期刊
NATURE IMMUNOLOGY
卷 12, 期 10, 页码 929-930出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ni.2118
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The sensing of pathogen-associated DNA in the cytoplasm is an important trigger of host-defense responses that include the production of type I interferon. A new study suggests that the DExDc helicase DDX41 may function in dendritic cells as a DNA sensor to activate STING-dependent innate immune responses.
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