Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change

Presenilins and  -Secretase: Structure, Function, and Role in Alzheimer Disease

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Distinct Neuronal Coding Schemes in Memory Revealed by Selective Erasure of Fast Synchronous Synaptic Transmission

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Compartmentalization of the GABAB Receptor Signaling Complex Is Required for Presynaptic Inhibition at Hippocampal Synapses

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Preventive and therapeutic types of environmental enrichment counteract beta amyloid pathology by different molecular mechanisms

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Novel Research Horizons for Presenilins and γ-Secretases in Cell Biology and Disease

(2010) Bart De Strooper et al.   Annual Review of Cell and Developmental Biology

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Basal GABA Regulates GABABR Conformation and Release Probability at Single Hippocampal Synapses

(2010) Tal Laviv et al.   NEURON

The Genetics of Alzheimer Disease: Back to the Future

(2010) Lars Bertram et al.   NEURON

Amyloid beta from axons and dendrites reduces local spine number and plasticity

(2009) Wei Wei et al.   NATURE NEUROSCIENCE

Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses

(2009) Efrat Abramov et al.   NATURE NEUROSCIENCE

Allosteric Modulation of PS1/γ-Secretase Conformation Correlates with Amyloid β42/40 Ratio

(2009) Kengo Uemura et al.   PLoS One

Molecular genetics of Alzheimer's disease: An update

(2008) Nathalie Brouwers et al.   ANNALS OF MEDICINE

High frequency action potential bursts (≥ 100 Hz) in L2/3 and L5B thick tufted neurons in anaesthetized and awake rat primary somatosensory cortex

(2008) C. P. J. De Kock et al.   JOURNAL OF PHYSIOLOGY-LONDON

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON