期刊
NATURE GENETICS
卷 40, 期 10, 页码 1149-1150出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ng1008-1149
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Kras, Hras or Nras mutations occur at varying frequencies across different tumors in humans for unknown reasons. a new study shows that, in mice, locus-specific regulatory elements determine whether mutations in Hras or Kras will predominate in lung and skin tumors.
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