Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

Predisposition gene identification in common cancers by exome sequencing: insights from familial breast cancer

(2012) Katie Snape et al.   BREAST CANCER RESEARCH AND TREATMENT

Evaluation of Association Methods for Analysing Modifiers of Disease Risk in Carriers of High-Risk Mutations

(2012) Daniel R. Barnes et al.   GENETIC EPIDEMIOLOGY

Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection

(2012) Lucia Hernandez et al.   JOURNAL OF PATHOLOGY

Detectable clonal mosaicism and its relationship to aging and cancer

(2012) Kevin B Jacobs et al.   NATURE GENETICS

Detectable clonal mosaicism from birth to old age and its relationship to cancer

(2012) Cathy C Laurie et al.   NATURE GENETICS

Germline RAD51C mutations confer susceptibility to ovarian cancer

(2012) Chey Loveday et al.   NATURE GENETICS

Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)

(2011) Ryo Hayashi et al.   BIOCHEMISTRY

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Germline mutations in RAD51D confer susceptibility to ovarian cancer

(2011) Chey Loveday et al.   NATURE GENETICS

The inherited genetics of ovarian and endometrial cancer

(2010) Simon A Gayther et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Stampy: A statistical algorithm for sensitive and fast mapping of Illumina sequence reads

(2010) G. Lunter et al.   GENOME RESEARCH

Genome-wide association study identifies five new breast cancer susceptibility loci

(2010) Clare Turnbull et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers

(2009) R. Natrajan et al.   CLINICAL CANCER RESEARCH

PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas

(2009) D. S.P. Tan et al.   CLINICAL CANCER RESEARCH

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

(2009) Andreas Gnirke et al.   NATURE BIOTECHNOLOGY

Genetic Predisposition to Breast Cancer: Past, Present, and Future

(2008) Clare Turnbull et al.   Annual Review of Genomics and Human Genetics

The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways

(2008) Xiongbin Lu et al.   CANCER AND METASTASIS REVIEWS

PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression

(2008) Y. Chuman et al.   JOURNAL OF BIOCHEMISTRY

Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay

(2008) A. L. Silva et al.   RNA