Unusual carbon fixation gives rise to diverse polyketide extender units

A Branched Extender Unit Shared between Two Orthogonal Polyketide Pathways in an Endophyte

(2011) Zhongli Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of 2-Octenoyl-CoA Carboxylase/Reductase UtilizingpteBfromStreptomyce avermitilis

(2011) Hye-Gyeong YOO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Mining the Cinnabaramide Biosynthetic Pathway to Generate Novel Proteasome Inhibitors

(2011) Shwan Rachid et al.   CHEMBIOCHEM

Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690

(2011) Maren Kopp et al.   Molecular BioSystems

Biosynthesis of Thuggacins in Myxobacteria: Comparative Cluster Analysis Reveals Basis for Natural Product Structural Diversity

(2010) Kathrin Buntin et al.   CHEMISTRY & BIOLOGY

Origin of the Allyl Group in FK506 Biosynthesis

(2010) Dušan Goranovič et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regio- and Stereospecificity of Filipin Hydroxylation Sites Revealed by Crystal Structures of Cytochrome P450 105P1 and 105D6 fromStreptomyces avermitilis

(2010) Lian-Hua Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis of the Allylmalonyl-CoA Extender Unit for the FK506 Polyketide Synthase Proceeds through a Dedicated Polyketide Synthase and Facilitates the Mutasynthesis of Analogues

(2010) SangJoon Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor

(2010) Xudong Qu et al.   Molecular BioSystems

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three-dimensional Structure and Enzymatic Function of Proapoptotic Human p53-inducible Quinone Oxidoreductase PIG3

(2009) Sergio Porté et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine

(2009) A. S. Eustaquio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase

(2009) T. J. Erb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA