Diversification of TAM receptor tyrosine kinase function

An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo

(2014) Manikandan Subramanian et al.   JOURNAL OF CLINICAL INVESTIGATION

Different expression patterns and clinical significance of mAxl and sAxl in systemic lupus erythematosus

(2014) H Zhu et al.   LUPUS

Tim4- and MerTK-Mediated Engulfment of Apoptotic Cells by Mouse Resident Peritoneal Macrophages

(2014) C. Nishi et al.   MOLECULAR AND CELLULAR BIOLOGY

Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance

(2013) María Casanova-Acebes et al.   CELL

Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors

(2013) Suchita Bhattacharyya et al.   Cell Host & Microbe

Plasma concentrations of sAxl are associated with severe preeclampsia

(2013) Xijing Liu et al.   CLINICAL BIOCHEMISTRY

T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response

(2013) Eugenio A. Carrera Silva et al.   IMMUNITY

Circulating Growth Arrest-Specific 6 Protein Is Associated With Adiposity, Systemic Inflammation, and Insulin Resistance Among Overweight and Obese Adolescents

(2013) Fone-Ching Hsiao et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

MERTK receptor tyrosine kinase is a therapeutic target in melanoma

(2013) Jennifer Schlegel et al.   JOURNAL OF CLINICAL INVESTIGATION

Plasma Concentrations Predict Aortic Expression of Growth-Arrest-Specific Protein 6 in Patients Undergoing Coronary Artery Bypass Grafting

(2013) Chien-Hsing Lee et al.   PLoS One

Biology of the TAM Receptors

(2013) G. Lemke   Cold Spring Harbor Perspectives in Biology

Therapeutic efficacy of Tyro3, Axl, and Mer tyrosine kinase agonists in collagen-induced arthritis

(2012) B. T. van den Brand et al.   ARTHRITIS AND RHEUMATISM

The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry

(2012) Laurent Meertens et al.   Cell Host & Microbe

Genetic Dissection of TAM Receptor-Ligand Interaction in Retinal Pigment Epithelial Cell Phagocytosis

(2012) Tal Burstyn-Cohen et al.   NEURON

Essential Role of E3 Ubiquitin Ligase Activity in Cbl-b-Regulated T Cell Functions

(2011) M. Paolino et al.   JOURNAL OF IMMUNOLOGY

TAM receptors and the clearance of apoptotic cells

(2010) Greg Lemke et al.   Annals of the New York Academy of Sciences

R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

(2010) S. J. Holland et al.   CANCER RESEARCH

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

TAM receptor signaling and autoimmune disease

(2010) Carla V Rothlin et al.   CURRENT OPINION IN IMMUNOLOGY

Lipopolysaccharide inhibits macrophage phagocytosis of apoptotic neutrophils by regulating the production of tumour necrosis factor α and growth arrest-specific gene 6

(2010) Xueying Feng et al.   IMMUNOLOGY

Impaired Apoptotic Cell Clearance in the Germinal Center by Mer-Deficient Tingible Body Macrophages Leads to Enhanced Antibody-Forming Cell and Germinal Center Responses

(2010) Z. S. M. Rahman et al.   JOURNAL OF IMMUNOLOGY

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies

(2010) X Ye et al.   ONCOGENE

Plasma concentrations of growth arrest specific protein 6 and the soluble form of its tyrosine kinase receptor Axl as markers of large abdominal aortic aneurysms

(2009) Carl Ekman et al.   CLINICAL BIOCHEMISTRY

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

(2009) Noelia A-Gonzalez et al.   IMMUNITY

A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester

(2009) Michael Miksa et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages

(2009) A. McColl et al.   JOURNAL OF IMMUNOLOGY

Discovery ofN-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

(2009) Gretchen M. Schroeder et al.   JOURNAL OF MEDICINAL CHEMISTRY

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

(2009) Lata Mukundan et al.   NATURE MEDICINE