IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

Partners in death: a role for p73 and NF-kB in promoting apoptosis

(2016) Karen H. Vousden   Aging-US

Inflammatory cause of metabolic syndrome via brain stress and NF-κB

(2016) Dongsheng Cai et al.   Aging-US

Hypothalamic inflammation: a double-edged sword to nutritional diseases

(2012) Dongsheng Cai et al.   Annals of the New York Academy of Sciences

Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

(2012) Daniel A Lee et al.   NATURE NEUROSCIENCE

Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice

(2011) David E.G. McNay et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB

(2011) Sudarshana Purkayastha et al.   NATURE MEDICINE

Neuropeptide Exocytosis Involving Synaptotagmin-4 and Oxytocin in Hypothalamic Programming of Body Weight and Energy Balance

(2011) Guo Zhang et al.   NEURON

Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress

(2011) S. Purkayastha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De Novo Neurogenesis in Adult Hypothalamus as a Compensatory Mechanism to Regulate Energy Balance

(2010) A. A. Pierce et al.   JOURNAL OF NEUROSCIENCE

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

Nuclear factor- B is a critical mediator of stress-impaired neurogenesis and depressive behavior

(2010) J. W. Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Notch Signaling in Human Embryonic Stem Cell-Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and In Vivo

(2010) Lodovica Borghese et al.   STEM CELLS

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke

(2009) Marie Carlén et al.   NATURE NEUROSCIENCE

Adult neurogenesis and the olfactory system

(2009) Mary C. Whitman et al.   PROGRESS IN NEUROBIOLOGY

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Impaired Adult Neurogenesis Associated with Short-Term Memory Defects in NF- B p50-Deficient Mice

(2008) S. Denis-Donini et al.   JOURNAL OF NEUROSCIENCE

Microglia—A Wrench in the Running Wheel?

(2008) Saul Villeda et al.   NEURON

Attenuation of Notch signaling promotes the differentiation of neural progenitors into neurons in the hippocampal CA1 region after ischemic injury

(2008) S. Oya et al.   NEUROSCIENCE

IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress

(2008) J. W. Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA