Molecular tweezers modulate 14-3-3 protein–protein interactions

An Optimised Small-Molecule Stabiliser of the 14-3-3-PMA2 Protein-Protein Interaction

(2012) Anja Richter et al.   CHEMISTRY-A EUROPEAN JOURNAL

Protein camouflage in cytochrome c–calixarene complexes

(2012) Róise E. McGovern et al.   Nature Chemistry

Molecular Recognition of Insulin by a Synthetic Receptor

(2011) Jordan M. Chinai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

(2011) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a 14-3-3σ–YAP phosphopeptide complex at 1.15 Å resolution

(2010) Benjamin Schumacher et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Microarray-Assisted High-Throughput Identification of a Cell-Permeable Small-Molecule Binder of 14-3-3 Proteins

(2010) Hao Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification and Structure of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions

(2010) Rolf Rose et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of the first non-peptidic small molecule inhibitor of the c-Abl/14-3-3 protein–protein interactions able to drive sensitive and Imatinib-resistant leukemia cells to apoptosis

(2010) Valentina Corradi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer

(2010) Benjamin Schumacher et al.   FEBS LETTERS

Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling

(2010) M. Molzan et al.   MOLECULAR AND CELLULAR BIOLOGY

Effect of molecular clips and tweezers on enzymatic reactions by binding coenzymes and basic amino acids

(2010) Frank-Gerrit Klärner et al.   PURE AND APPLIED CHEMISTRY

Protein Dimerization Induced by Supramolecular Interactions with Cucurbit[8]uril

(2009) Hoang D. Nguyen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms

(2009) Sridharan Rajagopalan et al.   NUCLEIC ACIDS RESEARCH

Calix[4]arene-based conical-shaped ligands for voltage-dependent potassium channels

(2009) V. Martos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding to protein surfaces by supramolecular multivalent scaffolds

(2008) Vera Martos et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Molecular Clip and Tweezer Introduce New Mechanisms of Enzyme Inhibition

(2008) Peter Talbiersky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A structural link between inactivation and block of a K+ channel

(2008) Christian Ader et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligand

(2008) S. Gordo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

(2008) Deborah K. Morrison   TRENDS IN CELL BIOLOGY