Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity
出版年份 2018 全文链接
标题
Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity
作者
关键词
-
出版物
NATURE IMMUNOLOGY
Volume 19, Issue 9, Pages 986-1000
出版商
Springer Nature America, Inc
发表日期
2018-08-15
DOI
10.1038/s41590-018-0182-3
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Spatial distribution and function of T follicular regulatory cells in human lymph nodes
- (2018) Ismail Sayin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
- (2017) Jonatan Ersching et al. IMMUNITY
- Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
- (2017) Tanya I. Coulter et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Abnormal B-cell maturation in the bone marrow of patients with germline mutations in PIK3CD
- (2017) Alina E. Dulau Florea et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria
- (2017) Jean-Nicolas Schickel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Akkermansia muciniphila and its role in regulating host functions
- (2017) Muriel Derrien et al. MICROBIAL PATHOGENESIS
- Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells
- (2017) Mara Compagno et al. NATURE
- Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila
- (2017) Patrice D. Cani et al. Frontiers in Microbiology
- T follicular helper cells in human autoimmunity
- (2016) Hideki Ueno CURRENT OPINION IN IMMUNOLOGY
- Regulation of Autoimmunity by the Microbiome
- (2016) Carlos R. Zárate-Bladés et al. DNA AND CELL BIOLOGY
- Germinal Center B Cell Dynamics
- (2016) Luka Mesin et al. IMMUNITY
- mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
- (2016) Hu Zeng et al. IMMUNITY
- Peyer's patches: organizing B-cell responses at the intestinal frontier
- (2016) Andrea Reboldi et al. IMMUNOLOGICAL REVIEWS
- T follicular regulatory cells
- (2016) Peter T. Sage et al. IMMUNOLOGICAL REVIEWS
- DADA2: High-resolution sample inference from Illumina amplicon data
- (2016) Benjamin J Callahan et al. NATURE METHODS
- Antigen-affinity controls pre-germinal center B cell selection by promoting Mcl-1 induction through BAFF receptor signaling
- (2016) Felix M. Wensveen et al. Scientific Reports
- Somatic mutations and affinity maturation are impaired by excessive numbers of T follicular helper cells and restored by Treg cells or memory T cells
- (2015) Silvia Preite et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program
- (2015) David Dominguez-Sola et al. IMMUNITY
- PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones
- (2015) Sandrine Sander et al. IMMUNITY
- ICOS Coreceptor Signaling Inactivates the Transcription Factor FOXO1 to Promote Tfh Cell Differentiation
- (2015) Erica L. Stone et al. IMMUNITY
- Strategically Localized Dendritic Cells Promote Rapid T Cell Responses to Lymph-Borne Particulate Antigens
- (2015) Michael Y. Gerner et al. IMMUNITY
- The bilateral responsiveness between intestinal microbes and IgA
- (2015) Andrew J. Macpherson et al. TRENDS IN IMMUNOLOGY
- Lymph-Node Resident CD8α+ Dendritic Cells Capture Antigens from Migratory Malaria Sporozoites and Induce CD8+ T Cell Responses
- (2015) Andrea J. Radtke et al. PLoS Pathogens
- Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease
- (2014) Noah W. Palm et al. CELL
- Foxp3+ T Cells Regulate Immunoglobulin A Selection and Facilitate Diversification of Bacterial Species Responsible for Immune Homeostasis
- (2014) Shimpei Kawamoto et al. IMMUNITY
- ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism
- (2014) Michele Proietti et al. IMMUNITY
- Mutations in PIK3CD Can Cause Hyper IgM Syndrome (HIGM) Associated with Increased Cancer Susceptibility
- (2014) M. C. Crank et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells
- (2014) Julio Gomez-Rodriguez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Phenotype and functions of memory Tfh cells in human blood
- (2014) Nathalie Schmitt et al. TRENDS IN IMMUNOLOGY
- Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype
- (2013) Dirk Baumjohann et al. IMMUNITY
- Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure
- (2013) Jing He et al. IMMUNITY
- Control of TFH cell numbers: why and how?
- (2013) Alvin Pratama et al. IMMUNOLOGY AND CELL BIOLOGY
- Mcl-1 is essential for the survival of plasma cells
- (2013) Victor Peperzak et al. NATURE IMMUNOLOGY
- Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency
- (2013) Carrie L Lucas et al. NATURE IMMUNOLOGY
- Phosphoinositide 3-Kinase Gene Mutation Predisposes to Respiratory Infection and Airway Damage
- (2013) I. Angulo et al. SCIENCE
- B Cell-Intrinsic MyD88 Signaling Prevents the Lethal Dissemination of Commensal Bacteria during Colonic Damage
- (2012) Donna Kirkland et al. IMMUNITY
- Histo-Cytometry: A Method for Highly Multiplex Quantitative Tissue Imaging Analysis Applied to Dendritic Cell Subset Microanatomy in Lymph Nodes
- (2012) Michael Y. Gerner et al. IMMUNITY
- Through a glass less darkly: apoptosis and the germinal center response to antigen
- (2012) Victor Peperzak et al. IMMUNOLOGICAL REVIEWS
- Novel Foxo1-dependent transcriptional programs control Treg cell function
- (2012) Weiming Ouyang et al. NATURE
- Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter
- (2010) Gabriel D. Victora et al. CELL
- Foxo1 regulates marginal zone B-cell development
- (2010) Jing Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction
- (2010) J. Rolf et al. JOURNAL OF IMMUNOLOGY
- Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory
- (2010) I. Vikstrom et al. SCIENCE
- PI3 Kinase Signals BCR-Dependent Mature B Cell Survival
- (2009) Lakshmi Srinivasan et al. CELL
- Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
- (2009) E. Slack et al. SCIENCE
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