A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells

Type I IFN Induces Binding of STAT1 to Bcl6: Divergent Roles of STAT Family Transcription Factors in the T Follicular Helper Cell Genetic Program

(2014) S. Nakayamada et al.   JOURNAL OF IMMUNOLOGY

The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells

(2014) Nengming Xiao et al.   NATURE IMMUNOLOGY

New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes

(2013) Karen L Bunting et al.   CURRENT OPINION IN IMMUNOLOGY

Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells

(2013) Jianmei W. Leavenworth et al.   JOURNAL OF CLINICAL INVESTIGATION

TRAF3 regulates the effector function of regulatory T cells and humoral immune responses

(2013) Jae-Hoon Chang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: STAT1 Is Required for IL-6-Mediated Bcl6 Induction for Early Follicular Helper Cell Differentiation

(2013) Y. S. Choi et al.   JOURNAL OF IMMUNOLOGY

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility

(2013) Heping Xu et al.   NATURE

MicroRNAs of the miR-17∼92 family are critical regulators of TFH differentiation

(2013) Seung Goo Kang et al.   NATURE IMMUNOLOGY

Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms

(2013) Chuanxin Huang et al.   NATURE IMMUNOLOGY

Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells

(2013) J. Kronke et al.   SCIENCE

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood

(2012) Peter T Sage et al.   NATURE IMMUNOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

(2011) Youn Soo Choi et al.   IMMUNITY

Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone

(2011) Steven M. Kerfoot et al.   IMMUNITY

Cutting Edge: Distinct Waves of BCL6 Expression during T Follicular Helper Cell Development

(2011) D. Baumjohann et al.   JOURNAL OF IMMUNOLOGY

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Mobilization of natural killer cells inhibits development of collagen-induced arthritis

(2011) J. W. Leavenworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular osteopontin (iOPN) and immunity

(2010) Makoto Inoue et al.   IMMUNOLOGIC RESEARCH

Signaling Pathways in T Follicular Helper Cells

(2010) J. Rolf et al.   JOURNAL OF IMMUNOLOGY

Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction

(2010) J. Rolf et al.   JOURNAL OF IMMUNOLOGY

Inhibition of follicular T-helper cells by CD8+ regulatory T cells is essential for self tolerance

(2010) Hye-Jung Kim et al.   NATURE

Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression

(2010) Elke Glasmacher et al.   NATURE IMMUNOLOGY

Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation

(2010) Shane Crotty et al.   NATURE IMMUNOLOGY

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–binding protein-1 to modulate the unfolded protein response

(2010) Jonathon N Winnay et al.   NATURE MEDICINE

The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation

(2010) Sang Won Park et al.   NATURE MEDICINE

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML

(2009) J. A. Powell et al.   BLOOD

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas

(2009) Leandro C Cerchietti et al.   NATURE MEDICINE

Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase

(2009) M. Gigoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Pathway analysis of primary central nervous system lymphoma

(2008) H. W. Tun et al.   BLOOD

Engagement of the Type I Interferon Receptor on Dendritic Cells Inhibits T Helper 17 Cell Development: Role of Intracellular Osteopontin

(2008) Mari L. Shinohara et al.   IMMUNITY

The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+cells

(2008) Sokol Haxhinasto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells

(2008) M. L. Shinohara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA