IL-1 signaling in atherosclerosis: sibling rivalry

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

(2013) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis

(2013) Stefan Freigang et al.   NATURE IMMUNOLOGY

Regulation of interleukin 1α secretion by inflammasomes: Table 1

(2012) Amir S Yazdi et al.   ANNALS OF THE RHEUMATIC DISEASES

Effect of interleukin 1β inhibition in cardiovascular disease

(2012) Arman Qamar et al.   CURRENT OPINION IN LIPIDOLOGY

Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

(2011) Vinay Bhaskar et al.   ATHEROSCLEROSIS

Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1α

(2011) Yehuda Kamari et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis

(2011) Stefan Freigang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice

(2011) Matthew R. Alexander et al.   JOURNAL OF CLINICAL INVESTIGATION

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

(2011) P Menu et al.   Cell Death & Disease

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One