boudreau et al. MOLECULAR THERAPY
- An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
- (2009) Teresa A. Soucy et al. NATURE
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
- (2009) Stuart M Chambers et al. NATURE BIOTECHNOLOGY
- RNAi Screening in Drosophila Cells Identifies New Modifiers of Mutant Huntingtin Aggregation
- (2009) Joanna Doumanis et al. PLoS One
- Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity
- (2009) S. Subramaniam et al. SCIENCE
- Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
- (2008) S Sarkar et al. CELL DEATH AND DIFFERENTIATION
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