Dysregulation of immune homeostasis in autoimmune diseases

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells

(2011) I. Wollenberg et al.   JOURNAL OF IMMUNOLOGY

Progressive multifocal leukoencephalopathy and natalizumab

(2011) Kerstin Hellwig et al.   JOURNAL OF NEUROLOGY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells

(2011) Dilan Dissanayake et al.   NATURE MEDICINE

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid

(2011) M. Mohamadzadeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice

(2011) M. A. Kriegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Commensal flora and the regulation of inflammatory and autoimmune responses

(2011) Jan Kranich et al.   SEMINARS IN IMMUNOLOGY

Genetic predisposition to autoimmunity – What have we learned?

(2011) Ekta Rai et al.   SEMINARS IN IMMUNOLOGY

Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

(2011) Lars Klareskog et al.   SEMINARS IN IMMUNOLOGY

Tissular Tregs: A unique population of adipose-tissue-resident Foxp3+CD4+ T cells that impacts organismal metabolism

(2011) Daniela Cipolletta et al.   SEMINARS IN IMMUNOLOGY

T cell receptor recognition of self and foreign antigens in the induction of autoimmunity

(2011) Kai W. Wucherpfennig et al.   SEMINARS IN IMMUNOLOGY

External influences on the immune system via activation of the aryl hydrocarbon receptor

(2011) Brigitta Stockinger et al.   SEMINARS IN IMMUNOLOGY

Toll-like receptor driven B cell activation in the induction of systemic autoimmunity

(2011) Nathaniel M. Green et al.   SEMINARS IN IMMUNOLOGY

Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women

(2010) A. Santacruz et al.   BRITISH JOURNAL OF NUTRITION

D'oh! Genes and Environment Cause Crohn's Disease

(2010) John A. Todd   CELL

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

Genetics and Environmental Interactions Shape the Intestinal Microbiome to Promote Inflammatory Bowel Disease Versus Mucosal Homeostasis

(2010) R. Balfour Sartor   GASTROENTEROLOGY

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

T cells and follicular dendritic cells in germinal center B-cell formation and selection

(2010) Carola G. Vinuesa et al.   IMMUNOLOGICAL REVIEWS

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases

(2010) Daniel N. Frank et al.   INFLAMMATORY BOWEL DISEASES

In Vitro Bioconversion of Polyphenols from Black Tea and Red Wine/Grape Juice by Human Intestinal Microbiota Displays Strong Interindividual Variability

(2010) Gabriele Gross et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

(2010) J Ochoa-Repáraz et al.   Mucosal Immunology

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

(2010) Roopali Gandhi et al.   NATURE IMMUNOLOGY

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

(2010) N. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

(2009) Nicholas Simpson et al.   ARTHRITIS AND RHEUMATISM

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Environmental control of Th17 differentiation

(2009) Francisco J. Quintana et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Follicular helper T cells are required for systemic autoimmunity

(2009) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aryl Hydrocarbon Receptor Activation Inhibits In Vitro Differentiation of Human Monocytes and Langerhans Dendritic Cells

(2009) B. Platzer et al.   JOURNAL OF IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

(2009) et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Smad7 Controls Resistance of Colitogenic T Cells to Regulatory T Cell-Mediated Suppression

(2008) Massimo C. Fantini et al.   GASTROENTEROLOGY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells

(2008) Noriyuki Fujikado et al.   NATURE MEDICINE

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

(2008) B. A. Croker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA