Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3

Molecular Mechanism of Autophagic Membrane-Scaffold Assembly and Disassembly

(2014) Anna Kaufmann et al.   CELL

Conical Lipids in Flat Bilayers Induce Packing Defects Similar to that Induced by Positive Curvature

(2013) Lydie Vamparys et al.   BIOPHYSICAL JOURNAL

Amphipathic Lipid Packing Sensor Motifs: Probing Bilayer Defects with Hydrophobic Residues

(2013) Stefano Vanni et al.   BIOPHYSICAL JOURNAL

Atg12–Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site

(2013) Machiko Sakoh-Nakatogawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis

(2012) Hitoshi Nakatogawa et al.   Autophagy

Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

(2012) Michael J. Ragusa et al.   CELL

Structure of the Atg12–Atg5 conjugate reveals a platform for stimulating Atg8–PE conjugation

(2012) Nobuo N Noda et al.   EMBO REPORTS

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

SNARE Proteins Are Required for Macroautophagy

(2011) Usha Nair et al.   CELL

α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding

(2011) Iwona M. Pranke et al.   JOURNAL OF CELL BIOLOGY

Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes

(2011) Tassula Proikas-Cezanne et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)

(2011) W. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atg8: an autophagy-related ubiquitin-like protein family

(2011) Tomer Shpilka et al.   GENOME BIOLOGY

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation

(2010) Mitsuko Hayashi-Nishino et al.   Autophagy

ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death

(2010) Lilliana Radoshevich et al.   CELL

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

(2010) James E. Brownell et al.   MOLECULAR CELL

The amino-terminal region of Atg3 is essential for association with phosphatidylethanolamine in Atg8 lipidation

(2009) Takao Hanada et al.   FEBS LETTERS

Amphipathic helices and membrane curvature

(2009) Guillaume Drin et al.   FEBS LETTERS

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

(2009) Mitsuko Hayashi-Nishino et al.   NATURE CELL BIOLOGY

How curved membranes recruit amphipathic helices and protein anchoring motifs

(2009) Nikos S Hatzakis et al.   Nature Chemical Biology

Measurement of the membrane curvature preference of phospholipids reveals only weak coupling between lipid shape and leaflet curvature

(2009) Marzuk M. Kamal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

Physiological pH and Acidic Phospholipids Contribute to Substrate Specificity in Lipidation of Atg8

(2008) Kyoko Oh-oka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice

(2008) Yu-shin Sou et al.   MOLECULAR BIOLOGY OF THE CELL

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL