Dystrophin is a tumor suppressor in human cancers with myogenic programs

Gene Replacement Therapies for Duchenne Muscular Dystrophy Using Adeno-Associated Viral Vectors

(2012) Jane T. Seto et al.   CURRENT GENE THERAPY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

(2012) Stefan M. Gehrig et al.   NATURE

p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors

(2012) Joern Henze et al.   PLoS One

Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma

(2012) B. Edris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sarcomas in TP53 germline mutation carriers

(2011) Simona Ognjanovic et al.   CANCER

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

(2011) Sebahattin Cirak et al.   LANCET

Dystrophin Dp71: The Smallest but Multifunctional Product of the Duchenne Muscular Dystrophy Gene

(2011) Ramin Tadayoni et al.   MOLECULAR NEUROBIOLOGY

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Daily Treatment with SMTC1100, a Novel Small Molecule Utrophin Upregulator, Dramatically Reduces the Dystrophic Symptoms in the mdx Mouse

(2011) Jonathon M. Tinsley et al.   PLoS One

Drug screening in a zebrafish model of Duchenne muscular dystrophy

(2011) G. Kawahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization

(2011) M. M. Duszczyk et al.   RNA

DNA Damage, Somatic Aneuploidy, and Malignant Sarcoma Susceptibility in Muscular Dystrophies

(2011) Wolfgang M. Schmidt et al.   PLoS Genetics

Molecular and Clinicopathologic Characterization of Gastrointestinal Stromal Tumors (GISTs) of Small Size

(2010) Sabrina Rossi et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

AAV-directed muscular dystrophy gene therapy

(2010) Ying Tang et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Kitlow Stem Cells Cause Resistance to Kit/Platelet-Derived Growth Factor α Inhibitors in Murine Gastrointestinal Stromal Tumors

(2010) Michael R. Bardsley et al.   GASTROENTEROLOGY

Loss of Kitlowprogenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice

(2010) Ferenc Izbeki et al.   JOURNAL OF PHYSIOLOGY-LONDON

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

(2010) Jordi Barretina et al.   NATURE GENETICS

Muscling in: Uncovering the origins of rhabdomyosarcoma

(2010) Simone Hettmer et al.   NATURE MEDICINE

Mice Lacking Dystrophin or α Sarcoglycan Spontaneously Develop Embryonal Rhabdomyosarcoma with Cancer-Associated p53 Mutations and Alternatively Spliced or Mutant Mdm2 Transcripts

(2009) Karen Fernandez et al.   AMERICAN JOURNAL OF PATHOLOGY

G-protein-coupled-receptor kinases mediate TNFα-induced NF-κB signalling via direct interaction with and phosphorylation of IκBα

(2009) Sonika Patial et al.   BIOCHEMICAL JOURNAL