PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
出版年份 2018 全文链接
标题
PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
作者
关键词
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出版物
NATURE
Volume 559, Issue 7714, Pages 423-427
出版商
Springer Nature
发表日期
2018-07-10
DOI
10.1038/s41586-018-0325-6
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor
- (2018) Tao Che et al. CELL
- Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure
- (2017) Xiangyu Liu et al. NATURE
- Trends in GPCR drug discovery: new agents, targets and indications
- (2017) Alexander S. Hauser et al. NATURE REVIEWS DRUG DISCOVERY
- Ligand binding to a G protein–coupled receptor captured in a mass spectrometer
- (2017) Hsin-Yung Yen et al. Science Advances
- Mini-G proteins: Novel tools for studying GPCRs in their active conformation
- (2017) Rony Nehmé et al. PLoS One
- Lipid interaction sites on channels, transporters and receptors: Recent insights from molecular dynamics simulations
- (2016) George Hedger et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association
- (2016) Jan Domański et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Free Energy Landscape of Lipid Interactions with Regulatory Binding Sites on the Transmembrane Domain of the EGF Receptor
- (2016) George Hedger et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Structure of the adenosine A2A receptor bound to an engineered G protein
- (2016) Byron Carpenter et al. NATURE
- Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists
- (2016) Yi Zheng et al. NATURE
- Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
- (2016) A. J. Venkatakrishnan et al. NATURE
- High-resolution mass spectrometry of small molecules bound to membrane proteins
- (2016) Joseph Gault et al. NATURE METHODS
- Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles
- (2015) Michael T. Marty et al. ANALYTICAL CHEMISTRY
- Allosteric regulation of G protein–coupled receptor activity by phospholipids
- (2015) Rosie Dawaliby et al. Nature Chemical Biology
- A subset of annular lipids is linked to the flippase activity of an ABC transporter
- (2015) Chérine Bechara et al. Nature Chemistry
- Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution
- (2015) Matthias Hillenbrand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A cleavable ligand column for the rapid isolation of large quantities of homogeneous and functional neurotensin receptor 1 variants from E. coli
- (2015) Pascal Egloff et al. PROTEIN EXPRESSION AND PURIFICATION
- The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids
- (2015) George Hedger et al. Scientific Reports
- Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies
- (2014) Daniel J. Scott et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Structural Features of β2 Adrenergic Receptor: Crystal Structures and Beyond
- (2014) Injin Bang et al. MOLECULES AND CELLS
- The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor
- (2014) Jennifer L. Miller-Gallacher et al. PLoS One
- Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution inEscherichia coli
- (2014) Pascal Egloff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers
- (2014) Heidi Koldsø et al. PLoS Computational Biology
- Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody
- (2013) Aaron M. Ring et al. NATURE
- Mass spectrometry of intact membrane protein complexes
- (2013) Arthur Laganowsky et al. Nature Protocols
- Improved Parameters for the Martini Coarse-Grained Protein Force Field
- (2012) Djurre H. de Jong et al. Journal of Chemical Theory and Computation
- Biophysical characterization of membrane proteins in nanodiscs
- (2012) Sayaka Inagaki et al. METHODS
- Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations
- (2012) K. M. Schlinkmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cholesterol increases kinetic, energetic, and mechanical stability of the human 2-adrenergic receptor
- (2012) M. Zocher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2
- (2011) Scott B. Hansen et al. NATURE
- The structural basis for agonist and partial agonist action on a β1-adrenergic receptor
- (2011) Tony Warne et al. NATURE
- Structure of a nanobody-stabilized active state of the β2 adrenoceptor
- (2011) Søren G. F. Rasmussen et al. NATURE
- Lipidomics Profiling by High-Resolution LC−MS and High-Energy Collisional Dissociation Fragmentation: Focus on Characterization of Mitochondrial Cardiolipins and Monolysocardiolipins
- (2010) Susan S. Bird et al. ANALYTICAL CHEMISTRY
- g_wham—A Free Weighted Histogram Analysis Implementation Including Robust Error and Autocorrelation Estimates
- (2010) Jochen S. Hub et al. Journal of Chemical Theory and Computation
- ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments
- (2009) Charles Simon Bond et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Combining an Elastic Network With a Coarse-Grained Molecular Force Field: Structure, Dynamics, and Intermolecular Recognition
- (2009) Xavier Periole et al. Journal of Chemical Theory and Computation
- Development and crystallization of a minimal thermostabilised G protein-coupled receptor
- (2009) Tony Warne et al. PROTEIN EXPRESSION AND PURIFICATION
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- Structure of a β1-adrenergic G-protein-coupled receptor
- (2008) Tony Warne et al. NATURE
- Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure
- (2007) Christopher B. Roth et al. JOURNAL OF MOLECULAR BIOLOGY
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