标题
Engineering synthetic recursive pathways to generate non-natural small molecules
作者
关键词
-
出版物
Nature Chemical Biology
Volume 8, Issue 6, Pages 518-526
出版商
Springer Nature
发表日期
2012-05-18
DOI
10.1038/nchembio.959
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production
- (2012) Yongjin J. Zhou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Engineering of Bacterial Methyl Ketone Synthesis for Biofuels
- (2011) Ee-Been Goh et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Engineering of an “Unnatural” Natural Product by Swapping Polyketide Synthase Domains inAspergillus nidulans
- (2011) Ting Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Optimization of a heterologous pathway for the production of flavonoids from glucose
- (2011) Christine Nicole S. Santos et al. METABOLIC ENGINEERING
- Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals
- (2011) Clementina Dellomonaco et al. NATURE
- From Amino Acid to Glucosinolate Biosynthesis: Protein Sequence Changes in the Evolution of Methylthioalkylmalate Synthase inArabidopsis
- (2011) Jan-Willem de Kraker et al. PLANT CELL
- Phenotype Sequencing: Identifying the Genes That Cause a Phenotype Directly from Pooled Sequencing of Independent Mutants
- (2011) Marc A. Harper et al. PLoS One
- Modularity of a carbon-fixing protein organelle
- (2011) W. Bonacci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic Engineering for the Production of Natural Products
- (2011) Lauren B. Pickens et al. Annual Review of Chemical and Biomolecular Engineering
- A process for microbial hydrocarbon synthesis: Overproduction of fatty acids inEscherichia coliand catalytic conversion to alkanes
- (2010) Rebecca M. Lennen et al. BIOTECHNOLOGY AND BIOENGINEERING
- Sesquiterpene Synthases Cop4 and Cop6 from Coprinus cinereus: Catalytic Promiscuity and Cyclization of Farnesyl Pyrophosphate Geometric Isomers
- (2010) Fernando Lopez-Gallego et al. CHEMBIOCHEM
- Tailoring plant lipid composition: designer oilseeds come of age
- (2010) Johnathan A Napier et al. CURRENT OPINION IN PLANT BIOLOGY
- Mechanism and Engineering of Polyketide Chain Initiation in Fredericamycin Biosynthesis
- (2010) Abhirup Das et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Exploiting Enzymatic Promiscuity to Engineer a Focused Library of Highly Selective Antifungal and Antiproliferative Aureothin Analogues
- (2010) Martina Werneburg et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biosynthesis of the Allylmalonyl-CoA Extender Unit for the FK506 Polyketide Synthase Proceeds through a Dedicated Polyketide Synthase and Facilitates the Mutasynthesis of Analogues
- (2010) SangJoon Mo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis of Empty Bacterial Microcompartments, Directed Organelle Protein Incorporation, and Evidence of Filament-Associated Organelle Movement
- (2010) Joshua B. Parsons et al. MOLECULAR CELL
- Microbial production of fatty-acid-derived fuels and chemicals from plant biomass
- (2010) Eric J. Steen et al. NATURE
- Organocatalytic cascade reactions as a new tool in total synthesis
- (2010) Christoph Grondal et al. Nature Chemistry
- New insights into the formation of fungal aromatic polyketides
- (2010) Jason M. Crawford et al. NATURE REVIEWS MICROBIOLOGY
- Short N-terminal sequences package proteins into bacterial microcompartments
- (2010) C. Fan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evaluation and ranking of enzyme designs
- (2010) Gert Kiss et al. PROTEIN SCIENCE
- Structure and Mechanisms of a Protein-Based Organelle in Escherichia coli
- (2010) S. Tanaka et al. SCIENCE
- Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli
- (2010) P. K. Ajikumar et al. SCIENCE
- Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
- (2010) J. B. Siegel et al. SCIENCE
- Biosynthesis of glucosinolates – gene discovery and beyond
- (2010) Ida E. Sønderby et al. TRENDS IN PLANT SCIENCE
- Advances in Quantum and Molecular Mechanical (QM/MM) Simulations for Organic and Enzymatic Reactions
- (2009) Orlando Acevedo et al. ACCOUNTS OF CHEMICAL RESEARCH
- A Thioesterase from an Iterative Fungal Polyketide Synthase Shows Macrocyclization and Cross Coupling Activity and May Play a Role in Controlling Iterative Cycling through Product Offloading
- (2009) Meng Wang et al. BIOCHEMISTRY
- Mapping the Limits of Substrate Specificity of the Adenylation Domain of TycA
- (2009) Benoit R. M. Villiers et al. CHEMBIOCHEM
- Stereospecific Living Radical Polymerization: Dual Control of Chain Length and Tacticity for Precision Polymer Synthesis
- (2009) Kotaro Satoh et al. CHEMICAL REVIEWS
- Directed enzyme evolution: climbing fitness peaks one amino acid at a time
- (2009) Cara A Tracewell et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Nucleobase-Templated Polymerization: Copying the Chain Length and Polydispersity of Living Polymers into Conjugated Polymers
- (2009) Pik Kwan Lo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering
- (2009) Wenjuan Zha et al. METABOLIC ENGINEERING
- Synthetic protein scaffolds provide modular control over metabolic flux
- (2009) John E Dueber et al. NATURE BIOTECHNOLOGY
- Covalent Linkage Mediates Communication between ACP and TE Domains in Modular Polyketide Synthases
- (2008) Lucky Tran et al. CHEMBIOCHEM
- Unearthing the roots of the terpenome
- (2008) David W Christianson CURRENT OPINION IN CHEMICAL BIOLOGY
- Methanogen Homoaconitase Catalyzes Both Hydrolyase Reactions in Coenzyme B Biosynthesis
- (2008) Randy M. Drevland et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A novel method for enzyme design
- (2008) Xiaolei Zhu et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Metabolic engineering of Escherichia coli for 1-butanol and 1-propanol production via the keto-acid pathways
- (2008) C.R. Shen et al. METABOLIC ENGINEERING
- Overproduction of free fatty acids in E. coli: Implications for biodiesel production
- (2008) Xuefeng Lu et al. METABOLIC ENGINEERING
- Nonribosomal Peptide Synthetases Involved in the Production of Medically Relevant Natural Products
- (2008) Elizabeth A. Felnagle et al. MOLECULAR PHARMACEUTICS
- Kemp elimination catalysts by computational enzyme design
- (2008) Daniela Röthlisberger et al. NATURE
- Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
- (2008) Shota Atsumi et al. NATURE
- Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases
- (2008) Paul E O'Maille et al. Nature Chemical Biology
- MODBASE, a database of annotated comparative protein structure models and associated resources
- (2008) U. Pieper et al. NUCLEIC ACIDS RESEARCH
- Methylthioalkylmalate synthases: genetics, ecology and evolution
- (2008) Markus Benderoth et al. PHYTOCHEMISTRY REVIEWS
- Transcriptomic and Reverse Genetic Analysesof Branched-Chain Fatty Acid and Acyl Sugar Production in Solanum pennellii and Nicotiana benthamiana
- (2008) S. P. Slocombe et al. PLANT PHYSIOLOGY
- Expanding metabolism for biosynthesis of nonnatural alcohols
- (2008) K. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- De Novo Computational Design of Retro-Aldol Enzymes
- (2008) L. Jiang et al. SCIENCE
- Redirecting the Cyclization Steps of Fungal Polyketide Synthase
- (2007) Suzanne M. Ma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More