Article
Clinical Neurology
Hiwa Mohammadi, Ardalan Aarabi, Mohammad Rezaei, Habibolah Khazaie, Serge Brand
Summary: The study found that individuals with OSAS have significantly lower spindle density in N3 and shorter spindle duration in N2 compared to healthy controls. Furthermore, individuals with mild OSAS showed sleep spindle characteristics more similar to healthy controls, unlike those with moderate and severe OSAS.
FRONTIERS IN NEUROLOGY
(2021)
Article
Surgery
Luigi Schiavo, Roberto Pierro, Carmela Asteria, Pietro Calabrese, Alberto Di Biasio, Ilenia Coluzzi, Lucia Severino, Alessandro Giovanelli, Vincenzo Pilone, Gianfranco Silecchia
Summary: Research assessed the clinical advantage of pre-bariatric surgery CPAP and LCKD in patients with obesity and OSAS.
Article
Clinical Neurology
Chia-Feng Juang, Chih-Yu Wen, Kai-Ming Chang, Yu-Hsuan Chen, Ming-Feng Wu, Wei-Chang Huang
Summary: The study aimed to propose a self-estimation method for predicting obstructive sleep apnea-hypopnea syndrome (OSAHS) using easy-to-obtain physiological features, and the results showed that the explainable fuzzy neural network (EFNN) was the preferred method for predicting moderate-to-severe OSAHS.
Review
Physiology
Jian Sun, Jie He, Zongan Liang
Summary: This meta-analysis explored the association between ocular surface alterations and disease severity in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). The prevalence of floppy eyelid syndrome (FES) and dry eye syndrome was found to be high in OSAHS patients. They also exhibited lower Schirmer 1 value and tear break-up time, as well as higher OSDI scores, corneal staining scores, and meibomian gland loss rates compared to healthy controls. Moreover, there were negative correlations between Schirmer 1 value/tear break-up time and apnea-hypopnea index (AHI), and a positive association between OSDI and AHI.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Adrian Ujin Yap, Madeleine Wan Yong Tan, Sharon Hui Xuan Tan, Ai Ping Chua
Summary: This study examined the temporal relationships between apnea-hypopnea (AH) and sleep bruxism (SB) events and their correlation with respiratory/sleep indexes in patients with obstructive sleep apnea (OSA) and SB. The majority of AH events were unrelated to SB events. When they were related, SB events often occurred after AH events, indicating a specific form of secondary SB triggered by sleep micro-arousals. SB events were associated with total sleep time, but not with the AH index.
CLINICAL ORAL INVESTIGATIONS
(2023)
Review
Health Care Sciences & Services
Sy Duong-Quy, Hoang Nguyen-Huu, Dinh Hoang-Chau-Bao, Si Tran-Duc, Lien Nguyen-Thi-Hong, Thai Nguyen-Duy, Tram Tang-Thi-Thao, Chandat Phan, Khue Bui-Diem, Quan Vu-Tran-Thien, Thu Nguyen-Ngoc-Phuong, Vinh Nguyen-Nhu, Huong Le-Thi-Minh, Timothy Craig
Summary: Obstructive Sleep Apnea (OSA) is a common disease that is often underestimated and undertreated in all age groups. Personalized diagnosis and treatment approaches are necessary for clinical practice due to morphological differences, clinical phenotype diversity, and variations in diagnosis and treatment of OSA in children and adults. Treatment should be based on individual tolerance to sleep-quality-related parameters, the harmful effects of hypoxia on the cardiovascular system, and patients' comorbidities.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Clinical Neurology
Tien Hoang-Anh, Quy Duong-Minh, Nhi Nguyen-Thi-Y, Sy Duong-Quy
Summary: This study aims to assess the prevalence and general characteristics of obstructive sleep apnea syndrome in patients with cerebral infarction and investigate the relationship between obstructive sleep apnea syndrome and the severity of cerebral infarction. The results show that obstructive sleep apnea syndrome is a factor in the prognosis of cerebral infarction and it is important to work with a doctor to diagnose and treat sleep apnea.
FRONTIERS IN NEUROLOGY
(2023)
Article
Critical Care Medicine
Samuel T. Kuna, David M. Reboussin, Elsa S. Strotmeyer, Richard P. Millman, Gary Zammit, Michael P. Walkup, Thomas A. Wadden, Rena R. Wing, F. Xavier Pi-Sunyer, Adam P. Spira, Gary D. Foster
Summary: Intensive lifestyle intervention for weight loss can lead to reduced severity of obstructive sleep apnea in individuals with type 2 diabetes mellitus, and this improvement can be sustained over a 10-year period. The amount of weight loss is related to the improvement in OSA severity, and ILI may play a significant role in this improvement.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Endocrinology & Metabolism
M. Leentjens, Abdulmohsen Alterki, Mohamed Abu-Farha, P. F. N. Bosschieter, CAL. de Raaff, CEE. de Vries, Eman Al Shawaf, Thangavel Alphonse Thanaraj, Irina Al-Khairi, Preethi Cherian, Arshad Channanath, Sina Kavalakatt, B. A. van Wagensveld, N. de Vries, Jehad Abubaker
Summary: This study found significantly increased levels of ANGPTL7 in both the circulation and adipose tissue of patients with OSA, which were associated with increased inflammation and OSA severity. Bariatric surgery was shown to significantly reduce ANGPTL7 levels and improve OSA.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Nevin Fazlioglu, Pelin Uysal, Sinem Durmus, Sibel Yurt, Remise Gelisgen, Hafize Uzun
Summary: This study investigated the relationship between plasma irisin, RBP-4, and adiponectin levels and the severity of OSAS. The results showed that these biomarkers were associated with the disease and could be used for diagnosis in the absence of polysomnography. Patients with an AHI score greater than thirty should be closely monitored for metabolic abnormalities.
Article
Clinical Neurology
Chenyang Li, Yiqing Gao, Weijun Huang, Huajun Xu, Yupu Liu, Jianyin Zou, Huaming Zhu, Xinyi Li, Fangkai Han, Jingjing Liu, Kejia Wu, Hongliang Yi, Jian Guan, Shankai Yin
Summary: The study found that the sleep apnea-specific hypoxic burden (SASHB) can accurately predict and assess obstructive sleep apnea hypopnea syndrome (OSA) and its severity in Han Chinese individuals.
Review
Geriatrics & Gerontology
Yayong Li, Yina Wang
Summary: OSAHS is a common sleep disorder that can negatively impact individuals' quality of life and economic burden, especially in developing countries or economically disadvantaged regions. Scholars suggest that OSAHS may be a novel potential risk for aging, highlighting the importance of further understanding its pathophysiological mechanism and role in the aging process.
Article
Health Care Sciences & Services
Christopher Seifen, Johannes Pordzik, Katharina Bahr, Lisa Grosse-Brueggemann, Katharina Ludwig, Berit Hackenberg, Christoph Matthias, Perikles Simon, Haralampos Gouveris
Summary: Evidence suggests that the apnea-hypopnea index (AHI) increases with aging, especially in males. However, the impact of aging on sleep-related metrics, specifically AHI, has been less studied in different gender-specific subpopulations while considering confounding factors such as obstructive sleep apnea-related comorbidities and body mass index (BMI). A retrospective analysis of 186 first-time polysomnographic recordings and medical files was conducted, forming six groups based on age and gender. The older mixed-gender and female cohorts showed significantly higher AHI, apnea-index, and hypopnea-index values. Within the older male cohort, AHI and apnea-index were also significantly higher. No significant differences in BMI were found. The older male cohort had significantly more patients with arterial hypertension, diabetes mellitus, cardiovascular diseases, and chronic mental health disorders. Conversely, the female subpopulation showed no significant differences in these comorbidities. In conclusion, sleep PSG-parameters increased in older subpopulations, possibly due to the accumulation of comorbidities in older males but not in females.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Health Care Sciences & Services
Geetha Kandasamy, Tahani Almeleebia
Summary: This study aimed to assess OSA and the relationship between AHI and polysomnographic characteristics in OSA patients. The results showed a significant prevalence of obesity and high frequency of OSA in men, with polysomnography being the primary method for early detection and treatment of the condition.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Guo-hui Zeng, Guo Xu, Hong-yu Liu, Zhong Gao
Summary: This study evaluated the correlation between mean platelet volume (MPV) and obstructive sleep apnea-hypopnea syndrome (OSAHS) in children, and found that MPV can be used as an auxiliary diagnostic index to judge the severity of OSAHS and the degree of hypoxia in children.