期刊
NATURE CHEMICAL BIOLOGY
卷 6, 期 3, 页码 205-207出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/NCHEMBIO.311
关键词
-
资金
- US National Institutes of Health [P01-ES013125]
- Vanderbilt Institute of Chemical Biology Pilot Program
- National Institutes of Health Grant Lipid Maps [U54 GM69338]
Alkyne-modified phospholipids can be unambiguously identified and differentiated from native species in complex mixtures by formation of dicobalthexacarbonyl complexes. This reaction is specific for alkynes and is unaffected by other glycerophospholipid-related moieties. Enrichment of cells with alkyne-derivatized fatty acids or glycerophospholipids followed by solid-phase sequestration and release is a promising new method for unequivocally monitoring individual glycerophospholipids following incorporation into cells. This technique also facilitates lipidomic analysis of substrates and products.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据