Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor

Macrocyclic β-Sheet Peptides That Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide

(2011) Jing Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

2DIR Spectroscopy of Human Amylin Fibrils Reflects Stable β-Sheet Structure

(2011) Lu Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intermolecular Structure Determination of Amyloid Fibrils with Magic-Angle Spinning and Dynamic Nuclear Polarization NMR

(2011) Marvin J. Bayro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation

(2011) Stuart A. Sievers et al.   NATURE

Tidal surge in the M2 proton channel, sensed by 2D IR spectroscopy

(2011) A. Ghosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Residue-Specific Vibrational Echoes Yield 3D Structures of a Transmembrane Helix Dimer

(2011) A. Remorino et al.   SCIENCE

Suppression of IAPP fibrillation at anionic lipid membranes via IAPP-derived amyloid inhibitors and insulin

(2010) Daniel Sellin et al.   BIOPHYSICAL CHEMISTRY

Solution Structures of Rat Amylin Peptide: Simulation, Theory, and Experiment

(2010) Allam S. Reddy et al.   BIOPHYSICAL JOURNAL

Melting of a β-Hairpin Peptide Using Isotope-Edited 2D IR Spectroscopy and Simulations

(2010) Adam W. Smith et al.   JOURNAL OF PHYSICAL CHEMISTRY B

2D IR Line Shapes Probe Ovispirin Peptide Conformation and Depth in Lipid Bilayers

(2010) Ann Marie Woys et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combination of Kinetically Selected Inhibitorsin TransLeads to Highly Effective Inhibition of Amyloid Formation

(2010) Fanling Meng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Residue-specific structural kinetics of proteins through the union of isotope labeling, mid-IR pulse shaping, and coherent 2D IR spectroscopy

(2010) Chris T. Middleton et al.   METHODS

Efficient Microwave-Assisted Synthesis of Human Islet Amyloid Polypeptide Designed to Facilitate the Specific Incorporation of Labeled Amino Acids

(2010) Peter Marek et al.   ORGANIC LETTERS

The Ability of Rodent Islet Amyloid Polypeptide To Inhibit Amyloid Formation by Human Islet Amyloid Polypeptide Has Important Implications for the Mechanism of Amyloid Formation and the Design of Inhibitors

(2009) Ping Cao et al.   BIOCHEMISTRY

Two-dimensional Infrared Spectroscopy Provides Evidence of an Intermediate in the Membrane-catalyzed Assembly of Diabetic Amyloid

(2009) Yun L. Ling et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Strategies for Extracting Structural Information from 2D IR Spectroscopy of Amyloid: Application to Islet Amyloid Polypeptide

(2009) David B. Strasfeld et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Couplings between Peptide Linkages across a 310-Helical Hydrogen Bond Revealed by Two-Dimensional Infrared Spectroscopy

(2009) Hiroaki Maekawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

2D IR provides evidence for mobile water molecules in  -amyloid fibrils

(2009) Y. S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution

(2009) S.-H. Shim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and mechanistic basis behind the inhibitory interaction of PcTS on α-synuclein amyloid fibril formation

(2009) Gonzalo R. Lamberto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gating Mechanism of the Influenza A M2 Channel Revealed by 1D and 2D IR Spectroscopies

(2009) Joshua Manor et al.   STRUCTURE

Peptide and Protein Mimetics Inhibiting Amyloid β-Peptide Aggregation

(2008) Tsuyoshi Takahashi et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Binding of Thioflavin T and Its Neutral Analog BTA-1 to Protofibrils of the Alzheimer’s Disease Aβ16–22 Peptide Probed by Molecular Dynamics Simulations

(2008) Chun Wu et al.   JOURNAL OF MOLECULAR BIOLOGY

Coherent Two Dimensional Infrared Spectroscopy of a Cyclic Decapeptide Antamanide. A Simulation Study of the Amide-I and A Bands

(2008) Cyril Falvo et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Escaping amyloid fate

(2008) Blake E Roberts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

How to turn your pump–probe instrument into a multidimensional spectrometer: 2D IR and Vis spectroscopiesvia pulse shaping

(2008) Sang-Hee Shim et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Two-dimensional infrared spectra of isotopically diluted amyloid fibrils from A 40

(2008) Y. S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

(2008) Jed J.W. Wiltzius et al.   PROTEIN SCIENCE