Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

Variation in the Kozak sequence of WNT16 results in an increased translation and is associated with osteoporosis related parameters

(2013) Gretl Hendrickx et al.   BONE

Lipoproteins are an important bacterial component responsible for bone destruction through the induction of osteoclast differentiation and activation

(2013) Jiseon Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt16 is Involved in Intramembranous Ossification and Suppresses Osteoblast Differentiation Through the Wnt/β-Catenin Pathway

(2013) Zheng Jiang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Missense polymorphisms of the WNT16 gene are associated with bone mass, hip geometry and fractures

(2013) C. García-Ibarbia et al.   OSTEOPOROSIS INTERNATIONAL

Use of a Molecular Genetic Platform Technology to Produce Human Wnt Proteins Reveals Distinct Local and Distal Signaling Abilities

(2013) Jennifer L. Green et al.   PLoS One

Estrogen receptor-  in osteocytes is important for trabecular bone formation in male mice

(2013) S. H. Windahl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoclast progenitor cells present in significant amounts in mouse calvarial osteoblast isolations and osteoclastogenesis increased by BMP-2

(2012) Susanne Granholm et al.   BONE

Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche

(2012) Ryohichi Sugimura et al.   CELL

Meta-analysis of genome-wide studies identifiesWNT16andESR1SNPs associated with bone mineral density in premenopausal women

(2012) Daniel L Koller et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Update on Bone Anabolics in Osteoporosis Treatment: Rationale, Current Status, and Perspectives

(2012) Roland Baron et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

Wntless functions in mature osteoblasts to regulate bone mass

(2012) Z. Zhong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus

(2012) Carolina Medina-Gomez et al.   PLoS Genetics

WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk

(2012) Hou-Feng Zheng et al.   PLoS Genetics

Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir

(2011) Francisco Santiago et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by  -Catenin

(2011) W. Wei et al.   MOLECULAR AND CELLULAR BIOLOGY

Glucocorticoids Suppress Bone Formation by Attenuating Osteoblast Differentiation via the Monomeric Glucocorticoid Receptor

(2010) Alexander Rauch et al.   Cell Metabolism

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin antibody treatment enhances metaphyseal bone healing in rats

(2010) Fredrik Agholme et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells

(2010) Jennifer R Stevens et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study

(2010) Roger MD Zebaze et al.   LANCET

Osteocyte Wnt/ -Catenin Signaling Is Required for Normal Bone Homeostasis

(2010) I. Kramer et al.   MOLECULAR AND CELLULAR BIOLOGY

Adenomatous polyposis coli-mediated control of β-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors

(2009) Razvan L Miclea et al.   BMC DEVELOPMENTAL BIOLOGY

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

(2009) Christa Maes et al.   EMBO JOURNAL

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Wnt Signaling from Development to Disease: Insights from Model Systems

(2009) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Hip Fractures and the Contribution of Cortical Versus Trabecular Bone to Femoral Neck Strength

(2008) Gerold Holzer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase

(2008) Yan Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Liposomal Packaging Generates Wnt Protein with In Vivo Biological Activity

(2008) Nathan T. Morrell et al.   PLoS One

Stainless steel screws coated with bisphosphonates gave stronger fixation and more surrounding bone. Histomorphometry in rats

(2007) K. Wermelin et al.   BONE