Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis

(2018) Max L. Senders et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Oxidation-specific epitopes restrain bone formation

(2018) Elena Ambrogini et al.   Nature Communications

By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation

(2017) Ivan Zanoni et al.   IMMUNITY

A Test in Context: Lipoprotein(a)

(2017) Sotirios Tsimikas   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

(2017) Beatrice Oehler et al.   Scientific Reports

Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice

(2016) Boyi Liu et al.   PLoS One

The Nuclear Receptor Nr4a1 Controls CD8 T Cell Development Through Transcriptional Suppression of Runx3

(2015) Heba N. Nowyhed et al.   Scientific Reports

Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse

(2014) Randy T. Cowling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

ABCG1 Is Required for Pulmonary B-1 B Cell and Natural Antibody Homeostasis

(2014) Angel Baldan et al.   JOURNAL OF IMMUNOLOGY

Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine

(2014) Ayelet Gonen et al.   JOURNAL OF LIPID RESEARCH

Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies

(2014) Dimitrios Tsiantoulas et al.   JOURNAL OF LIPID RESEARCH

Imaging of Oxidation-Specific Epitopes with Targeted Nanoparticles to Detect High-Risk Atherosclerotic Lesions: Progress and Future Directions

(2014) Karen Briley-Saebo et al.   Journal of Cardiovascular Translational Research

Molecular and Cellular Aspects of Calcific Aortic Valve Disease

(2013) Dwight A. Towler   CIRCULATION RESEARCH

Development and application of a nonradioactive binding assay of oxidized low-density lipoprotein to macrophage scavenger receptors

(2013) Erica N. Montano et al.   JOURNAL OF LIPID RESEARCH

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

Role of Phospholipid Oxidation Products in Atherosclerosis

(2012) Sangderk Lee et al.   CIRCULATION RESEARCH

Design and Synthesis of a Stable Oxidized Phospholipid Mimic with Specific Binding Recognition for Macrophage Scavenger Receptors

(2012) William W. Turner et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

(2011) Yury I. Miller et al.   CIRCULATION RESEARCH

Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2

(2011) Alexandra Kadl et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human Oxidation-Specific Antibodies Reduce Foam Cell Formation and Atherosclerosis Progression

(2011) Sotirios Tsimikas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress

(2010) Tracie A. Seimon et al.   Cell Metabolism

Lipoprotein Accumulation in Macrophages via Toll-Like Receptor-4–Dependent Fluid Phase Uptake

(2009) Soo-Ho Choi et al.   CIRCULATION RESEARCH

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

(2009) Meng-Yun Chou et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL