Superior Intratumoral Penetration of Paclitaxel Nanodots Strengthens Tumor Restriction and Metastasis Prevention

Co-Delivery of Doxorubicin and siRNA with Reduction and pH Dually Sensitive Nanocarrier for Synergistic Cancer Therapy

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A Dual-Responsive Mesoporous Silica Nanoparticle for Tumor-Triggered Targeting Drug Delivery

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Molecular structure matters: PEG-b-PLA nanoparticles with hydrophilicity and deformability demonstrate their advantages for high-performance delivery of anti-cancer drugs

(2013) Zhanguo Yue et al.   Journal of Materials Chemistry B

Tumor-Penetrating Peptides

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The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

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Sphere formation reverses the metastatic and cancer stem cell phenotype of the murine mammary tumour 4T1, independently of the putative cancer stem cell marker Sca-1

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De Novo Design of a Tumor-Penetrating Peptide

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Improvement of drug safety by the use of lipid-based nanocarriers

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Targeted Delivery of Insoluble Cargo (Paclitaxel) by PEGylated Chitosan Nanoparticles Grafted with Arg-Gly-Asp (RGD)

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Cancer stem cells and drug resistance: the potential of nanomedicine

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The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery

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Hallmarks of Cancer: The Next Generation

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Triple negative breast cancer: unmet medical needs

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Pulsed Ultrasound Enhances Nanoparticle Penetration into Breast Cancer Spheroids

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Galactosylated nanocrystallites of insoluble anticancer drug for liver-targeting therapy: anin vitroevaluation

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Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

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A nanoscale drug-entrapment strategy for hydrogel-based systems for the delivery of poorly soluble drugs

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Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

(2009) Kazuki N. Sugahara et al.   CANCER CELL

Preparation of drug nanocrystals by controlled crystallization: Application of a 3-way nozzle to prevent premature crystallization for large scale production

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Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Imagable 4T1 model for the study of late stage breast cancer

(2008) Kai Tao et al.   BMC CANCER

Characteristics of polymers enabling nano-comminution of water-insoluble drugs

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Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular Spheroids

(2008) Dario Barbone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanoparticle-mediated cellular response is size-dependent

(2008) Wen Jiang et al.   Nature Nanotechnology

Design of a Tumor-Homing Cell-Penetrating Peptide

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