期刊
NATURE MEDICINE
卷 24, 期 8, 页码 1081-1081出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41591-018-0150-3
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Concerns about potential unintended DNA changes that might accidentally arise from CRISPR gene editing have emerged to varying degrees with the advent of the technology. As new therapies move from bench to bedside, scientists need to redouble their efforts to document the spectrum of these off-target effects while also acknowledging the reality that a certain degree of risk is embedded in many promising and successful medical therapies.
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