Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

CXCR4/CXCL12 Mediate Autocrine Cell- Cycle Progression in NF1-Associated Malignant Peripheral Nerve Sheath Tumors

(2013) Wei Mo et al.   CELL

Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems

(2012) Fausto J. Rodriguez et al.   ACTA NEUROPATHOLOGICA

Mutational analysis of PIK3CA,JAK2,BRAF,FOXL2,IDH1,AKT1 and EZH2 oncogenes in sarcomas

(2012) Eun M. Je et al.   APMIS

TAPDANCE: An automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data

(2012) Aaron L Sarver et al.   BMC BIOINFORMATICS

PTEN and NF1 Inactivation in Schwann Cells Produces a Severe Phenotype in the Peripheral Nervous System That Promotes the Development and Malignant Progression of Peripheral Nerve Sheath Tumors

(2012) V. W. Keng et al.   CANCER RESEARCH

Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring

(2012) Anthony E Rizzardi et al.   Diagnostic Pathology

A Transposon-Based Analysis of Gene Mutations Related to Skin Cancer Development

(2012) Rita M. Quintana et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Targeting the PI3K/mTOR Axis, Alone and in Combination with Autophagy Blockade, for the Treatment of Malignant Peripheral Nerve Sheath Tumors

(2012) M. P. Ghadimi et al.   MOLECULAR CANCER THERAPEUTICS

Clonal selection drives genetic divergence of metastatic medulloblastoma

(2012) Xiaochong Wu et al.   NATURE

Malignant Peripheral Nerve Sheath Tumors (MPNST): The Mayo Clinic Experience

(2011) Chee-Chee H. Stucky et al.   ANNALS OF SURGICAL ONCOLOGY

Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment

(2011) J. Yang et al.   CLINICAL CANCER RESEARCH

Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors

(2011) A. Feber et al.   GENOME RESEARCH

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity

(2011) Claudio Mussolino et al.   NUCLEIC ACIDS RESEARCH

Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma

(2011) E E Santo et al.   ONCOGENE

Novel Molecular and Computational Methods Improve the Accuracy of Insertion Site Analysis in Sleeping Beauty-Induced Tumors

(2011) Benjamin T. Brett et al.   PLoS One

Targeted Genome Editing Across Species Using ZFNs and TALENs

(2011) Andrew J. Wood et al.   SCIENCE

A TALE nuclease architecture for efficient genome editing

(2010) Jeffrey C Miller et al.   NATURE BIOTECHNOLOGY

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Transient cold shock enhances zinc-finger nuclease–mediated gene disruption

(2010) Yannick Doyon et al.   NATURE METHODS

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

S100A1 Expression in Ovarian and Endometrial Endometrioid Carcinomas Is a Prognostic Indicator of Relapse-Free Survival

(2009) Melissa S. DeRycke et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Clinical, Pathological, and Molecular Variables Predictive of Malignant Peripheral Nerve Sheath Tumor Outcome

(2009) Changye Zou et al.   ANNALS OF SURGERY

Deletion of the WWOX gene and frequent loss of its protein expression in human osteosarcoma

(2009) Jilong Yang et al.   CANCER LETTERS

A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice

(2009) A. J. Dupuy et al.   CANCER RESEARCH

Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours

(2009) Subbaya Subramanian et al.   JOURNAL OF PATHOLOGY

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma

(2009) Vincent W Keng et al.   NATURE BIOTECHNOLOGY

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Integrated study of copy number states and genotype calls using high-density SNP arrays

(2009) Wei Sun et al.   NUCLEIC ACIDS RESEARCH

PTEN dosage is essential for neurofibroma development and malignant transformation

(2009) C. Gregorian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

(2009) T. K. Starr et al.   SCIENCE

Multinucleated floret-like giant cells in sporadic and NF1-associated neurofibromas: a clinicopathologic study of 94 cases

(2009) Gaetano Magro et al.   VIRCHOWS ARCHIV

Plexiform and Dermal Neurofibromas and Pigmentation Are Caused by Nf1 Loss in Desert Hedgehog-Expressing Cells

(2008) Jianqiang Wu et al.   CANCER CELL

High-Resolution DNA Copy Number Profiling of Malignant Peripheral Nerve Sheath Tumors Using Targeted Microarray-Based Comparative Genomic Hybridization

(2008) K. K. Mantripragada et al.   CLINICAL CANCER RESEARCH